延髓发病型及脊髓发病型肌萎缩侧索硬化症患者皮层变薄模态：基于表面的形态学研究

陈志晔,刘梦琦,马林

Cortical Thinning Pattern of Bulbar- and Spinal-onset Amyotrophic Lateral Sclerosis: a Surface-based Morphometry Study

Chen Zhiye,Liu Mengqi,Ma Lin

Table 3 The correlation analysis between the cortical thickness of thinning brain regions and clinical variables in ALS^§

Brain regions	Cortical thickness (mm)	Disease duration		ALSFRS-R score
Brain regions	Cortical thickness (mm)	r	Pvalue	r	Pvalue
ALS vs. NC
Left precentral gyrus	2.77±0.22	0.003	0.979	0.245	0.053
Left postcentral gyrus	2.26±0.19	-0.052	0.684	0.126	0.326
Right gyrus rectus	3.31±0.19	-0.311	0.013	-0.018	0.886
Right precentral gyrus	2.88±0.15	-0.081	0.528	0.271	0.032
ALS-spinal vs. NC
Left insula	3.95±0.35	-0.409	0.004	-0.011	0.943
Right gyrus rectus	3.34±0.19	-0.351	0.014	-0.022	0.881
ALS-bulbar vs. NC
Left precentral gyrus	2.70±0.22	-0.226	0.458	0.224	0.461
Right supplementary motor cortex	2.19±0.14	0.071	0.818	0.204	0.505