Chinese Medical Sciences Journal ›› 2019, Vol. 34 ›› Issue (1): 55-59.doi: 10.24920/003460

• Case Reports • Previous Articles     Next Articles

Bilateral Peripheral Facial Paralysis Combined with HIV Meningitis During Acute HIV-1 Infection: A Case Report

Wu Yan1, 2, Song Ge2, Wei Chunbo1, Lun Wenhui1, 2, *()   

  1. 1 Department of Dermatology and Venereology, Beijing Ditan Hospital Affiliated to Capital Medical University, Beijing 100015, China
    2 Infectious Disease Center, Peking University Ditan Teaching Hospital, Beijing 100015, China
  • Received:2018-02-02 Revised:2019-02-22 Published:2019-03-30 Online:2019-04-08
  • Contact: Lun Wenhui

Here we reported a Chinese case of bilateral peripheral facial paralysis (PFP) in human immunodeficiency virusc (HIV) infected population. A 38-year-old homosexual male patient was referred to our hospital for bilateral facial paralysis. 21 days prior to admission he had developed high fever, chills, headache, fatigue, general malaise, nausea and vomiting. Neurological examination revealed bilateral ptosis of lower lip and cheeks, as well as failure of bilateral eyes closure. Analysis of cerebrospinal fluid (CSF) revealed pleocytosis, a marked rise of micro total protein and a marked rise of intrathecal lgG synthesis. The result of HIV-1 serology was positive by ELISA and that was confirmed by western blot. His CD4 + cell count was 180 cells/mm 3. HIV-1 viral load in CSF was almost 10 times higher than that in plasma. The patient’s condition improved steadily and experienced complete resolution of bilateral PFP after 2 months.

Key words: human immunodeficiency virus, acquired immune deficiency syndrome, acute human immunodeficiency virus-1 infection, peripheral facial paralysis

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