%A You-xin Ji*, Ke-tao Lan, Chuan-xin Geng, Xiao Zou, and Song-ping Wang %T Modified Approach for Establishing Filament-induced Permanent Middle Cerebral Artery Occlusion Rats and Mice Models %0 Journal Article %D 2011 %J Chinese Medical Sciences Journal %R 10.1016/S1001-9294(12)60013-3 %P 257-258 %V 26 %N 4 %U {http://cmsj.cams.cn/CN/abstract/article_98.shtml} %8 2011-12-30 %X BRAIN ischemia stroke is a devastating disease, with more than 10% stroke patients either severely disabled or dead. Although rodent fil- ament middle cerebral artery occlusion (MCAO) model can mimic human brain ischemic stroke well, its wide use was restricted by difficulty in surgery, especially in ligating pterygopalatine artery (PPA).