Chinese Medical Sciences Journal ›› 2023, Vol. 38 ›› Issue (1): 70-72.doi: 10.24920/004092

• Case Report • Previous Articles    

Blue Nevus Hidden within the Nevus of Ota

Xing Liu1, Hui-Ying Zheng1, Fu-Min Fang1, He-Dan Yang1, Hui Ding1, Yin Yang1, Yi-Ping Ge1, *(), Tong Lin2, *()   

  1. 1Department of Cosmetic Laser Surgery, Institute of Dermatology, Chinese Academy of Medical Sciences & Peking Union Medical College, Nanjing 210042, China
    2Jiangsu Key Laboratory of Molecular Biology for Skin Diseases and STIs, Institute of Dermatology, Chinese Academy of Medical Sciences & Peking Union Medical College, Nanjing 210042, China
  • Received:2022-04-02 Accepted:2022-07-28 Published:2023-03-31 Online:2023-02-02
  • Contact: Yi-Ping Ge,Tong Lin E-mail:gypfeng@hotmail.com;ddlin@hotmail.com

A 3-year-old boy presented with bluish patch and scattered blue spots on the left side of his face. After several sessions of laser treatment, the azury patch in the periorbital area became even darker. Histopathology showed many bipolar, pigment-laden dendritic cells scattered in the papillary and upper reticular dermis. Immunohistochemically, these cells were positive for S100, SOX-10, melan-A, P16, and HMB-45. The positive rate of Ki-67 was less than 5%. Finally, the lesion was diagnosed with nevus of Ota concurrent with common blue nevus. Therefore, for cases of the nevus of Ota with poor response to laser treatment, the possible coexisting diseases should be suspected.

Key words: nevus of Ota, blue nevus, laser therapy

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