Chinese Medical Sciences Journal ›› 2011, Vol. 26 ›› Issue (4): 231-236.doi: 10.1016/S1001-9294(12)60006-6

• Original Article • Previous Articles     Next Articles

Diagnosis and Treatment of Uveal Effusion Syndrome: a Case Series and Literature Review

Chan Wu, Fang-tian Dong*, Hua Zhang, You-xin Chen, Rong-ping Dai, and Ke Tan   

  1. Department of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China
  • Received:2011-07-13 Online:2011-12-30 Published:2011-12-30
  • Contact: Corresponding author Tel: 86-10-65296362, Fax: 86-10-65296351, E-mail:

Abstract: Objective To explore the diagnosis, classification, and management of uveal effusion syndrome (UES).
Methods The clinical data of 10 patients diagnosed with UES in our hospital between 1990-2010 were extracted from hospital records and analyzed, including ophthalmologic examination, ophthalmologic ultrasonography, ultrasound biomicroscopy (UBM), fundus fluorescence angiography (FFA), indocyanine green (ICG) angiography, surgical procedures, and outcomes.
Results The fundus examination of all impacted eyes showed bullous retinal detachment shifting with head position, confirmed by ultrasonography revealing retinal and choroidal detachment. UBM showed annular peripheral ciliochoroidal detachment in all cases. FFA was performed in 5 patients and revealed leopard spots without leakage from choroid into subretinal space. ICG angiograpy was performed in 3 patients and demonstrated diffused granular marked hyperfluorescence in the choroidal fluorescence in the very early phase, which increased with time and persisted until the late phase. Four eyes of 2 patients underwent full-thickness sclerectomies and 1 eye of 1 patient underwent subscleral sclerectomy, all of whom achieved reattachment of the retina without recurrence during 1-year follow-up.
Conclusions Comprehensive preoperative evaluation, including ophthalmologic ultrasonography, computed tomography, and magnetic resonance imaging, is crucial for accurate classification of UES and selection of proper management strategy. Surgical treatment can achieve optimal clinical outcomes for type 1 and type 2 UES.

Key words: uveal effusion syndrome, idiopathic, classification, sclerectomy

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