太田痣合并蓝痣一例

doi:10.24920/004092

Chinese Medical Sciences Journal ›› 2023, Vol. 38 ›› Issue (1): 70-72.doi: 10.24920/004092

• 病例报告 • 上一篇

太田痣合并蓝痣一例

刘杏¹,郑慧颖¹,方富民¹,杨荷丹¹,丁徽¹,杨寅¹,葛一平^1,^*(),林彤^2,^*()

¹激光科，中国医学科学院　北京协和医学院皮肤病医院（研究所），南京 210042，中国
²江苏省皮肤病与性病分子生物学重点实验室，中国医学科学院　北京协和医学院皮肤病医院（研究所），南京 210042，中国

收稿日期:2022-04-02 接受日期:2022-07-28 出版日期:2023-03-31 发布日期:2023-02-02
通讯作者: 葛一平,林彤 E-mail:gypfeng@hotmail.com;ddlin@hotmail.com

Blue Nevus Hidden within the Nevus of Ota

Xing Liu¹,Hui-Ying Zheng¹,Fu-Min Fang¹,He-Dan Yang¹,Hui Ding¹,Yin Yang¹,Yi-Ping Ge^1,^*(),Tong Lin^2,^*()

¹Department of Cosmetic Laser Surgery, Institute of Dermatology, Chinese Academy of Medical Sciences & Peking Union Medical College, Nanjing 210042, China
²Jiangsu Key Laboratory of Molecular Biology for Skin Diseases and STIs, Institute of Dermatology, Chinese Academy of Medical Sciences & Peking Union Medical College, Nanjing 210042, China

Received:2022-04-02 Accepted:2022-07-28 Published:2023-03-31 Online:2023-02-02
Contact: Yi-Ping Ge,Tong Lin E-mail:gypfeng@hotmail.com;ddlin@hotmail.com

摘要/Abstract

摘要：

太田痣是一种良性的、色素增多性皮肤病，皮损好发于面部，一般表现为单侧褐色至蓝色斑片。虽然该病通常情况下是良性的，但可能合并其他色素增多性疾病甚至恶变为黑素瘤。我们报道一例3岁男孩在左脸出现蓝色斑片和分散分布的蓝色斑点，经过几次激光治疗后，眼眶周围的蓝色斑块颜色逐渐加深，组织病理检查发现真皮可见多数双极树突状细胞，胞浆内含有色素颗粒，组化结果为S100(+)，SOX-10(+)，Melan-A(+)，P16(+)，HMB-45(+)，Ki-67<5%。最后，诊断为太田痣合并蓝痣。因此，对于激光治疗效果不佳的太田痣，应怀疑可能同时存在其他疾病，需要进一步随访。

关键词: 太田痣, 蓝痣, 激光治疗

Abstract:

A 3-year-old boy presented with bluish patch and scattered blue spots on the left side of his face. After several sessions of laser treatment, the azury patch in the periorbital area became even darker. Histopathology showed many bipolar, pigment-laden dendritic cells scattered in the papillary and upper reticular dermis. Immunohistochemically, these cells were positive for S100, SOX-10, melan-A, P16, and HMB-45. The positive rate of Ki-67 was less than 5%. Finally, the lesion was diagnosed with nevus of Ota concurrent with common blue nevus. Therefore, for cases of the nevus of Ota with poor response to laser treatment, the possible coexisting diseases should be suspected.

Key words: nevus of Ota, blue nevus, laser therapy

Xing Liu, Hui-Ying Zheng, Fu-Min Fang, He-Dan Yang, Hui Ding, Yin Yang, Yi-Ping Ge, Tong Lin. Blue Nevus Hidden within the Nevus of Ota[J].Chinese Medical Sciences Journal, 2023, 38(1): 70-72.

图/表 2

参考文献 5

[1]	Ge Y, Yang Y, Guo L, et al. Comparison of a picosecond alexandrite laser versus a Q-switched alexandrite laser for the treatment of nevus of Ota: A randomized, split-lesion, controlled trial. J Am Acad Dermatol 2020; 83(2):397-403. doi: 10.1016/j.jaad.2019.03.016. doi: S0190-9622(19)30430-X pmid: 30885760
[2]	Gerami P, Pouryazdanparast P, Vemula S, et al. Molecular analysis of a case of nevus of Ota showing progressive evolution to melanoma with intermediate stages resembling cellular blue nevus. Am J Dermatopathol 2010; 32(3):301-5. doi:10.1097/DAD.0b013e3181b96db7. doi: 10.1097/DAD.0b013e3181b96db7 pmid: 20110797
[3]	Zhao W, Yang X, Wu D. Histopathology and surgical effect of 120 cases of blue nevus. J Dermatol Venereol 2017, 39(2):124-126. doi:10.3969/j.issn.1002-1310.2017.02.021. doi: 10.3969/j.issn.1002-1310.2017.02.021
[4]	Buntinx-Krieg T, Ouyang J, Cartwright M. An orbital malignant melanoma arising in cellular blue nevus in a patient with nevus of Ota. Cureus 2016; 8(7): e698. doi:10.7759/cureus.698. doi: 10.7759/cureus.698
[5]	Hartmann LC, Oliver GF, Winkelmann RK, et al. Blue nevus and nevus of Ota associated with dural melanoma. Cancer 1989; 64(1):182-6. doi: 10.1002/1097-0142(19890701)64:1<182::aid-cncr2820640131>3.0.co;2-p. doi: 10.1002/1097-0142(19890701)64:1<182::aid-cncr2820640131>3.0.co;2-p pmid: 2731113

优先出版

当期目次

过刊浏览

虚拟专题

作者中心

评阅者中心

太田痣合并蓝痣一例

Blue Nevus Hidden within the Nevus of Ota

RichHTML

PDF (PC)

可视化

摘要/Abstract

引用本文

使用本文

图/表 2

参考文献 5

相关文章 0

Metrics

推荐阅读 10