Chinese Medical Sciences Journal ›› 2022, Vol. 37 ›› Issue (4): 287-292.doi: 10.24920/004130
• Original Articles • Next Articles
Xue Zhang1, Lingeer Wu1, Huizhen Huang1, Yuelun Zhang2, Zhilong Lu1, Yajie Tian1, Le Shen1, *(), Yuguang Huang1
Received:
2022-06-23
Accepted:
2022-09-30
Published:
2022-12-31
Online:
2022-10-10
Contact:
Le Shen
E-mail:pumchshenle@163.com
Xue Zhang, Lingeer Wu, Huizhen Huang, Yuelun Zhang, Zhilong Lu, Yajie Tian, Le Shen, Yuguang Huang. Risk Factors for Anesthesia-Related Airway Patient Safety Incidents: A Single-Center Retrospective Case-Control Analysis from 2009 to 2022[J].Chinese Medical Sciences Journal, 2022, 37(4): 287-292.
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Figure 1.
Enrollment and classification of airway-related PSIs. This figure shows the classification of airway-related PSIs reported by anesthesiologists during September 2009 to May 2022 as well as the number of cases in each category. PSI: patient safety incident; NPPE: negative pressure pulmonary edema."
Table 1.
Risk factors associated with airway-related PSI occurrence found via univariable analysis"
Risk factors | Airway PSI group (n = 170) | Control group (n = 170) | Mean difference/OR (95%CI) | P value |
---|---|---|---|---|
Age (yrs, mean±SD) | 54.63±??.49 | 52.63±??.52 | 2.00 (-1.10 to 5.10) | 0.206 |
Height (cm, mean±SD) | 165.27±8.62 | 165.80±?.47 | -0.53 (-2.29 to 1.24) | 0.559 |
Weight (kg, mean±SD) | 66.13±3.19 | 64.75±?1.72 | 1.38 (-1.29 to 4.04) | 0.310 |
BMI (kg/m2, mean±SD) | 24.09±?.25 | 23.54±?.41 | 0.55 (-0.29 to 1.40) | 0.197 |
ASA PS (n) | ||||
Ⅰ | 24 | 46 | Reference | |
Ⅱ | 112 | 110 | 1.59 (0.86 to 2.93) | 0.137 |
Ⅲ | 34 | 14 | 3.40 (1.42 to 8.11) | 0.006 |
Preoperative comorbidities (n) | ||||
Hypertension | 53 | 38 | 1.57 (0.97 to 2.56) | 0.066 |
Diabetes | 26 | 18 | 1.53 (0.80 to 2.90) | 0.196 |
Smoking history (n) | 44 | 42 | 1.06 (0.65 to 1.74) | 0.803 |
Drinking history (n) | 25 | 25 | 1.00 (0.55 to 1.82) | 1.000 |
Preoperative laboratory test indices (mean±SD) | ||||
WBC (×109/L) | 6.55±1.96 | 6.52±2.47 | 0.03 (-0.45 to 0.50) | 0.906 |
NEUT (%) | 62.03±10.39 | 61.06±10.64 | 0.97 (-1.28 to 3.22) | 0.396 |
LY (%) | 28.12±9.32 | 29.23±9.42 | -1.11 (-3.11 to 0.89) | 0.276 |
HGB (g/L) | 132.19±25.22 | 135.65±18.54 | -3.46 (-8.19 to 1.28) | 0.152 |
Hct (%) | 39.84±5.51 | 40.27±4.97 | -0.43 (-1.56 to 0.69) | 0.446 |
PLT (×109/L) | 241.13±80.60 | 240.30±70.94 | 0.83 (-15.40 to 17.06) | 0.920 |
ALT (U/L) | 30.90±49.79 | 27.17±47.00 | 3.73 (-6.62 to 14.07) | 0.479 |
Alb (g/L) | 41.65±4.96 | 42.98±3.96 | -1.32 (-2.29 to -0.36) | 0.007 |
Serum Cr (μmol/L) | 69.10±21.48 | 67.50±15.94 | 1.60 (-2.44 to 5.65) | 0.437 |
PT (s) | 11.83±0.99 | 11.64±1.14 | 0.18 (-0.04 to 0.41) | 0.114 |
APTT (s) | 27.96±3.96 | 27.05±3.25 | 1.03 (-0.01 to 2.07) | 0.051 |
Fibrinogen (g/L) | 3.28±1.26 | 2.99±0.89 | 0.29 (0.05 to 0.52) | 0.016 |
Glucose (mmol/L) | 5.70±1.28 | 5.64±1.50 | 0.05 (-0.25 to 0.35) | 0.722 |
Table 2.
Risk factors associated with airway-related PSI occurrence identified via multivariable analysis"
Groups | ASA PS (n) | Age (yrs) | Alb (g/L) | Fibrinogen (g/L) | BMI (kg/m2) | Hypertension (n) | ||
---|---|---|---|---|---|---|---|---|
Ⅰ | Ⅱ | Ⅲ | ||||||
Control group | 46 | 110 | 14 | 52.63±13.52 | 42.98±3.96 | 2.99±0.89 | 23.54±3.41 | 38 |
Airway PSI group | 24 | 112 | 34 | 54.63±15.49 | 41.65±4.96 | 3.28±1.26 | 24.09±4.25 | 53 |
OR (95%CI) | Reference | 1.65 (0.88 to 3.08) | 3.50 (1.45 to 8.42) | 1.00 (0.98 to 1.01) | 0.97 (0.91 to 1.02) | 1.16 (0.92 to 1.47) | 1.04 (0.98 to 1.11) | 1.16 (0.66 to 2.05) |
P value | 0.020 | 0.627 | 0.208 | 0.213 | 0.202 | 0.603 |
Table 3.
Prognosis of patients with airway incidents (n = 170)"
Groups | Extubation time (d, mean±SD) | ICU LOS (d, mean±SD) | Post-operative LOS (d, mean±SD) | In-hospital LOS (d, mean±SD) | Complications (n) | |
---|---|---|---|---|---|---|
Pulmonary infection | MACE | |||||
Control group | 0.16±0.77 | 0.19±0.84 | 7.59±10.76 | 11.62±11.88 | 4 | 1 |
Airway PSI group | 0.72±1.56 | 1.63±5.71 | 10.56±13.09 | 14.99±15.18 | 11 | 7 |
Mean difference/OR (95%CI) | 0.55 (0.29 to 0.82) | 1.44 (0.57 to 2.32) | 2.97 (0.41 to 5.53) | 3.37 (0.46 to 6.27) | 2.87 (0.90 to 9.020) | 7.26 (0.88 to 59.64) |
P value | < 0.001 | 0.001 | 0.023 | 0.024 | 0.065 | 0.067 |
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