Characteristics of PVT1 and Its Roles in Diseases△

doi:10.1016/S1001-9294(14)60077-8

Abstract

LONG non-coding RNAs (lncRNAs) are a class of RNAs whose transcripts are longer than 200 nt. These molecules do not encode proteins but have a structure resembling that of mRNA and show polyA tails and promoter structure through splicing. Most lncRNAs show a distinct spatial and temporal specificity during histological differentiation and development. Dynamic expression and different splicing methods may appear during the differentiation process.

Key words: long non-coding RNAs, plasmacytoma variant translocation 1 gene, expression, characteristics

Funding: Supported by Science and Technology Plan of Guangdong Provincial Department of Science and Technology (2011B031800012)

Li Wang, Jin-hua He, Ze-ping Han. Characteristics of PVT1 and Its Roles in Diseases[J].Chinese Medical Sciences Journal, 2014, 29(4): 236-238.

References 13

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