延髓发病型及脊髓发病型肌萎缩侧索硬化症脑部磁共振结构特征变化

陈志晔,刘梦琦,马林

Gray Matter Volume Changes over the Whole Brain in the Bulbar- and Spinal-onset Amyotrophic Lateral Sclerosis: a Voxel-based Morphometry Study

Chen Zhiye,Liu Mengqi,Ma Lin

Table 2 Volume comparisons of the brain regions with decreased GMV and TGMV, TIV, fGMV between the ALS-bulbar and NC groups (10-3 ml)

Groups n Volume of lMedOrbGy Volume of lInfTemGy Volume of rMidTemGy means±SD 95% CI means±SD 95% CI means±SD 95% CI NCs 65 4.40±0.57 4.08-4.64 10.00±1.00 9.39-10.59 14.14±1.97 13.09-14.76 bulbar-onset ALS 15 4.15±0.51 3.91-4.47 8.94±1.17 8.35-9.55 13.49±1.46 12.87-14.54 F value 0.70 6.19 0.14 P value* 0.41 0.02 0.71 Groups n TGMV TIV fGMV means±SD 95% CI means±SD 95% CI means±SD 95% CI NCs 65 610.75±56.74 589.83-617.29 1423.72±127.38 1385.11-1453.02 0.43±0.02 0.42-0.43 bulbar-onset ALS 15 577.18±65.12 554.32-614.58 1366.53±133.84 1309.04-1441.14 0.42±0.02 0.41-0.44 F value 0.07 0 0.32 P value* 0.80 0.98 0.58