女性生殖系统肾外肾母细胞瘤报道一例及文献回顾

doi:10.24920/J1001-9294.2017.040

摘要/Abstract

摘要：

肾外肾母细胞瘤很罕见。文献中共报道过25例来源于女性生殖系统的肾母细胞瘤。本文报道一例60岁女性以子宫异常出血20天为主诉,超声检查发现宫腔内息肉样肿物,手术病理证实肾外肾母细胞瘤。本文进一步讨论了女性生殖系统肾母细胞瘤的特点,组织学起源,鉴别诊断,治疗及预后,以期促进该罕见肿瘤的正确诊断和治疗。

关键词: 肾外肾母细胞瘤, 子宫, 畸胎瘤样肾母细胞瘤

Abstract:

Extrarenal Wilms’ Tumors (ERWTs) are rare. There have been only 25 cases of ERWT arising from the female genital system reported in the literature. In this paper, we report a 60-year-old woman with a complaint of vaginal bleeding and a polypoid mass in the uterine cavity by sonography that was demonstrated as ERWT by pathology after resection. The pathological characteristics, histological origination, diagnosis, therapy and prognosis of ERWT in female reproductive system are discussed in this paper in the purpose of improving the diagnosis and therapy of this rare tumor.

Key words: extrarenal Wilms’, tumors, uterus, teratoid Wilms’, tumor

Cao Minmin, Huang Cuiping, Wang Yafen, Ma Demei. Extrarenal Wilms’ Tumor of the Female Genital System: A Case Report and Literature Review^△[J].Chinese Medical Sciences Journal, 2017, 32(4): 274-278.

图/表 2

参考文献 31

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Author publish year	Age (y/d)	Presenting symptoms	Tumor charac-teristics	Treatments	Chemotherapeutic regimens	Follow-up	Recurrence
Sahin et al²⁵ 1988	56	Bilateral calf pain, pelvic mass	12cm×11cm×7cm, solid ovoid mass	TAH, BSO, XRT, chemotherapy	Vincristine, dactinomycin, and cyclophosphamide	9 years	NED
Pereira et al²³ 2000	3.5	Abdominal pain, distension	13cm×10cm× 10cm lobulated mass confined to the right ovary	Right oophorectomy, chemotherapy	Vincristine and actinomycin D	6.5 years	NED
Isaac et al²⁴ 2000	21	Menorrhagia, abd-ominal symptoms, palpable pelvic mass	Right orarian mul- tilocular mass, in diameter of 19 cm	RSO, wedge resection of the left ovary, che- motherapy	Bleomycin, etoposide, cisplatin, vincristine and actinomycin D	6 months	NED
Oner et al²² 2002	3.5	Abdominal pain and vomiting	13cm×10cm× 6.5cm tuboovarian mass	Debulking, LSO, appendectomy and partial omentectomy, chemotherapy	Vincristine and actinomycin D	7 months	NED
Li et al²⁶ 2008	22	Abdominal disten-tion, abdominal pain, fever	Ovarian cystic mass, 18cm×14cm×3cm	Not stated	Not stated	Not stated	Not stated

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