延髓发病型及脊髓发病型肌萎缩侧索硬化症脑部磁共振结构特征变化

陈志晔,刘梦琦,马林

Gray Matter Volume Changes over the Whole Brain in the Bulbar- and Spinal-onset Amyotrophic Lateral Sclerosis: a Voxel-based Morphometry Study

Chen Zhiye,Liu Mengqi,Ma Lin

Table 3 Brain regions with decreased GM volume in patients with ALS-spinal compared with NCs

Anatomic region	MNI-space			K value	P value	T value
Anatomic region	X	Y	Z	K value	P value	T value
Left Thalamus Proper	-21	-21	12	928	0.000	5.58
Right Precentral Gyrus	48	-9	57	2753	0.000	5.46
Left Superior Frontal Gyrus	-18	54	6	4582	0.000	5.35
Left Postcentral Gyrus	-54	-8	33	4032	0.000	5.15
Right Middle Frontal Gyrus	42	53	9	1015	0.000	4.88
Left Central Operculum	-54	2	3	633	0.000	4.27
Right Superior Frontal Gyrus	23	54	21	351	0.000	4.24
Right Middle Occipital Gyrus	32	-75	41	215	0.000	4.15
Left Supramarginal Gyrus	-45	-48	24	141	0.000	4.14
Left Precuneus	-5	-65	27	1157	0.000	4.06
Left Middle Occipital Gyrus	-29	-80	15	293	0.000	4.00
Left Medial Precentral Gyrus	0	-18	75	220	0.000	3.97
Right Superior Frontal Gyrus	26	33	47	123	0.000	3.96
Right Middle Temporal Gyrus	60	-20	-8	274	0.000	3.95
Right Angular Gyrus	57	-48	18	166	0.000	3.87
Left Angular Gyrus	-48	-60	35	153	0.000	3.78
Left Inferior Frontal Angular Gyrus	-48	26	6	130	0.000	3.74
Left Fusiform Gyrus	-32	-33	-29	177	0.000	3.70
Left Superior Frontal Gyrus	-17	39	48	300	0.000	3.69
Left Superior Parietal Lobule	-26	-54	56	176	0.000	3.67