Application of SYNTAX and its Derivative Scores in the Selection of Revascularization Strategies for Complex Coronary Heart Disease

Yuxu Zhang; Rongruo Zeng; Ye Yang; Yin Shen

doi:10.24920/004085

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Application of SYNTAX and its Derivative Scores in the Selection of Revascularization Strategies for Complex Coronary Heart Disease

Chinese Medical Sciences Journal Vol. 37, Issue 4, Pages: 340-348(2022)

Review | Updated：2024-04-10

- Application of SYNTAX and its Derivative Scores in the Selection of Revascularization Strategies for Complex Coronary Heart Disease
- Affiliations：
  
  1. 1Department of International Medical Services, People’s Hospital of Guangxi Zhuang Autonomous Region, Nanning 530021, China
  2. 2School of Graduate, Guangxi Medical University, Nanning 530021, China
- Author bio：
  
  * 86-18978918347, E-mail: sy_doctor@163.com
- Funds：
- DOI：10.24920/004085
  CLC：
- Received：18 March 2022，
  
  Accepted：2022-8-2，
  
  Published Online：23 September 2022，
  
  Published：31 December 2022
- Accepted：
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Yuxu Zhang, Rongruo Zeng, Ye Yang, et al. Application of SYNTAX and its Derivative Scores in the Selection of Revascularization Strategies for Complex Coronary Heart Disease[J]. Chinese medical sciences journal, 2022, 37(4): 340-348.
DOI：

Yuxu Zhang, Rongruo Zeng, Ye Yang, et al. Application of SYNTAX and its Derivative Scores in the Selection of Revascularization Strategies for Complex Coronary Heart Disease[J]. Chinese medical sciences journal, 2022, 37(4): 340-348. DOI： 10.24920/004085.

摘要

复杂冠心病因其冠状动脉解剖结构复杂、临床因素多变、血运重建难度大、药物保守治疗效果有限等特点，近年来成为医学研究领域的热点。而随着血运重建技术的日臻完善和冠状动脉危险分层评分的引入，使得复杂冠心病的识别和最佳治疗方式的选择更加科学化。作为一种新兴的冠状动脉危险分层评分工具，SYNTAX及其衍生评分基于冠状动脉血管病变的复杂性及严重性，定量描述冠状动脉的病变特点，以辅助临床医师合理选择冠状动脉血运重建治疗的策略。本文总结了SYNTAX及其衍生评分在复杂冠心病中的应用情况，期望能加深临床医师对复杂冠心病不同血运重建策略抉择的认识，为复杂冠心病的救治提供参考。

Abstract

Complex coronary heart disease (CHD) has become a hot spot in medicine due to its complex coronary anatomy

variable clinical factors

difficult hemodynamic reconstruction

and limited effect of conservative drug treatment. Identifying complex CHD and selecting optimal treatment methods have become more scientific as revascularization technology has improved

and coronary risk stratification scores have been introduced. SYNTAX and its derivative scores are decision-making tools that quantitatively describe the characteristics of coronary lesions in patients based on their complexity and severity. The SYNTAX and its derivative scores could assist clinicians in rationalizing the selection of hemodynamic reconstruction treatment strategies

and have demon-strated outstanding value in evaluating the prognosis of patients with complex CHD undergoing revascularization treatment. The authors in this article summary the practical application of SYNTAX and its derivative scores in complex CHD in order to deepen the understanding of the relationship between the choice of different revascularization strategies and SYNTAX and its derived scores in complex CHD and provide a further reference for clinical treatment of complex CHD.

关键词

Keywords

references

Roth GA , Huffman MD , Moran AE , et al . Global and regional patterns in cardiovascular mortality from 1990 to 2013 . Circulation 2015 ; 132 ( 17 ): 1667 - 78 . doi: 10.1161/circulationaha.114.008720 https://dx.doi.org/10.1161/circulationaha.114.008720 . DOI: 10.1161/CIRCULATIONAHA.114.008720 http://doi.org/10.1161/CIRCULATIONAHA.114.008720

Sousa-Uva M , Neumann FJ , Ahlsson A , et al . 2018 ESC/EACTS guidelines on myocardial revascularization . Eur J Cardiothorac Surg 2019 ; 55 ( 1 ): 4 - 90 . doi: 10.1093/ejcts/ezy289 https://dx.doi.org/10.1093/ejcts/ezy289 . DOI: 10.1093/ejcts/ezy289 http://doi.org/10.1093/ejcts/ezy289 https://academic.oup.com/ejcts/article/55/1/4/5079878 https://academic.oup.com/ejcts/article/55/1/4/5079878

Hang YL . Guidelines for percutaneous coronary intervention in China (2016) . Chin J Cardiol 2016 ; 44 ( 5 ): 382 - 400 .

Ong AT , Serruys PW , Mohr FW , et al . The SYNergy between percutaneous coronary intervention with TAXus and cardiac surgery (SYNTAX) study: design, rationale, and run-in phase . Am Heart J 2006 ; 151 ( 6 ): 1194 - 204 . doi: 10.1016/j.ahj.2005.07.017 https://dx.doi.org/10.1016/j.ahj.2005.07.017 . DOI: 10.1016/j.ahj.2005.07.017 http://doi.org/10.1016/j.ahj.2005.07.017

Serruys PW , Morice MC , Kappetein AP , et al . Percutaneous coronary intervention versus coronary-artery bypass grafting for severe coronary artery disease . N Engl J Med 2009 ; 360 ( 10 ): 961 - 72 . doi: 10.1056/NEJMoa0804626 https://dx.doi.org/10.1056/NEJMoa0804626 . DOI: 10.1056/NEJMoa0804626 http://doi.org/10.1056/NEJMoa0804626 http://www.nejm.org/doi/abs/10.1056/NEJMoa0804626 http://www.nejm.org/doi/abs/10.1056/NEJMoa0804626

Mohr FW , Morice MC , Kappetein AP , et al . Coronary artery bypass graft surgery versus percutaneous coronary intervention in patients with three-vessel disease and left main coronary disease: 5-year follow-up of the randomised, clinical SYNTAX trial . Lancet 2013 ; 381 ( 9867 ): 629 - 38 . doi: 10.1016/s0140-6736(13)60141-5 https://dx.doi.org/10.1016/s0140-6736(13)60141-5 . DOI: 10.1016/s0140-6736(13)60141-5 http://doi.org/10.1016/s0140-6736(13)60141-5 https://linkinghub.elsevier.com/retrieve/pii/S0140673613601415 https://linkinghub.elsevier.com/retrieve/pii/S0140673613601415

van Dongen IM , Elias J , García-García HM , et al . Value of the SYNTAX score in ST-elevation myocardial infarction patients with a concomitant chronic total coronary occlusion (from the EXPLORE Trial) . Am J Cardiol 2019 ; 123 ( 7 ): 1035 - 43 . doi: 10.1016/j.amjcard.2018.12.028 https://dx.doi.org/10.1016/j.amjcard.2018.12.028 . DOI: S0002-9149(19)30031-1 http://doi.org/S0002-9149(19)30031-1

Shlofmitz E , Généreux P , Chen S , et al . Left main coronary artery disease revascularization according to the SYNTAX score . Circ Cardiovasc Interv 2019 ; 12 ( 9 ): e008 007. doi: 10.1161/circinterventions.118.008007 https://dx.doi.org/10.1161/circinterventions.118.008007 . DOI: 10.1161/circinterventions.118.008007 http://doi.org/10.1161/circinterventions.118.008007

Thuijs D , Kappetein AP , Serruys PW , et al . Percutaneous coronary intervention versus coronary artery bypass grafting in patients with three-vessel or left main coronary artery disease: 10-year follow-up of the multicentre randomised controlled SYNTAX trial . Lancet 2019 ; 394 ( 10206 ): 1325 - 34 . doi: 10.1016/s0140-6736(19)31997-x https://dx.doi.org/10.1016/s0140-6736(19)31997-x . DOI: 10.1016/s0140-6736(19)31997-x http://doi.org/10.1016/s0140-6736(19)31997-x https://linkinghub.elsevier.com/retrieve/pii/S014067361931997X https://linkinghub.elsevier.com/retrieve/pii/S014067361931997X

Park DW , Kim YH , Yun SC , et al . Complexity of atherosclerotic coronary artery disease and long-term outcomes in patients with unprotected left main disease treated with drug-eluting stents or coronary artery bypass grafting . J Am Coll Cardiol 2011 ; 57 ( 21 ): 2152 - 9 . doi: 10.1016/j.jacc.2011.01.033 https://dx.doi.org/10.1016/j.jacc.2011.01.033 . DOI: 10.1016/j.jacc.2011.01.033 http://doi.org/10.1016/j.jacc.2011.01.033 https://linkinghub.elsevier.com/retrieve/pii/S073510971101179X https://linkinghub.elsevier.com/retrieve/pii/S073510971101179X

Magro M , Nauta S , Simsek C , et al . Value of the SYNTAX score in patients treated by primary percutaneous coronary intervention for acute ST-elevation myocardial infarction: the MI SYNTAX score study . Am Heart J 2011 ; 161 ( 4 ): 771 - 81 . doi: 10.1016/j.ahj.2011.01.004 https://dx.doi.org/10.1016/j.ahj.2011.01.004 . DOI: 10.1016/j.ahj.2011.01.004 http://doi.org/10.1016/j.ahj.2011.01.004 https://linkinghub.elsevier.com/retrieve/pii/S0002870311000147 https://linkinghub.elsevier.com/retrieve/pii/S0002870311000147

Palmerini T , Genereux P , Caixeta A , et al . Prognostic value of the SYNTAX score in patients with acute coronary syndromes undergoing percutaneous coronary intervention: analysis from the ACUITY (Acute Catheterization and Urgent Intervention Triage Strategy) trial . J Am Coll Cardiol 2011 ; 57 ( 24 ): 2389 - 97 . doi: 10.1016/j.jacc.2011.02.032 https://dx.doi.org/10.1016/j.jacc.2011.02.032 . DOI: 10.1016/j.jacc.2011.02.032 http://doi.org/10.1016/j.jacc.2011.02.032

Sabatine MS , Bergmark BA , Murphy SA , et al . Percutaneous coronary intervention with drug-eluting stents versus coronary artery bypass grafting in left main coronary artery disease: an individual patient data meta-analysis . Lancet 2021 ; 398 ( 10318 ): 2247 - 57 . doi: 10.1016/s0140-6736(21)02334-5 https://dx.doi.org/10.1016/s0140-6736(21)02334-5 . DOI: 10.1016/S0140-6736(21)02334-5 http://doi.org/10.1016/S0140-6736(21)02334-5

Yoon YH , Ahn JM , Kang DY , et al . Impact of SYNTAX score on 10-year outcomes after revascularization for left main coronary artery disease . JACC Cardiovasc Interv 2020 ; 13 ( 3 ): 361 - 71 . doi: 10.1016/j.jcin.2019.10.020 https://dx.doi.org/10.1016/j.jcin.2019.10.020 . DOI: 10.1016/j.jcin.2019.10.020 http://doi.org/10.1016/j.jcin.2019.10.020 https://linkinghub.elsevier.com/retrieve/pii/S1936879819321715 https://linkinghub.elsevier.com/retrieve/pii/S1936879819321715

Lee J , Ahn JM , Kim JH , et al . Prognostic effect of the SYNTAX score on 10-year outcomes after left main coronary artery revascularization in a randomized population: insights from the extended PRECOMBAT trial . J Am Heart Assoc 2021 ; 10 ( 14 ): e020359 . doi: 10.1161/jaha. 120.020359 https://dx.doi.org/10.1161/jaha. 120.020359 . DOI: 10.1161/jaha. 120.020359 http://doi.org/10.1161/jaha. 120.020359 https://www.ahajournals.org/doi/10.1161/JAHA.120.020359 https://www.ahajournals.org/doi/10.1161/JAHA.120.020359

Garg S , Sarno G , Garcia-Garcia HM , et al . A new tool for the risk stratification of patients with complex coronary artery disease: the Clinical SYNTAX Score . Circ Cardiovasc Interv 2010 ; 3 ( 4 ): 317 - 26 . doi: 10.1161/circinterventions.109.914051 https://dx.doi.org/10.1161/circinterventions.109.914051 . DOI: 10.1161/CIRCINTERVENTIONS.109.914051 http://doi.org/10.1161/CIRCINTERVENTIONS.109.914051

Gao G , Zhang D , Song C , et al . Integrating the residual SYNTAX score to improve the predictive ability of the age, creatinine, and ejection fraction (ACEF) score for cardiac mortality in percutaneous coronary intervention patients . Catheter Cardiovasc Interv 2020 ; 95 Suppl 1 : 534 - 41 . doi: 10.1002/ccd.28673 https://dx.doi.org/10.1002/ccd.28673 . DOI: 10.1002/ccd.28673 http://doi.org/10.1002/ccd.28673 https://onlinelibrary.wiley.com/toc/1522726x/95/S1 https://onlinelibrary.wiley.com/toc/1522726x/95/S1

Janella BL , Campos CM , Caixeta A , et al . Assessment of long-term mortality in patients with complex coronary artery disease undergoing percutaneous intervention: comparison of multiple anatomical and clinical prognostic risk scores . EuroIntervention 2017 ; 13 ( 10 ): 1177 - 84 . doi: 10.4244/eij-d-16-00659 https://dx.doi.org/10.4244/eij-d-16-00659 . DOI: EIJ-D-16-00659 http://doi.org/EIJ-D-16-00659

Li XQ , Yin C , Li XL , et al . Comparison of the prognostic value of SYNTAX score and clinical SYNTAX score on outcomes of Chinese patients underwent percutaneous coronary intervention . BMC Cardiovasc Disord 2021 ; 21 ( 1 ): 334 . doi: 10.1186/s12872-021-02144-w https://dx.doi.org/10.1186/s12872-021-02144-w . DOI: 10.1186/s12872-021-02144-w http://doi.org/10.1186/s12872-021-02144-w https://doi.org/10.1186/s12872-021-02144-w https://doi.org/10.1186/s12872-021-02144-w

Onuk T , Güngör B , İpek G , et al . Comparison of long-term prognostic value of baseline SYNTAX and clinical SYNTAX scores in ST-segment elevation myocardial infarction patients with multivessel disease . Coron Artery Dis 2016 ; 27 ( 4 ): 311 - 8 . doi: 10.1097/mca.0000000000000365 https://dx.doi.org/10.1097/mca.0000000000000365 . DOI: 10.1097/mca.0000000000000365 http://doi.org/10.1097/mca.0000000000000365 https://journals.lww.com/00019501-201606000-00010 https://journals.lww.com/00019501-201606000-00010

Kawashima H , Hara H , Wang R , et al . Usefulness of updated logistic clinical SYNTAX score based on MI-SYNTAX score in patients with ST-elevation myocardial infarction . Catheter Cardiovasc Interv 2021 ; 97 ( 7 ): E919 -e28. doi: 10.1002/ccd.29383 https://dx.doi.org/10.1002/ccd.29383 . DOI: 10.1002/ccd.29383 http://doi.org/10.1002/ccd.29383

Song Y , Gao Z , Tang XF , et al . Impact of residual SYNTAX score and its derived indexes on clinical outcomes after percutaneous coronary intervention: data from a large single center . Chin Med J (Engl) 2018 ; 131 ( 12 ): 1390 - 6 . doi: 10.4103/0366-6999.233958 https://dx.doi.org/10.4103/0366-6999.233958 . DOI: 10.4103/0366-6999.233958 http://doi.org/10.4103/0366-6999.233958

Collet C , Onuma Y , Miyazaki Y , et al . Integration of non-invasive functional assessments with anatomical risk stratification in complex coronary artery disease: the non-invasive functional SYNTAX score . Cardiovasc Diagn Ther 2017 ; 7 ( 2 ): 151 - 8 . doi: 10.21037/cdt.2017.03.19 https://dx.doi.org/10.21037/cdt.2017.03.19 . DOI: 10.21037/cdt.2017.03.19 http://doi.org/10.21037/cdt.2017.03.19 http://cdt.amegroups.com/ http://cdt.amegroups.com/

Kundu A , Sardar P , O’Day K , et al . SYNTAX score and outcomes of coronary revascularization in diabetic patients . Curr Cardiol Rep 2018 ; 20 ( 5 ): 28 . doi: 10.1007/s11886-018-0971-1 https://dx.doi.org/10.1007/s11886-018-0971-1 . DOI: 10.1007/s11886-018-0971-1 http://doi.org/10.1007/s11886-018-0971-1

He J , Zhao H , Yu X , et al . SYNTAX score-Ⅱ predicts long-term mortality in patients who underwent left main percutaneous coronary intervention treated with second-generation drug-eluting stents . Int Heart J 2017 ; 58 ( 3 ): 344 - 50 . doi: 10.1536/ihj.16-292 https://dx.doi.org/10.1536/ihj.16-292 . DOI: 10.1536/ihj.16-292 http://doi.org/10.1536/ihj.16-292 https://www.jstage.jst.go.jp/article/ihj/58/3/58_16-292/_article https://www.jstage.jst.go.jp/article/ihj/58/3/58_16-292/_article

Xu B , Généreux P , Yang Y , et al . Validation and comparison of the long-term prognostic capability of the SYNTAX score-Ⅱ among 1,528 consecutive patients who underwent left main percutaneous coronary intervention . JACC Cardiovasc Interv 2014 ; 7 ( 10 ): 1128 - 37 . doi: 10.1016/j.jcin.2014.05.018 https://dx.doi.org/10.1016/j.jcin.2014.05.018 . DOI: 10.1016/j.jcin.2014.05.018 http://doi.org/10.1016/j.jcin.2014.05.018 https://linkinghub.elsevier.com/retrieve/pii/S1936879814011716 https://linkinghub.elsevier.com/retrieve/pii/S1936879814011716

Salvatore A , Boukhris M , Giubilato S , et al . Usefulness of SYNTAX score Ⅱ in complex percutaneous coronary interventions in the setting of acute coronary syndrome . J Saudi Heart Assoc 2016 ; 28 ( 2 ): 63 - 72 . doi: 10.1016/j.jsha.2015.07.003 https://dx.doi.org/10.1016/j.jsha.2015.07.003 . DOI: 10.1016/j.jsha.2015.07.003 http://doi.org/10.1016/j.jsha.2015.07.003 https://linkinghub.elsevier.com/retrieve/pii/S1016731515001608 https://linkinghub.elsevier.com/retrieve/pii/S1016731515001608

Campos CM , van Klaveren D , Farooq V , et al . Long-term forecasting and comparison of mortality in the evaluation of the Xience Everolimus eluting stent vs . coronary artery bypass surgery for effectiveness of left main revascularization (EXCEL) trial: prospective validation of the SYNTAX score Ⅱ . Eur Heart J 2015 ; 36 ( 20 ): 1231 - 41 . doi: 10.1093/eurheartj/ehu518 https://dx.doi.org/10.1093/eurheartj/ehu518 . DOI: 10.1093/eurheartj/ehu518 http://doi.org/10.1093/eurheartj/ehu518 https://academic.oup.com/eurheartj/article-lookup/doi/10.1093/eurheartj/ehu518 https://academic.oup.com/eurheartj/article-lookup/doi/10.1093/eurheartj/ehu518

Hara H , Shiomi H , van Klaveren D , et al . External validation of the SYNTAX score Ⅱ 2020 . J Am Coll Cardiol 2021 ; 78 ( 12 ): 1227 - 38 . doi: 10.1016/j.jacc.2021.07.027 https://dx.doi.org/10.1016/j.jacc.2021.07.027 . DOI: 10.1016/j.jacc.2021.07.027 http://doi.org/10.1016/j.jacc.2021.07.027 https://linkinghub.elsevier.com/retrieve/pii/S0735109721057077 https://linkinghub.elsevier.com/retrieve/pii/S0735109721057077

He JQ , Yu XP , Peng C , et al . Predictive ability of the SYNergy between percutaneous coronary intervention with TAXus and cardiac surgery score Ⅱ for long-term mortality in patients with three-vessel coronary artery disease undergoing percutaneous coronary intervention treated with second-generation drug-eluting stents . Chin Med J (Engl) 2015 ; 128 ( 16 ): 2176 - 82 . doi: 10.4103/0366-6999.162510 https://dx.doi.org/10.4103/0366-6999.162510 . DOI: 10.4103/0366-6999.162510 http://doi.org/10.4103/0366-6999.162510

Takahashi K , Serruys PW , Fuster V , et al . Redevelopment and validation of the SYNTAX score Ⅱ to individualise decision making between percutaneous and surgical revascularisation in patients with complex coronary artery disease: secondary analysis of the multicentre randomised controlled SYNTAXES trial with external cohort validation . Lancet 2020 ; 396 ( 10260 ): 1399 - 412 . doi: 10.1016/s0140-6736(20)32114-0 https://dx.doi.org/10.1016/s0140-6736(20)32114-0 . DOI: 10.1016/S0140-6736(20)32114-0 http://doi.org/10.1016/S0140-6736(20)32114-0

Yang H , Zhang L and Xu CH . Use of the SYNTAX score Ⅱ to predict mortality in interventional cardiology: a systematic review and meta-analysis . Medicine (Baltimore) 2019 ; 98 ( 2 ): e140 43. doi: 10.1097/md.0000000000014043 https://dx.doi.org/10.1097/md.0000000000014043 . DOI: 10.1097/md.0000000000014043 http://doi.org/10.1097/md.0000000000014043

Yesin M , Çağdaş M , Kalçık M , et al . Comparison of syntax score and syntax score Ⅱ to predict “no reflow phenomenon” in patients with ST-segment elevation myocardial infarction . Int J Cardiovasc Imaging 2017 ; 33 ( 12 ): 1883 - 9 . doi: 10.1007/s10554-017-1200-5 https://dx.doi.org/10.1007/s10554-017-1200-5 . DOI: 10.1007/s10554-017-1200-5 http://doi.org/10.1007/s10554-017-1200-5 http://link.springer.com/10.1007/s10554-017-1200-5 http://link.springer.com/10.1007/s10554-017-1200-5

Campos CM , van Klaveren D , Iqbal J , et al . Predictive performance of SYNTAX score Ⅱ in patients with left main and multivessel coronary artery disease-analysis of CREDO-Kyoto registry . Circ J 2014 ; 78 ( 8 ): 1942 - 9 . doi: 10.1253/circj.cj-14-0204 https://dx.doi.org/10.1253/circj.cj-14-0204 . DOI: 10.1253/circj.cj-14-0204 http://doi.org/10.1253/circj.cj-14-0204 https://www.jstage.jst.go.jp/article/circj/78/8/78_CJ-14-0204/_article https://www.jstage.jst.go.jp/article/circj/78/8/78_CJ-14-0204/_article

Chen H , Li JX , Wang H , et al . Correlation between SYNTAX score of coronary heart disease and ultrasound-guided cerebral infarction typing in patients with coronary artery diseases . Chin Circ J 2021 ; 36 ( 2 ): 144 - 8 .

Obeid S , Attinger-Toller A , Taramasso M , et al . SYNTAX score Ⅱ in patients with coronary artery disease undergoing percutaneous mitral repair with the MitraClip . Int J Cardiol 2017 ; 236 : 375 - 80 . doi: 10.1016/j.ijcard.2017.02.049 https://dx.doi.org/10.1016/j.ijcard.2017.02.049 . DOI: 10.1016/j.ijcard.2017.02.049 http://doi.org/10.1016/j.ijcard.2017.02.049 https://linkinghub.elsevier.com/retrieve/pii/S0167527316333836 https://linkinghub.elsevier.com/retrieve/pii/S0167527316333836

Bangalore S , Toklu B , Wetterslev J . Complete versus culprit-only revascularization for ST-segment-elevation myocardial infarction and multivessel disease: a meta-analysis and trial sequential analysis of randomized trials . Circ Cardiovasc Interv 2015 ; 8 ( 4 ): 10 . doi: 10.1161/circinterventions.114.002142 https://dx.doi.org/10.1161/circinterventions.114.002142 . DOI: 10.1161/circinterventions.114.002142 http://doi.org/10.1161/circinterventions.114.002142

Lee JM , Rhee TM , Hahn JY , et al . Multivessel percutaneous coronary intervention in patients with ST-segment elevation myocardial infarction with cardiogenic shock . J Am Coll Cardiol 2018 ; 71 ( 8 ): 844 - 56 . doi: 10.1016/j.jacc.2017.12.028 https://dx.doi.org/10.1016/j.jacc.2017.12.028 . DOI: S0735-1097(17)42016-X http://doi.org/S0735-1097(17)42016-X

٣٩ . Wang Y , Zhao X , Zhou P , et al . Culprit-plaque morphology and residual SYNTAX score predict cardiovascular risk in acute myocardial infarction: an optical coherence tomography study . J Atheroscler Thromb 2021 ; 29 ( 9 ): 1328 - 41 . doi: 10.5551/jat.63103 https://dx.doi.org/10.5551/jat.63103 . DOI: 10.5551/jat.63103 http://doi.org/10.5551/jat.63103

Alidoosti M , Saroukhani S , Lotfi-Tokaldany M , et al . Objectifying the level of incomplete revascularization by the residual SYNTAX score and evaluating its impact on the one-year outcome of percutaneous coronary intervention in patients with multi-vessel disease . Cardiovasc Revasc Med 2016 ; 17 ( 5 ): 308 - 12 . doi: 10.1016/j.carrev.2016.03.009 https://dx.doi.org/10.1016/j.carrev.2016.03.009 . DOI: 10.1016/j.carrev.2016.03.009 http://doi.org/10.1016/j.carrev.2016.03.009 https://linkinghub.elsevier.com/retrieve/pii/S155383891630094X https://linkinghub.elsevier.com/retrieve/pii/S155383891630094X

Généreux P , Palmerini T , Caixeta A , et al . Quantification and impact of untreated coronary artery disease after percutaneous coronary intervention: the residual SYNTAX (Synergy between PCI with Taxus and Cardiac Surgery) score . J Am Coll Cardiol 2012 ; 59 ( 24 ): 2165 - 74 . doi: 10.1016/j.jacc.2012.03.010 https://dx.doi.org/10.1016/j.jacc.2012.03.010 . DOI: 10.1016/j.jacc.2012.03.010 http://doi.org/10.1016/j.jacc.2012.03.010

Kochar A , Varshney AS , Wang DE . Residual SYNTAX score after revascularization in cardiogenic shock: when is complete complete ? J Am Coll Cardiol 2021 ; 77 ( 2 ): 156 - 8 . doi: 10.1016/j.jacc.2020.11.034 https://dx.doi.org/10.1016/j.jacc.2020.11.034 . DOI: 10.1016/j.jacc.2020.11.034 http://doi.org/10.1016/j.jacc.2020.11.034

Takahashi K , Serruys PW , Gao C , et al . Ten-year all-cause death according to completeness of revascularization in patients with three-vessel disease or left main coronary artery disease: insights from the SYNTAX extended survival study . Circulation 2021 ; 144 ( 2 ): 96 - 109 . doi: 10.1161/circulationaha.120.046289 https://dx.doi.org/10.1161/circulationaha.120.046289 . DOI: 10.1161/CIRCULATIONAHA.120.046289 http://doi.org/10.1161/CIRCULATIONAHA.120.046289

Lee SH , Choi KH , Lee JM , et al . Residual functional SYNTAX score by quantitative flow ratio and improvement of exercise capacity after revascularization . Catheter Cardiovasc Interv 2021 ; 97 ( 4 ): E454 -e66. doi: 10.1002/ccd.29118 https://dx.doi.org/10.1002/ccd.29118 . DOI: 10.1002/ccd.29118 http://doi.org/10.1002/ccd.29118

Nam CW , Mangiacapra F , Entjes R , et al . Functional SYNTAX score for risk assessment in multivessel coronary artery disease . J Am Coll Cardiol 2011 ; 58 ( 12 ): 1211 - 8 . doi: 10.1016/j.jacc.2011.06.020 https://dx.doi.org/10.1016/j.jacc.2011.06.020 . DOI: 10.1016/j.jacc.2011.06.020 http://doi.org/10.1016/j.jacc.2011.06.020 https://linkinghub.elsevier.com/retrieve/pii/S0735109711023424 https://linkinghub.elsevier.com/retrieve/pii/S0735109711023424

Gong Y , Zheng B , Yi T , et al . Coronary angiography-derived contrast fractional flow reserve . Catheter Cardiovasc Interv 2022 ; 99 ( 3 ): 763 - 71 . doi: 10.1002/ccd.29558 https://dx.doi.org/10.1002/ccd.29558 . DOI: 10.1002/ccd.29558 http://doi.org/10.1002/ccd.29558 https://onlinelibrary.wiley.com/toc/1522726x/99/3 https://onlinelibrary.wiley.com/toc/1522726x/99/3

Li J , Gong Y , Wang W , et al . Accuracy of computational pressure-fluid dynamics applied to coronary angiography to derive fractional flow reserve: FLASH FFR . Cardiovasc Res 2020 ; 116 ( 7 ): 1349 - 56 . doi: 10.1093/cvr/cvz289 https://dx.doi.org/10.1093/cvr/cvz289 . DOI: 10.1093/cvr/cvz289 http://doi.org/10.1093/cvr/cvz289

Pan J , Zhang Q , Lei L , et al . Impact of the caFFR-guided functional SYNTAX score on ventricular tachycardia/fibrillation development in patients with acute myocardial infarction . Front Cardiovasc Med 2022 ; 9 : 807805 . doi: 10.3389/fcvm.2022.807805 https://dx.doi.org/10.3389/fcvm.2022.807805 . DOI: 10.3389/fcvm.2022.807805 http://doi.org/10.3389/fcvm.2022.807805 https://www.frontiersin.org/articles/10.3389/fcvm.2022.807805/full https://www.frontiersin.org/articles/10.3389/fcvm.2022.807805/full

Asano T , Katagiri Y , Chang CC , et al . Angiography-derived fractional flow reserve in the SYNTAXⅡ trial: feasibility, diagnostic performance of quantitative flow ratio, and clinical prognostic value of functional SYNTAX score derived from quantitative flow ratio in patients with 3-vessel disease . JACC Cardiovasc Interv 2019 ;12( 3 ): 259 - 70 . doi: 10.1016/j.jcin.2018.09.023 https://dx.doi.org/10.1016/j.jcin.2018.09.023 . DOI: 10.1016/j.jcin.2018.09.023 http://doi.org/10.1016/j.jcin.2018.09.023

Zhang R , Song C , Guan C , et al . Prognostic value of quantitative flow ratio based functional SYNTAX score in patients with left main or multivessel coronary artery disease . Circ Cardiovasc Interv 2020 ; 13 ( 10 ): e009 155. doi: 10.1161/circinterventions.120.009155 https://dx.doi.org/10.1161/circinterventions.120.009155 . DOI: 10.1161/circinterventions.120.009155 http://doi.org/10.1161/circinterventions.120.009155

Sonck J , Miyazaki Y , Collet C , et al . Feasibility of planning coronary artery bypass grafting based only on coronary computed tomography angiography and CT-derived fractional flow reserve: a pilot survey of the surgeons involved in the randomized SYNTAX Ⅲ revolution trial . Interact Cardiovasc Thorac Surg 2019 ; 29 ( 2 ): 209 - 16 . doi: 10.1093/icvts/ivz046 https://dx.doi.org/10.1093/icvts/ivz046 . DOI: 10.1093/icvts/ivz046 http://doi.org/10.1093/icvts/ivz046 https://academic.oup.com/icvts/article/29/2/209/5385515 https://academic.oup.com/icvts/article/29/2/209/5385515

Kerner A , Abadi S , Abergel E , et al . Direct comparison between coronary computed tomography and invasive angiography for calculation of SYNTAX score . EuroIntervention 2013 ; 8 ( 12 ): 1428 - 34 . doi: 10.4244/eijv8i12a216 https://dx.doi.org/10.4244/eijv8i12a216 . DOI: 10.4244/EIJV8I12A216 http://doi.org/10.4244/EIJV8I12A216

Collet C , Onuma Y , Andreini D , et al . Coronary computed tomography angiography for heart team decision-making in multivessel coronary artery disease . Eur Heart J 2018 ; 39 ( 41 ): 3689 - 98 . doi: 10.1093/eurheartj/ehy581 https://dx.doi.org/10.1093/eurheartj/ehy581 . DOI: 10.1093/eurheartj/ehy581 http://doi.org/10.1093/eurheartj/ehy581

Modolo R , Collet C , Onuma Y , et al . SYNTAX Ⅱ and SYNTAX Ⅲ trials: what is the take home message for surgeons? Ann Cardiothorac Surg 2018 ;7( 4 ): 470 - 82 . doi: 10.21037/acs.2018.07.02 https://dx.doi.org/10.21037/acs.2018.07.02 . DOI: 10.21037/acs.2018.07.02 http://doi.org/10.21037/acs.2018.07.02

Katagiri Y , Andreini D , Miyazaki Y , et al . Site vs . core laboratory variability in computed tomographic angiography-derived SYNTAX scores in the SYNTAX Ⅲ trial . Eur Heart J Cardiovasc Imaging 2021 ; 22 ( 9 ): 1063 - 71 . doi: 10.1093/ehjci/jeaa172 https://dx.doi.org/10.1093/ehjci/jeaa172 . DOI: 10.1093/ehjci/jeaa172 http://doi.org/10.1093/ehjci/jeaa172 https://academic.oup.com/ehjcimaging/article/22/9/1063/5901748 https://academic.oup.com/ehjcimaging/article/22/9/1063/5901748

Nørgaard BL , Gaur S , Leipsic J , et al . Influence of coronary calcification on the diagnostic performance of CT angiography derived FFR in coronary artery disease: a substudy of the NXT trial . JACC Cardiovasc Imaging 2015 ; 8 ( 9 ): 1045 - 55 . doi: 10.1016/j.jcmg.2015.06.003 https://dx.doi.org/10.1016/j.jcmg.2015.06.003 . DOI: S1936-878X(15)00420-9 http://doi.org/S1936-878X(15)00420-9

Nørgaard BL , Leipsic J , Achenbach S . Coronary CT angiography to guide treatment decision making: lessons from the SYNTAX Ⅱ trial . J Am Coll Cardiol 2018 ; 71 ( 24 ): 2770 - 2 . doi: 10.1016/j.jacc.2018.02.052 https://dx.doi.org/10.1016/j.jacc.2018.02.052 . DOI: S0735-1097(18)33491-0 http://doi.org/S0735-1097(18)33491-0

Collet C , Miyazaki Y , Ryan N , et al . Fractional flow reserve derived from computed tomographic angiography in patients with multivessel CAD . J Am Coll Cardiol 2018 ; 71 ( 24 ): 2756 - 69 . doi: 10.1016/j.jacc.2018.02.053 https://dx.doi.org/10.1016/j.jacc.2018.02.053 . DOI: S0735-1097(18)33492-2 http://doi.org/S0735-1097(18)33492-2

Qiao HY , Li JH , Schoepf UJ , et al . Prognostic implication of CT-FFR based functional SYNTAX score in patients with de novo three-vessel disease . Eur Heart J Cardiovasc Imaging 2020 ; 22 ( 12 ): 1434 - 42 . doi: 10.1093/ehjci/jeaa256 https://dx.doi.org/10.1093/ehjci/jeaa256 . DOI: 10.1093/ehjci/jeaa256 http://doi.org/10.1093/ehjci/jeaa256

Nørgaard BL , Leipsic J , Gaur S , et al . Diagnostic performance of noninvasive fractional flow reserve derived from coronary computed tomography angiography in suspected coronary artery disease: the NXT trial (Analysis of Coronary Blood Flow Using CT Angiography: Next Steps) . J Am Coll Cardiol 2014 ; 63 ( 12 ): 1145 - 55 . doi: 10.1016/j.jacc.2013.11.043 https://dx.doi.org/10.1016/j.jacc.2013.11.043 . DOI: S0735-1097(14)00165-X http://doi.org/S0735-1097(14)00165-X

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