Chinese Medical Sciences Journal ›› 2013, Vol. 28 ›› Issue (2): 107-112.doi: 10.1016/S1001-9294(13)60031-0

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Standard Versus Extended Pancreaticoduodenectomy in Treating Adenocarcinoma of the Head of the Pancreas

Jun Gong1, 2, Gang Mai2, Zhen-jiang Zheng2, Guang-ming Xiang2, Wei-ming Hu2, Bo-le Tian2, Zhao-da Zhang2, and Xu-bao Liu2*   

  1. 1Department of Hepatobiliary and Pancreatic Surgery, Sichuan Academy of Medical Science and Sichuan Provincial People’s Hospital, Chengdu 610072, China
    2Department of Hepatobiliary and Pancreatic Surgery, West China Hospital, Sichuan University, Chengdu 610041, China
  • Received:2012-10-16 Online:2013-06-26 Published:2013-06-26
  • Contact: 86-28-85422474,Fax:86-28-85422476,E-mail:xbliu@medmail.com.cn

Abstract:

Between January 1994 and December 2011, 165 patients with biopsy-proven adenocarcinoma of the pancreatic head were treated in West China Hospital, among whom 93 underwent SPD and 72 had EPD. Complications and survival after the surgery were analyzed retrospectively.

The median operation time of the EPD group was longer compared with the SPD group (375 minutes vs.310 minutes, P<0.01), the volume of blood transfusion was larger (700 mL vs.400 mL, P<0.05), while the median hospital stay (13.5 days vs.12 days, P= 0.79) and the total complication rates were comparable (34.7% vs.32.4%, P=0.93). The total recurrence rates of the SPD and EPD groups were not significantly different (52.7% vs. 43.1%, P=0.83). No significant differences were found between the SPD and EPD groups in 1-year (81.7% vs. 86.1%), 3-year (38.7% vs. 43.1%), 5-year (16.7% vs. 19.4%), and median survivals (19.8 months vs. 23.2 months, P= 0.52).

The postoperative complications and survival donot differ significantly between SPD and EPD.

Key words: pancreas, cancer, pancreaticoduodenectomy, standard resection, extended resection

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