病理性瘢痕血供及组织缺氧的研究进展

doi:10.24920/J1001-9294.2017.014

Abstract

Blood supply is believed to be an important aspect in the development of pathological scars. However, there are controversies about vascular distribution, vascular structure and blood flow in pathological scars. Additionally, hypoxic microenvironment plays an important role in the vascularization of pathological scar tissues, and hypoxic conditions can be reflected by metabolic indexes and some cytokines. Furthermore, the correlation between blood supply and tissue hypoxia is controversial. The aim of this article is to review the literature on the characteristics of blood supply and tissue hypoxia in pathological scars, from which we can see pathological scars have unique characteristics of blood supply that are closely associated with tissue hypoxia. Moreover, development in the treatment of pathological scars is herein reviewed.

Key words: pathological scar, hypertrophic scar, keloid, blood flow, hypoxia

Li Zifei, Liu Qingliang, Wang Xiaojun, Luan Jie. The Characteristics of Blood Supply and Tissue Hypoxia in Pathological Scars[J].Chinese Medical Sciences Journal, 2017, 32(2): 113-118.

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