磁共振场强对脑T2-FLAIR图像纹理特征影响的初步研究

doi:10.24920/003713

摘要/Abstract

摘要：

目的探讨磁共振场强对脑部T2液体衰减反转恢复（T2-FLAIR）图像纹理特征的影响。
方法我们分别采用MR-1.5T和MR-3.0T扫描对30例脑白质病变患者进行了脑部三维T2-FLAIR成像。基于ImageJ软件采用感兴趣法对白质病变区和正常白质区进行测量,并比较了MR-1.5T和MR-3.0T扫描图像所获得的纹理参数。直方图纹理特征包括平均信号强度、偏度和峰度,灰度共生矩阵纹理特征包括角二阶矩、对比度、自相关、逆差矩和熵。
结果不论是脑白质病变区还是正常脑白质,由MR-1.5T扫描获得的平均信号强度值均显著低于MR-3.0T扫描的结果（P<0.001）,而在两种场强下偏度和峰度的差异无显著性（P>0.05）;此外,由MR-1.5T扫描获得的角二阶矩、自相关和逆差距均显著低于MR-3.0T扫描的结果（P<0.001）,而对比度和熵均显著高于MR-3.0T扫描的结果（P<0.001）。
结论 MR场强对MR-1.5T和MR-3.0T系统所生成的脑部T2-FLAIR图像的直方图纹理无显著影响,而对灰度共生矩阵纹理特征有显著影响,此结果提示应谨慎解释不同MR场强下T2-FLAIR图像的纹理结果。

关键词: 磁共振成像, 场强, 液体衰减翻转恢复, 白质, 纹理特征

Abstract:

Objective To investigate effect of MR field strength on texture features of cerebral T2 fluid attenuated inversion recovery (T2-FLAIR) images.
Methods We acquired cerebral 3D T2-FLAIR images of thirty patients who were diagnosed with ischemic white matter lesion (WML) with MR-1.5T and MR-3.0T scanners. Histogram texture features which included mean signal intensity (Mean), Skewness and Kurtosis, and gray level co-occurrence matrix (GLCM) texture features which included angular second moment (ASM), Contrast, Correlation, Inverse difference moment (IDM) and Entropy, of regions of interest located in the area of WML and normal white matter (NWM) were measured by ImageJ software. The texture parameters acquired with MR-1.5T scanning were compared with MR-3.0T scanning.
Results The Mean of both WML and NWM obtained with MR-1.5T scanning was significantly lower than that acquired with MR-3.0T (P<0.001), while Skewness and Kurtosis between MR-1.5T and MR-3.0T scanning showed no significant difference (P>0.05). ASM, Correlation and IDM of both WML and NWM acquired with MR-1.5T revealed significantly lower values than those with MR-3.0T (P<0.001), while Contrast and Entropy acquired with MR-1.5T showed significantly higher values than those with MR-3.0T (P<0.001).
Conclusion MR field strength showed no significant effect on histogram textures, while had significant effect on GLCM texture features of cerebral T2-FLAIR images, which indicated that it should be cautious to explain the texture results acquired based on the different MR field strength.

Key words: magnetic resonance imaging, field strength, fluid attenuated inversion recovery, white matter, texture features

Wang Xuedan, Wang Shiwei, Wang Botao, Chen Zhiye. Effect of MR Field Strength on the Texture Features of Cerebral T2-FLAIR Images: A Pilot Study[J].Chinese Medical Sciences Journal, 2020, 35(3): 248-253.

图/表 3

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Groups	Histogram			GLCM
Groups	Mean^b	Skewness^a	Kurtosis^a	ASM^b	Contrast^b	Correlation^a	IDM^a	Entropy^a
1.5T	469.906 (105.600)	-0.252±0.570	-0.358±0.790	0.008 (0.000)	23.975 (26.350)	0.009±0.005	0.233±0.079	4.956±0.320
3.0T	1894.024 (307.910)	-0.394±0.620	-0.348±1.040	0.015 (0.010)	8.150 (7.400)	0.032±0.020	0.380±0.099	4.550±0.444
t/Z value	4.762	1.162	1.059	4.179	3.898	6.497	8.385	4.966
P value	<0.001	0.245	0.289	<0.001	<0.001	<0.001	<0.001	<0.001

Groups	Histogram			GLCM
Groups	Mean^a	Skewness^a	Kurtosis^b	ASM^b	Contrast^b	Correlation^b	IDM^a	Entropy^a
1.5T	234.898±26.870	0.086±0.553	-0.195 (1.330)	0.011 (0.010)	10.252 (9.260)	0.023 (0.020)	0.306±0.077	4.710±0.450
3.0T	1243.273±130.388	-0.031±0.434	-0.354 (0.760)	0.025 (0.010)	2.916 (2.530)	0.089 (0.080)	0.487±0.091	3.995±0.477
t/Z value	45.400	1.089	1.532	4.683	4.782	4.710	10.476	9.754
P value	<0.001	0.285	0.125	<0.001	<0.001	<0.001	<0.001	<0.001

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