Chinese Medical Sciences Journal ›› 2015, Vol. 30 ›› Issue (2): 65-69.doi: 10.1016/S1001-9294(15)30013-4

• Original Articles •     Next Articles

Relationship between Ulcerative Colitis and Lung Injuries

Zhi-peng Tang1, Jia-wei Wu1, Yan-cheng Dai1, *, Ya-li Zhang1, Rong-rong Bi2   

  1. 1Department of Gastroenterology, Institute of Digestive Diseases, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China;
    2Department of Lung Function Laboratory, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China
  • Received:2014-11-24 Published:2015-07-02 Online:2015-07-02
  • Contact: *Corresponding author Tel: 86-21-64385700-3923,

Objective To explore the relationship between ulcerative colitis (UC) and lung injuries by assessing their clinical manifestations and characteristics.Methods From July 2009 to April 2012, 91 UC patients presenting to Longhua Hospital who met the established inclusion and exclusion criteria were enrolled in this retrospective study. According to the scores of disease activity index, the patients were divided into the mild, moderate, and severe groups. Meanwhile, the records of pulmonary symptoms, chest X-ray image, and pulmonary function were reviewed.Results Sixty-eight (74.7%) patients had at least 1 pulmonary symptom, such as cough (38.5%), shortness of breath (27.5%), and expectoration (17.6%). And 77 (84.6%) had at least 1 ventilation abnormality. Vital capacity value was significantly lower in the severe group than that in the mild group (91.82%±10.38% vs. 98.92%±12.12%, P<0.05).Conclusions Lung injury is a common extraintestinal complication of UC. According to the theory in Traditional Chinese Medicine that the lung and large intestine are related, both the lungs and large intestine should be treated simultaneously.

Key words: ulcerative colitis, lung injury, Traditional Chinese Medicine


△Supported by the New Project of Traditional Chinese Medicine of Shanghai Health and Family Planning Commission for the next three years (LH02.28.006)

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