Chinese Medical Sciences Journal ›› 2019, Vol. 34 ›› Issue (4): 297-299.doi: 10.24920/003536

• 病例报告 • 上一篇    

EB病毒感染后瑞氏综合征伴多器官功能障碍的一例重症病例

刘秉楠,齐莹()   

  1. 中国医科大学附属盛京医院病毒研究室,沈阳,110004 中国
  • 收稿日期:2018-11-12 接受日期:2019-04-15 出版日期:2019-12-31 发布日期:2019-12-06
  • 通讯作者: 齐莹 E-mail:qiyingying163@163.com

A Severe Case of Reye’s Syndrome with Multiorgan Dysfunction after Epstein-Barr Virus Infection

Liu Bingnan,Qi Ying()   

  1. Virology Lab, the Shengjing Hospital of China Medical University, Shenyang, 110004 China
  • Received:2018-11-12 Accepted:2019-04-15 Published:2019-12-31 Online:2019-12-06
  • Contact: Qi Ying E-mail:qiyingying163@163.com

摘要:

一名20个月大的男婴在爱泼斯坦-巴尔病毒(Epstein-Barr virus,EBV)感染后进展为瑞氏综合征并伴有多器官功能障碍。患儿同时罹患急性肝衰竭,危及生命的脑水肿,严重的弥散性血管内凝血以及心肌受累。EBV感染在本例加重了瑞氏综合征的疾病进展。患儿尽管接受了全面的支持和对症治疗, 仍未免于死亡。本文报告的重症病例提示儿科医生应注意重度EBV感染的多器官受累。

关键词: 爱泼斯坦-巴尔病毒, 瑞氏综合征, 多器官功能障碍

Abstract:

A 20-month-old male infant with multiorgan dysfunction after Epstein-Barr virus (EBV) infection developed Reye’s syndrome. He also suffered from acute liver failure, life-threatening cerebral edema, severe disseminated intravascular coagulation (DIC), and myocardial involvement. EBV infection aggravated the progress of Reye’s syndrome, leading to death despite full supportive and symptomatic therapy. This critical case suggested that pediatricians should pay attention to multiorgan involvement of severe EBV infection.

Key words: Epstein-Barr virus, Reye’s syndrome;, multiorgan dysfunction

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