Chinese Medical Sciences Journal ›› 2014, Vol. 29 ›› Issue (1): 51-54.doi: 10.1016/S1001-9294(14)60025-0

• 论著 • 上一篇    下一篇

Bloodstream Infection with Carbapenem-resistant Klebsiella Pneumoniae and Multidrug-resistant Acinetobacter Baumannii: a Case Report

Hong-min Zhang,Da-wei Liu*,Xiao-ting Wang,Yun Long,Huan Chen   

  1. Department of Critical Care Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China
  • 收稿日期:2013-07-24 出版日期:2014-03-31 发布日期:2014-03-31

Bloodstream Infection with Carbapenem-resistant Klebsiella Pneumoniae and Multidrug-resistant Acinetobacter Baumannii: a Case Report

Hong-min Zhang,Da-wei Liu*,Xiao-ting Wang,Yun Long,Huan Chen   

  1. Department of Critical Care Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China
  • Received:2013-07-24 Published:2014-03-31 Online:2014-03-31
  • Contact: Tel:86-10-69152305, E-mail:dwliu@medmail.com.cn

摘要:

IN the presence of septic shock, every hour in delaying the administration of effective antibiotics is associated with a measurable increase in mortality. This is especially true for neutropenic patients with septic shock.1 As there is a higher incidence of involving multi-drug resistant pathogens for neutropenic patients, the decision on antibiotics regime remains a challenge for physicians.2 Immunosuppression and previous antibacterial use are factors that promote the spread of multi-drug resistant pathogens, and the possibility of co-existing multi-drug resistant pathogens should be suspected when treating patients with these risk factors who developed refractory shock. Here we present a case with neutropenic fever and refractory shock whose blood culture yielded multi-drug resistant Acinetobacter baumannii and carbapenem- resistant Klebsiella pneumoniae.

关键词: bloodstream infection, neutropenic fever, carbapenem-resistant Klebsiella pneumoniae, Acinetobacter baumannii

Abstract:

IN the presence of septic shock, every hour in delaying the administration of effective antibiotics is associated with a measurable increase in mortality. This is especially true for neutropenic patients with septic shock.1 As there is a higher incidence of involving multi-drug resistant pathogens for neutropenic patients, the decision on antibiotics regime remains a challenge for physicians.2 Immunosuppression and previous antibacterial use are factors that promote the spread of multi-drug resistant pathogens, and the possibility of co-existing multi-drug resistant pathogens should be suspected when treating patients with these risk factors who developed refractory shock. Here we present a case with neutropenic fever and refractory shock whose blood culture yielded multi-drug resistant Acinetobacter baumannii and carbapenem- resistant Klebsiella pneumoniae.

Key words: bloodstream infection, neutropenic fever, carbapenem-resistant Klebsiella pneumoniae, Acinetobacter baumannii

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