Chinese Medical Sciences Journal ›› 2021, Vol. 36 ›› Issue (1): 72-77.doi: 10.24920/003682
• Case Report • Previous Articles
Yanjie Cao1, Jingqi Duan1, *(), Lifang Liu1, Xuan Wei1, Li Ren2, Lanning Zhang1, Wei Zhang1
Received:
2019-11-12
Accepted:
2020-05-21
Published:
2021-03-31
Contact:
Jingqi Duan
E-mail:18610089727@163.com
Yanjie Cao,Jingqi Duan,Lifang Liu,Xuan Wei,Li Ren,Lanning Zhang,Wei Zhang. Individualized Treatment and Palliative Care for A 90-Year-Old Patient with Primary Gastric Diffuse Large-B Cell Lymphoma: 4 Year Follow-up and Inspiration[J].Chinese Medical Sciences Journal, 2021, 36(1): 72-77.
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Table 1
Nutrition-related laboratory indexes at different time of a very elderly patient with primary gastric diffuse large B-cell lymphoma"
Laboratory indexes | On admission (2016.4) | Pylorus obstruction (2016.9) | Current (2020.4) |
---|---|---|---|
Weight (kg) | 94 | 70 | 75 |
BMI (kg/m2) | 31.4 | 23.4 | 25.1 |
Red blood cells(×1012/L) | 2.7 | 2.7 | 2.6 |
Fecal occult blood testing | + | ± | - |
Hemoglobin (g/dL) | 8.4 | 9.0 | 9.4 |
Serum creatinine (μmol/L) | 126 | 123 | 102 |
eGFR (mL/min·1.73m2) | 49.6 | 51.1 | 62.8 |
Alanine aminotransferase (U/L) | 9 | 10 | 9 |
Aspartate aminotransaminase (U/L) | 22 | 19 | 21 |
Total protein(g/L) | 55.5 | 49.5 | 54.9 |
Pre-albumin (mg/L) | 248 | 193 | 188 |
Albumin (g/L) | 36.5 | 32.4 | 36.2 |
Total cholesterol(mmol/L) | 4.6 | 3.0 | 3.7 |
Low density lipoprotein (mmol/L) | 3.2 | 1.9 | 2.6 |
Triglycerides (mmol/L) | 0.9 | 1.3 | 1.4 |
Figure 1.
The PET-CT images detecting a gastric mass of a 90-year-old man. (A) Increased up-take of a mass at gastric antrum (white arrow), SUVMAX =3.4, which demonstrated pathologically as primary gastric diffuse large B-cell lymphoma; (B) follow up PET/CT showing decreased metabolism of the gastric antral mass, SUVMAX = 1.8, no metastatic lymphadenopathy observed."
Figure 2.
Endoscopic, histopathological and immunohistochemistry findings of a primary gastric diffuse large B cell lymphoma of a 90-year-old man. (A) Endoscopy revealed an ulcerative mass of the gastric antrum. The mucosal tissue was hard and easily to bleed. (B) Histopathological finding showing large-sized atypical lymphoma cells with minimal cytoplasm arrayed irregularly with expansive appearance, consistent with gastric large B-cell lymphoma (×200); (C) Immunohistochemical staining demonstrated CD20 positive cells and the diagnosis of diffuse large B-cell lymphoma ( ×200)"
1. |
Koch P, del Valle F, Berdel WE, et al. Primary gastrointestinal non-Hodgkin’s lymphoma: I. Anatomic and histologic distribution, clinical features, and survival data of 371 patients registered in the German Multicenter Study GITNHL 01/92. J Clin Oncol 2001; 19(18):3874-83. doi: 10.1200/JCO.2001.19.18.3874.
doi: 10.1200/JCO.2001.19.18.3874 pmid: 11559725 |
2. |
Yang QP, Zhang WY, Yu JB, et al. Subtype distribution of lymphomas in Southwest China: Analysis of 6,382 cases using WHO classification in a single institution. Diagn Pathol 2011; 6:77. doi: 10.1186/1746-1596-6-77.
doi: 10.1186/1746-1596-6-77 pmid: 21854649 |
3. |
Sohn BS, Kim SM, Yoon DH, et al. The comparison between CHOP and R-CHOP in primary gastric diffuse large B cell lymphoma. Ann Hematol 2012; 91:1731-9. doi: 10.1007/s00277-012-1512-4.
doi: 10.1007/s00277-012-1512-4 pmid: 22752193 |
4. |
Naruhiko I, Brian DB, Paul FM. Multimodality treatment of gastric lymphoma. Surg Clin N Am 2017; 97(2):405-20. doi: 10.1016/j.suc.2016.11.012.
doi: 10.1016/j.suc.2016.11.012 pmid: 28325194 |
5. |
Peyrade F, Jardin F, Thieblemont C, et al. Attenuated immunochemotherapy regimen (R-mini CHOP) in elderly patients older than 80 years with diffuse large B-cell lymphoma: a multicentre, single-arm, phase 2 trial. Lancet Oncol 2011; 12(5):460-8. doi: 10.1016/S1470-2045(11)70069-9.
doi: 10.1016/S1470-2045(11)70069-9 pmid: 21482186 |
6. |
Miyata Y, Saito AM, Yano T, et al. R-mini CHP in ≥ 80-year-old patients with diffuse large B-cell lymphoma: a multicenter, open-label, single-arm phase II trial protocol. Acta Med Okayama 2018; 72(3):315-8. doi: 10.18926/AMO/56079.
doi: 10.18926/AMO/56079 pmid: 29926011 |
7. |
Rohatiner A, d’Amore F, Coiffier B, et al. Report on a workshop convened to discuss the pathological and staging classifications of gastrointestinal tract lymphoma. Ann Oncol 1994; 5(5):397-400. doi: 10.1093/oxfordjournals.annonc.a058869.
doi: 10.1093/oxfordjournals.annonc.a058869 pmid: 8075046 |
8. |
Shipp MA, Harrington DP, Anderson JR, et al. A predictive model for aggressive non-Hodgkin lymphoma. N Engl J Med 1993; 329(14):987-94. doi: 10.1056/NEJM199309303291402.
doi: 10.1056/NEJM199309303291402 pmid: 8141877 |
9. |
Thieblemont C, Coiffier B. Lymphoma in older patients. J Clin Oncol 2007; 25(14):1916-23. doi: 10.1200/JCO.2006.10.5957.
doi: 10.1200/JCO.2006.10.5957 pmid: 17488991 |
10. |
Corazzelli G, Frigeri F, Arcamone M, et al. Biweekly rituximab, cyclophosphamide, vincristine, nonpegylated liposome-encapsulated doxorubicin and prednisone(R-COMP-14) in elderly patients with poor-risk diffuse large B-cell lymphoma and moderate to high ‘life threat’ impact cardiopathy. Br J Haematol 2011; 154(5):579-89. doi: 10.1111/j.1365-2141.2011.08786.x.
pmid: 21707585 |
11. |
Vitolo U, Seymour JF, Martelli M, et al. Extranodal diffuse large B-cell lymphoma (DLBCL) and primary mediastinal B-cell lymphoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol 2016; 27(Suppl 5):v91-102. doi: 10.1093/annonc/mdw175.
doi: 10.1093/annonc/mdw175 pmid: 27377716 |
12. |
Held G, Murawski N, Ziepert M, et al. Role of radiotherapy to bulky disease in elderly patients with aggressive B-cell lymphoma. J Clin Oncol 2014; 32:1112-8. doi: 10.1200/JCO.2013.51.4505.
doi: 10.1200/JCO.2013.51.4505 pmid: 24493716 |
13. |
Vargo JA, Gill BS, Balasubramani GK, et al. Treatment selection and survival outcomes in early-stage diffuse large B-cell lymphoma: do we still need consolidative radiotherapy? J Clin Oncol 2015; 33(32):3710-7. doi: 10.1200/JCO.2015.61.7654.
doi: 10.1200/JCO.2015.61.7654 pmid: 26261253 |
14. | Liu X, Fang H, Tian Y, et al. Intensity modulated radiation therapy for early-stage primary gastric diffuse large B-cell lymphoma: dosimetric analysis, clinical outcome, and quality of life. Int J Radiation Oncol Biol Phys 2016; 95(2):712-20. doi: 10.1016/j.ijrobp.2016.01.027. |
15. |
Qu X, Jiang N, Ge N, et al. Physicians perception of palliative care consultation service in a major general hospital in China. Chin Med Sci J 2018; 33(4):228-33. doi: 10.24920/003515.
doi: 10.24920/003515 pmid: 30646986 |
16. |
Xiang Y, Ning X. Recognition of palliative care in Chinese clinicians: How they feel and what they know. Chin Med Sci J 2018; 33(4):221-7. doi: 10.24920/003509.
doi: 10.24920/003509 pmid: 30646985 |
17. |
Fulton JJ, Newins AR, Porter LS, et al. Psychotherapy targeting depression and anxiety for use in palliative care: a meta-analysis. J Palliat Med 2018; 21(7):1024-37. doi: 10.1089/jpm.2017.0576.
doi: 10.1089/jpm.2017.0576 pmid: 29676960 |
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