Chinese Medical Sciences Journal ›› 2019, Vol. 34 ›› Issue (3): 226-229.doi: 10.24920/003478

• 病例报告 • 上一篇    下一篇



  1. 1 暨南大学附属广州市红十字会医院 重症医学科,广州 510220
    2 暨南大学附属广州市红十字会医院 营养科,广州 510220
  • 收稿日期:2019-06-18 出版日期:2019-09-30 发布日期:2019-07-02
  • 通讯作者: 韦建瑞

Management of an Adult with Goodpasture’s Syndrome Following Brain Trauma with Extracorporeal Membrane Oxygenation: A Case Report

Wang Shan1,Yin Haiyan1,Zhu Youfeng1,Tao Pei1,Zhang Rui1,Ma Yonghui1,Wei Jianrui2,*()   

  1. 1 Department of Intensive Care Unit, Guangzhou Red Cross Hospital, Medical College, Jinan University, Guangzhou 510220, China
    2 Institute of Clinical Nutrition, Guangzhou Red Cross Hospital, Medical College, Jinan University, Guangzhou 510220, China
  • Received:2019-06-18 Published:2019-09-30 Online:2019-07-02
  • Contact: Wei Jianrui



关键词: 体外膜肺氧合, 肺出血, 肺出血肾炎综合征, 抗肾小球基底膜抗体


A 22-year-old man suffered from acute pulmonary hemorrhage and deteriorated renal function occurred within 3 days after traumatic brain injury. Mechanical ventilation cannot correct his severe hypoxemia, therefore, venoarterial extracorporeal membrane oxygenation (VA-ECMO) support was initiated and finally resolved his hypoxemia. Concomitantly, continuous renal replacement therapy was performed to improve his kidney function. Although no anti-glomerular basement membrane (anti-GBM) antibody was detected in serum, Goodpasture’s syndrome was considered. After treated with methylprednisolone pulse therapy and plasmapheresis, his renal function was significantly improved. ECMO was eventually discontinued after 60 hours of treatment and extubated on day 10. He was discharged home with normal pulmonary and renal functions.

Key words: extracorporeal membrane oxygenation, pulmonary hemorrhage, Goodpasture's Syndrome, anti-glomerular basement membrane antibody

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