Chinese Medical Sciences Journal ›› 2020, Vol. 35 ›› Issue (1): 95-100.doi: 10.24920/003574

• Case Report • Previous Articles     Next Articles

Acute Pancreatitis Complicated by Sheehan's Syndrome: A Case Report and Literature Review

Liu Dasheng1, Liu Li2, Gan Feng3, Wu Xianlin4, Ye Gang5, *()   

  1. 1Department of Vascular and Thyroid Surgery, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou 510120, China
    2Outpatient Department, Guangzhou 510632, China
    3School of Chemistry and Chemical Engineering, Sun Yat-Sen University, Guangzhou 510275, China
    4Center for Diagnosis and Treatment of Pancreatic Disease, Guangzhou 510632, China
    5Department of Gastroenterology, The First Affiliated Hospital of Jinan University, Guangzhou 510632, China
  • Received:2019-05-18 Online:2020-03-31 Published:2020-02-29
  • Contact: Ye Gang E-mail:dr.yegang@qq.com
  • Supported by:
    This study was supported by the Fundamental Research Funds for the Central Universities(21614306);National Natural Science Foundation of China(81403302);Administration of Traditional Chinese Medicine of Guangdong Province, China(20131152);Medical Scientific Research Foundation of Guangdong Province, China(2011336)
The authors successfully treated a case of Sheehan's syndrome accompanied by acute pancreatitis. Patients with this disease usually manifest symptoms of severe acute pancreatitis even when no pancreatic necrosis appears or necrosis is slight on CT scan. Therefore, for women with high triglycerides type acute pancreatitis, primary hypothyroidism or secondary hypothyroidism induced by Sheehan's syndrome should be excluded first.

Abstract:

A 44-year-old woman was transferred to the ICU of the First Affiliated Hospital of Jinan University for 2 days of persistent epigastric pain and 7 hours of unconsciousness. Her admission diagnosis was severe acute necrotizing pancreatitis (hypertriglyceridemia type) with multiple organ dysfunctions. The results of CT revealed a small area of necrotizing pancreatitis, which was not consistent with the severe clinical manifestations. Considering lack of hair and history of postpartum hemorrhage, hormone examination was carried out. According to the results of the examination, she was further diagnosed as Sheehan’s syndrome and pituitary crisis. After hormone replacement therapy, her condition improved rapidly.

Key words: acute pancreatitis, Sheehan's syndrome, pituitary crisis, hypertriglyceridemia

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