Chinese Medical Sciences Journal ›› 2017, Vol. 32 ›› Issue (4): 269-273.doi: 10.24920/J1001-9294.2017.049

• 病例报告 • 上一篇    下一篇

双眼脉络膜阻塞继发于抗磷脂综合征合并系统性红斑狼疮

张扬, 张顺华, 卞爱玲, 陈有信*()   

  1. 中国医学科学院 北京协和医学院 北京协和医院眼科,北京, 100730
  • 收稿日期:2016-11-18 出版日期:2017-12-30 发布日期:2017-12-30
  • 通讯作者: 陈有信 E-mail:chenyouxinpumch@163.com

Bilateral Choroidal Occlusion in Antiphospholipid Syndrome Associated with Systemic Lupus Erythematosus

Zhang Yang, Zhang Shunhua, Bian Ailing, Chen Youxin*()   

  1. Department of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China
  • Received:2016-11-18 Published:2017-12-30 Online:2017-12-30
  • Contact: Chen Youxin E-mail:chenyouxinpumch@163.com

摘要:

本文报告了1例合并系统性红斑狼疮(SLE)的抗磷脂综合征(APS)患者,并发双眼脉络膜阻塞的罕见病例。患者女性,24岁,双眼视力快速进行性下降,经眼科检查诊断为双眼脉络膜阻塞。影像检查发现腹主动脉血栓,双侧髂动脉阻塞。患者伴有多次流产病史。给予患者糖皮质激素、免疫抑制剂及抗凝联合治疗后,患者视功能有所改善。合并系统性红斑狼疮的抗磷脂综合征患者眼部有血栓形成的风险,可累及不同管径的眼部血管,包括视网膜动静脉。本病例提示眼科、风湿科医师,SLE相关的APS患者发生血管栓塞可以累及脉络膜,甚至双眼同时发病,导致视功能的损害,需早期积极的治疗。

关键词: 抗心磷脂抗体, 抗磷脂抗体, 脉络膜血管, 系统性红斑狼疮

Abstract:

This article reports a rare case of bilateral choroidal occlusion that occurred in a 24-year-old woman with antiphospholipid syndrome (APS) associated with systemic lupus erythematosus (SLE). This young lady concurred with aorta ventralis thrombosis and bilateral iliac artery occlusion when presented, and experienced a rapid deterioration of vision. She also has a history of recurrent miscarriage. Corticosteroid, immunosuppression and anticoagulation therapy were administered. Patients with APS associated with SLE are at risk for thrombotic phenomena, which may affect the ocular vessels of all sizes, including choroidal vessel. Our case alerts ophthalmologists and rheumatologists that bilateral choroidal occlusion may indeed be developed in patients with APS associated with SLE, and is a potential cause of visual morbidity.

Key words: anticardiolipin antibodies, antiphospholipid antibodies, choroidal vessels, systemic lupus erythematosus

补充说明: This article reports a rare case of bilateral choroidal occlusion that occurred in a 24-year-old#br# woman with antiphospholipid syndrome (APS) associated with systemic lupus erythematosus (SLE), which alerts ophthalmologists and rheumatologists that bilateral choroidal occlusion may indeed occurred in this special condition and cause visual morbidity.#br#

Copyright © 2018 Chinese Academy of Medical Sciences. All right reserved.
 
www.cmsj.cams.cn
京公安备110402430088 京ICP备06002729号-1  Powered by Magtech.

Supervised by National Health Commission of the People's Republic of China

9 Dongdan Santiao, Dongcheng district, Beijing, 100730 China

Tel: 86-10-65105897  Fax:86-10-65133074 

E-mail: cmsj@cams.cn  www.cmsj.cams.cn

Copyright © 2018 Chinese Academy of Medical Sciences

All right reserved.

京公安备110402430088  京ICP备06002729号-1