Sutureless Intestinal Anastomosis with a Novel Device of Magnetic Compression Anastomosis△

doi:10.1016/S1001-9294(11)60046-1

Chinese Medical Sciences Journal ›› 2011, Vol. 26 ›› Issue (3): 182-189.doi: 10.1016/S1001-9294(11)60046-1

• Original Article • 上一篇下一篇

Sutureless Intestinal Anastomosis with a Novel Device of Magnetic Compression Anastomosis^△

Chao Fan, Jia Ma, Hong-ke Zhang, Rui Gao, Jian-hui Li, Liang Yu, Zheng Wu, Yi Lv^*

Department of Hepatobiliary Surgery, the First Affiliated Hospital, Medical School of Xi’an Jiaotong University, Xi’an 710061, China

出版日期:2011-09-24 发布日期:2011-09-24
通讯作者: Support by the National Natural Science Foundation of China (30830099). E-mail:luyi169@ 126.com

Sutureless Intestinal Anastomosis with a Novel Device of Magnetic Compression Anastomosis

Chao Fan, Jia Ma, Hong-ke Zhang, Rui Gao, Jian-hui Li, Liang Yu, Zheng Wu, Yi Lv^*

Department of Hepatobiliary Surgery, the First Affiliated Hospital, Medical School of Xi’an Jiaotong University, Xi’an 710061, China

Online:2011-09-24 Published:2011-09-24
Contact: Support by the National Natural Science Foundation of China (30830099). E-mail:luyi169@ 126.com

摘要/Abstract

摘要： Objective To explore the feasibility and efficiency of a novel magnetic compression anastomats (MCAs) in intestinal anastomosis.
Methods A total of 36 male mongrel canines underwent intestinal anastomosis using traditional hand-sewn (n=18) or a novel MCAs (n=18). We compared the anastomosis time, postoperative complica-tions, bursting strength of anastomoses, gross appearance, and pathology between two groups at each time- point of follow-up.
Results The mean anastomosis time with MCAs was significantly less than that with hand-sewn (8.50±1.95 vs. 31.1±4.32 minutes, P<0.001). The blood stools and intussusceptions occurred in both groups during follow-up period. Only 1 mongrel canine receiving intestinal anastomosis by MCAs experi-enced anastomotic leakage. The average bursting pressure of anastomoses obtained from mongrel canines undergoing intestinal anastomosis by MCAs was significantly higher than that by traditional hand-sewn at 1 week’s follow-up time (P<0.05). Gross appearance of the anastomoses constructed by MCAs was relatively smoother and flatter. Pathological evalution of anastomoses revealed that general inflammation was greater in hand-sewn anastomoses than magnetic anastomosis.
Conclusion The magnetic compression anastomat is a safe and effective device of sutureless intesti-nal anastomosis in canine models.

关键词: magnetic compression anastomosis, bursting strength, foreign body reaction

Abstract: Objective To explore the feasibility and efficiency of a novel magnetic compression anastomats (MCAs) in intestinal anastomosis.
Methods A total of 36 male mongrel canines underwent intestinal anastomosis using traditional hand-sewn (n=18) or a novel MCAs (n=18). We compared the anastomosis time, postoperative complica-tions, bursting strength of anastomoses, gross appearance, and pathology between two groups at each time- point of follow-up.
Results The mean anastomosis time with MCAs was significantly less than that with hand-sewn (8.50±1.95 vs. 31.1±4.32 minutes, P<0.001). The blood stools and intussusceptions occurred in both groups during follow-up period. Only 1 mongrel canine receiving intestinal anastomosis by MCAs experi-enced anastomotic leakage. The average bursting pressure of anastomoses obtained from mongrel canines undergoing intestinal anastomosis by MCAs was significantly higher than that by traditional hand-sewn at 1 week’s follow-up time (P<0.05). Gross appearance of the anastomoses constructed by MCAs was relatively smoother and flatter. Pathological evalution of anastomoses revealed that general inflammation was greater in hand-sewn anastomoses than magnetic anastomosis.
Conclusion The magnetic compression anastomat is a safe and effective device of sutureless intesti-nal anastomosis in canine models.

Key words: magnetic compression anastomosis, bursting strength, foreign body reaction

Chao Fan, Jia Ma, Hong-ke Zhang, Rui Gao, Jian-hui Li, Liang Yu, Zheng Wu, Yi Lv. Sutureless Intestinal Anastomosis with a Novel Device of Magnetic Compression Anastomosis[J].Chinese Medical Sciences Journal, 2011, 26(3): 182-189.

参考文献 17

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Sutureless Intestinal Anastomosis with a Novel Device of Magnetic Compression Anastomosis^△

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