Chinese Medical Sciences Journal ›› 2012, Vol. 27 ›› Issue (2): 115-120.

• Original Article • 上一篇    下一篇

Primary Meningeal Melanocytoma Located in Foramen Magnum: a Case Report and Review of the Literatures

Ming-chao Fan1,2, Jing-feng Wang1, Wei-wei Fu3, Ke Liu1, Lian-di Li1, and Peng Sun2*   

  1. 1Department of Neurosurgery Intensive Care Unit, 2Department of Neurosurgery, 3Department of Pathology, the Affiliated Hospital of Medical College, Qingdao University, Qingdao 266003, China
  • 收稿日期:2012-07-05 修回日期:2012-07-05 出版日期:2012-07-05 发布日期:2012-07-05
  • 作者简介:*Corresponding author Tel: 86-532-82912326, E-mail: fanmcchina@ 126.com

Primary Meningeal Melanocytoma Located in Foramen Magnum: a Case Report and Review of the Literatures

Ming-chao Fan1, 2, Jing-feng Wang1, Wei-wei Fu3, Ke Liu1, Lian-di Li1, and Peng Sun2*   

  1. 1Department of Neurosurgery Intensive Care Unit, 2Department of Neurosurgery, 3Department of Pathology, the Affiliated Hospital of Medical College, Qingdao University, Qingdao 266003, China
  • Received:2012-07-05 Revised:2012-07-05 Online:2012-07-05 Published:2012-07-05

摘要: LIMAS and Tio1 proposed the term meningeal melanocytoma first time in 1972 to describe a primary melanotic tumor of the leptomeninges with prolonged clinical course and benign histology. Meningeal melanocytoma of the central nervous system is rare and benign primary meningeal melanocytoma (PMM) is more exceptional, and also less usual than the malignant types.2 This rare tumor falls under the subclassification of primary melanocytic lesions in the World Health Organization’s classification of central nervous system tumors.3 PMM located in the foramen magnum region is an unusual cause of bulbus medullae and fourth ventricle compression. Here we report a 48-year-old man with a PMM which is located in the foramen magnum inducing supratentorial obstructive hydrocephalus.

关键词: foramen magnum, meningeal melanocytoma, histopathology, neuroimaging, obstructive hydrocephalus

Abstract: LIMAS and Tio1 proposed the term meningeal melanocytoma first time in 1972 to describe a primary melanotic tumor of the leptomeninges with prolonged clinical course and benign histology. Meningeal melanocytoma of the central nervous system is rare and benign primary meningeal melanocytoma (PMM) is more exceptional, and also less usual than the malignant types.2 This rare tumor falls under the subclassification of primary melanocytic lesions in the World Health Organization’s classification of central nervous system tumors.3 PMM located in the foramen magnum region is an unusual cause of bulbus medullae and fourth ventricle compression. Here we report a 48-year-old man with a PMM which is located in the foramen magnum inducing supratentorial obstructive hydrocephalus.

Key words: foramen magnum, meningeal melanocytoma, histopathology, neuroimaging, obstructive hydrocephalus

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