延髓发病型及脊髓发病型肌萎缩侧索硬化症患者皮层变薄模态:基于表面的形态学研究
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陈志晔,刘梦琦,马林
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Cortical Thinning Pattern of Bulbar- and Spinal-onset Amyotrophic Lateral Sclerosis: a Surface-based Morphometry Study
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Chen Zhiye,Liu Mengqi,Ma Lin
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Table 2 Brain regions with cortical thinning in ALS compared with controls |
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Cluster | Anatomic region | MNI-space | K value | Pvalue | tvalue | X | Y | Z | ALS vs. NC | | | | | | | 1 | Left precentral gyrus | -9 | -24 | 76 | 619 | 0.000 | 4.15 | 2 | Left postcentral gyrus | -56 | -9 | 19 | 293 | 0.000 | 3.70 | 3 | Right gyrus rectus | 4 | 43 | -22 | 150 | 0.000 | 3.41 | 4 | Right medial precentral gyrus | 6 | -22 | 73 | 191 | 0.000 | 3.37 | ALS-bulbar vs. NC | | | | | | | 5 | Left precentral gyrus | -25 | -16 | 68 | 154 | 0.000 | 4.20 | 6 | Righ SMC | 8 | -8 | 69 | 219 | 0.000 | 4.45 | ALS-spinal vs. NC | | | | | | | 7 | Left posterior insula | -36 | -13 | -5 | 264 | 0.000 | 3.85 | 8 | Right gyrus rectus | 5 | 42 | -24 | 210 | 0.000 | 3.51 |
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