Organizing Pneumonia in A Patient Double-Positive for ANCA and Anti-GBM Antibodies: A Case Report

Fang-Yuan Wang; Xiang-Ning Yuan; Dan-Ni Sun; Gong Xiao; Cheng-Huan Hu; Zhong-Hua Liao; Jian-Ping Ning; Hui Xu; Jun-Tao Feng; Hong-Ling Yin; Xiao-Zhao Li

doi:10.24920/004161

Your Location：

Home >

Browse articles >

Organizing Pneumonia in A Patient Double-Positive for ANCA and Anti-GBM Antibodies: A Case Report

Chinese Medical Sciences Journal Vol. 38, Issue 1, Pages: 66-69(2023)

Case Report | Updated：2024-03-30

- Organizing Pneumonia in A Patient Double-Positive for ANCA and Anti-GBM Antibodies: A Case Report
- Affiliations：
  
  1. 1Department of Nephrology, Xiangya Hospital of Central South University, Changsha 410008, Hunan, China
  2. 2Department of Pathology, Xiangya Hospital of Central South University, Changsha 410008, Hunan, China
  3. 3Department of Intensive Care Unit, Xiangya Hospital of Central South University, Changsha 410008, Hunan, China
  4. 4Department of Respiration, Xiangya Hospital of Central South University, Changsha 410008, Hunan, China
- Author bio：
  
  Hong-Ling Yin, E-mail: 2646291051@qq.com.
  *Xiao-Zhao Li, E-mail: lixiaozhao@csu.edu.cn;
- Funds：
- DOI：10.24920/004161
  CLC：
- Received：30 August 2022，
  
  Accepted：2022-12-13，
  
  Published Online：02 February 2023，
  
  Published：31 March 2023
- Accepted：
Scan QR Code
Fang-Yuan Wang, Xiang-Ning Yuan, Dan-Ni Sun, et al. Organizing Pneumonia in A Patient Double-Positive for ANCA and Anti-GBM Antibodies: A Case Report[J]. Chinese medical sciences journal, 2023, 38(1): 66-69.
DOI：

Fang-Yuan Wang, Xiang-Ning Yuan, Dan-Ni Sun, et al. Organizing Pneumonia in A Patient Double-Positive for ANCA and Anti-GBM Antibodies: A Case Report[J]. Chinese medical sciences journal, 2023, 38(1): 66-69. DOI： 10.24920/004161.

摘要

抗肾小球基底膜（anti-glomerular basement membrane，GBM）疾病和抗中性粒细胞胞浆抗体（anti-neutrophil cytoplasmic antibody，ANCA）相关性血管炎（ANCA-associated vasculitis，AAV）都是是肺肾综合征的常见原因。机化性肺炎（organizing pneumonia，OP）是一种特殊的间质性肺疾病，在AAV和抗GBM疾病中都极为罕见。我们报道了一例ANCA和抗GBM抗体双阳性并伴有机化性肺炎的老年女性病例。

Abstract

Both anti-glomerular basement membrane (GBM) disease and the anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) are common causes of pulmonary-renal syndrome. Organizing pneumonia (OP)

a special pattern of interstitial lung disease

is extremely rare either in AAV or anti-GBM disease. We report an old woman presented with OP on a background of co-presentation with both ANCA and anti-GBM antibodies.

关键词

Keywords

references

Sethi S , de Vriese AS , Fervenza FC . Acute glomerulonephritis . Lancet 2022 ; 399 ( 10335 ): 1646 - 63 . doi: 10.1016/S0140-6736(22)00461-5 https://dx.doi.org/10.1016/S0140-6736(22)00461-5 . DOI: 10.1016/S0140-6736(22)00461-5 http://doi.org/10.1016/S0140-6736(22)00461-5

Maillet T , Goletto T , Beltramo G , et al. Usual interstitial pneumonia in ANCA-associated vasculitis: A poor prognostic factor . J Autoimmun 2020 ; 106 : 102338 . doi: 10.1016/j.jaut.2019.102338 https://dx.doi.org/10.1016/j.jaut.2019.102338 . DOI: 10.1016/j.jaut.2019.102338 http://doi.org/10.1016/j.jaut.2019.102338 https://linkinghub.elsevier.com/retrieve/pii/S0896841119304615 https://linkinghub.elsevier.com/retrieve/pii/S0896841119304615

Cherian SV , Patel D , Machnicki S , et al. Algorithmic Approach to the Diagnosis of Organizing Pneumonia: A Correlation of Clinical, Radiologic, and Pathologic Features . Chest 2022 ; 162 ( 1 ): 156 - 78 . doi: 10.1016/j.chest.2021.12.659 https://dx.doi.org/10.1016/j.chest.2021.12.659 . DOI: 10.1016/j.chest.2021.12.659 http://doi.org/10.1016/j.chest.2021.12.659

Imokawa S , Uehara M , Uto T , et al. Organizing pneumonia associated with myeloperoxidase anti-neutrophil cytoplasmic antibody . Respirol Case Rep 2015 ; 3 ( 4 ): 122 - 4 . doi: 10.1002/rcr2.123 https://dx.doi.org/10.1002/rcr2.123 . DOI: 10.1002/rcr2.123 http://doi.org/10.1002/rcr2.123 https://onlinelibrary.wiley.com/toc/20513380/3/4 https://onlinelibrary.wiley.com/toc/20513380/3/4

Takada K , Miyamoto A , Nakahama H , et al. Myeloperoxidase anti-neutrophil cytoplasmic antibody-associated vasculitis with a unique imaging presentation of organizing pneumonia: A case report . Respir Med Case Rep 2020 ; 31 : 101294 . doi: 10.1016/j.rmcr.2020.101294 https://dx.doi.org/10.1016/j.rmcr.2020.101294 . DOI: 10.1016/j.rmcr.2020.101294 http://doi.org/10.1016/j.rmcr.2020.101294

Bae JY , Hussein KI , Leibert E , et al. Seronegative Goodpasture's syndrome associated with organising pneumonia . BMJ Case Rep 2021 ; 14 ( 2 ): e239390 . doi: 10.1136/bcr-2020-239390 https://dx.doi.org/10.1136/bcr-2020-239390 . DOI: 10.1136/bcr-2020-239390 http://doi.org/10.1136/bcr-2020-239390

Philip R , Dumont A , Martin Silva N , et al. ANCA and anti-glomerular basement membrane double-positive patients: A systematic review of the literature . Autoimmun Rev 2021 ; 20 ( 9 ): 102885 . doi: 10.1016/j.autrev.2021.102885 https://dx.doi.org/10.1016/j.autrev.2021.102885 . DOI: 10.1016/j.autrev.2021.102885 http://doi.org/10.1016/j.autrev.2021.102885

McAdoo SP , Pusey CD . Anti-Glomerular Basement Membrane Disease . Clin J Am Soc Nephrol 2017 ; 12 ( 7 ): 1162 - 72 . doi: 10.2215/CJN.01380217 https://dx.doi.org/10.2215/CJN.01380217 . DOI: 10.2215/CJN.01380217 http://doi.org/10.2215/CJN.01380217 https://journals.lww.com/01277230-201707000-00018 https://journals.lww.com/01277230-201707000-00018

Serratrice J , Chiche L , Dussol B , et al. Sequential development of perinuclear ANCA-associated vasculitis and anti-glomerular basement membrane glomerulonephritis . Am J Kidney Dis 2004 ; 43 ( 3 ): e26 - 30 . doi: 10.1053/j.ajkd.2003.11.019 https://dx.doi.org/10.1053/j.ajkd.2003.11.019 . DOI: 10.1053/j.ajkd.2003.11.019 http://doi.org/10.1053/j.ajkd.2003.11.019

McAdoo SP , Tanna A , Hrušková Z , et al. Patients double-seropositive for ANCA and anti-GBM antibodies have varied renal survival, frequency of relapse, and outcomes compared to single-seropositive patients . Kidney Int 2017 ; 92 ( 3 ): 693 - 702 . doi: 10.1016/j.kint.2017.03.014 https://dx.doi.org/10.1016/j.kint.2017.03.014 . DOI: 10.1016/j.kint.2017.03.014 http://doi.org/10.1016/j.kint.2017.03.014 https://linkinghub.elsevier.com/retrieve/pii/S0085253817302077 https://linkinghub.elsevier.com/retrieve/pii/S0085253817302077

Alba MA , Flores-Suárez LF , Henderson AG , et al. Interstital lung disease in ANCA vasculitis . Autoimmun Rev 2017 ; 16 ( 7 ): 722 - 9 . doi: 10.1016/j.autrev.2017.05.008 https://dx.doi.org/10.1016/j.autrev.2017.05.008 . DOI: S1568-9972(17)30128-3 http://doi.org/S1568-9972(17)30128-3

Tashiro H , Takahashi K , Ikeda Y , et al. Pre-existing chronic interstitial pneumonia is a poor prognostic factor of Goodpasture's syndrome: a case report and review of the literature . J Med Case Rep 2017 ; 11 ( 1 ): 102 . doi: 10.1186/s13256-017-1273-8 https://dx.doi.org/10.1186/s13256-017-1273-8 . DOI: 10.1186/s13256-017-1273-8 http://doi.org/10.1186/s13256-017-1273-8

King TE Jr , Lee JS . Cryptogenic Organizing Pneumonia . N Engl J Med 2022 ; 386 ( 11 ): 1058 - 69 . doi: 10.1056/NEJMra2116777 https://dx.doi.org/10.1056/NEJMra2116777 . DOI: 10.1056/NEJMra2116777 http://doi.org/10.1056/NEJMra2116777 http://www.nejm.org/doi/10.1056/NEJMra2116777 http://www.nejm.org/doi/10.1056/NEJMra2116777

Kitching AR , Anders HJ , Basu N , et al. ANCA-associated vasculitis . Nat Rev Dis Primers 2020 ; 6 ( 1 ): 71 . doi: 10.1038/s41572-020-0204-y https://dx.doi.org/10.1038/s41572-020-0204-y . DOI: 10.1038/s41572-020-0204-y http://doi.org/10.1038/s41572-020-0204-y

Views

460

Downloads

CSCD

Alert me when the article has been cited

Submit

Publicity Resources

No data

Related Author

No data

Related Institution

No data

⁰