Chinese Medical Sciences Journal ›› 2013, Vol. 28 ›› Issue (2): 122-123.doi: 10.1016/S1001-9294(13)60034-6

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Characteristics of Antisense Non-coding RNA in the INK4 Locus and Its Roles in Disease

Jin-hua He and Yu-guang Li*   

  1. Department of Laboratory, Panyu Central Hospital, Guangzhou 511400, China
  • Received:2013-01-02 Online:2013-06-26 Published:2013-06-26
  • Contact: 86-20-34858853,E-mail:lyg0005F;py@126.com

Abstract:

With the development of genome-wide sequencing technology, 195 types of functional long non-coding RNAs (lncRNAs) have so far been found, and their cellular roles are gradually being revealed. Now lncRNAs have become a hotspot in the life science. These small molecules exist in almost all higher eukaryotes, and have very important regulatory roles in these organisms. This review briefly summarizes recent progress in researches on antisense non-coding RNA in the INK4 locus.

Key words: long non-coding RNAs, antisense non-coding RNA in the INK4 locus, expression

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