Chinese Medical Sciences Journal ›› 2019, Vol. 34 ›› Issue (3): 205-210.doi: 10.24920/003490
• Original Article • Previous Articles Next Articles
Cui Junpeng1, Lin Meiyi2, Liu Zhenghao3, Liu Baolin1, *()
Received:
2018-12-20
Published:
2019-09-30
Contact:
Liu Baolin
E-mail:liubl@sj-hospital.org
Cui Junpeng, Lin Meiyi, Liu Zhenghao, Liu Baolin. Association between GSTT1 Homozygous Deletion and Risk of Pancreatic Cancer: A Meta Analysis[J].Chinese Medical Sciences Journal, 2019, 34(3): 205-210.
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Table 1
Baseline characteristics of the studies included in the literature"
Study | Year of publication | Ethnics | Country | Genotyping methods | Control group (number of cases) | Case group (number of cases) | |||
---|---|---|---|---|---|---|---|---|---|
Null GSTT1 | Present GSTT1 | Null GSTT1 | Present GSTT1 | ||||||
Liu et al16 | 2000 | Caucasian | Canada | PCR | 26 | 99 | 30 | 119 | |
Duell et al15 | 2002 | Caucasian | America | Multiplex PCR | 149 | 704 | 46 | 214 | |
Duell et al15 | 2002 | African | America | Multiplex PCR | 8 | 28 | 5 | 21 | |
Duell et al15 | 2002 | Asian | America | Multiplex PCR | 21 | 31 | 9 | 8 | |
Cheng et al17 | 2003 | Asian | China | PCR | 174 | 162 | 160 | 156 | |
Jiao et al18 | 2007 | Caucasian | America | Multiplex PCR | 67 | 248 | 74 | 271 | |
Guo et al19 | 2008 | Asian | China | Multiplex PCR | 269 | 316 | 164 | 174 | |
Vrana et al9 | 2009 | Caucasian | Czech | Real-time PCR | 39 | 308 | 45 | 199 | |
Zhang et al20 | 2010 | Asian | China | Multiplex PCR | 67 | 83 | 104 | 46 | |
Jiang et al21 | 2011 | Asian | China | Duplex PCR | 180 | 186 | 120 | 62 | |
Yamada et al22 | 2014 | Asian | Japan | Real-time PCR | 191 | 209 | 167 | 193 |
Table 2
Quality assessment of the included studies using Newcastle-Ottawa scale"
Items | Liu et al16 | Duell et al15 | Cheng et al17 | Jiao et al18 | Guo et al19 | Vrana et al9 | Zhang et al20 | Jiang et al21 | Yamada et al22 |
---|---|---|---|---|---|---|---|---|---|
Selection | |||||||||
Is the case definition adequate? | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
Representativeness of the exposed cohort | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 1 |
Selection of the Controls | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 1 |
Definition of the Controls | 1 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 |
Comparability | |||||||||
The study controls the most important confounding factors | 0 | 1 | 1 | 0 | 1 | 0 | 1 | 1 | 1 |
The study controls other important confounding factors | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 1 |
Exposure | |||||||||
Ascertainment of exposure | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
Same method of ascertainment for the Cases and Controls | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
Non-response rate | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
Total score | 8 | 9 | 6 | 8 | 6 | 7 | 6 | 6 | 8 |
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