Diagnostic Accuracy of Computerized Bowel Sound Analysis with Non-Invasive Devices for Irritable Bowel Syndrome: A Systematic Review and Meta-Analysis

Xia-Xiao Yan; Yue-Lun Zhang; Yu-Pei Zhang; Ying-Yun Yang; Dong Wu

doi:10.24920/004307

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Diagnostic Accuracy of Computerized Bowel Sound Analysis with Non-Invasive Devices for Irritable Bowel Syndrome: A Systematic Review and Meta-Analysis

Chinese Medical Sciences Journal Vol. 39, Issue 2, Pages: 122-130(2024)

Research Articles | Updated：2025-03-07

- Diagnostic Accuracy of Computerized Bowel Sound Analysis with Non-Invasive Devices for Irritable Bowel Syndrome: A Systematic Review and Meta-Analysis
- Affiliations：
  
  1.Department of Gastroenterology, State Key Laboratory of Complex Severe and Rare Diseases, Beijing 100730, China
  3.Medical Research Center, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China
  2.Eight-Year Medical Doctor Program, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China
- Author bio：
  
  E-mail: wudong@pumch.cn
- Funds：
  
  国家自然科学基金(32170788);中央高水平医院临研专项(2022-PUMCH-B-023);北京市自然科学基金(7232123)
- DOI：10.24920/004307
  CLC：
- Received：16 October 2023，
  
  Accepted：2024-02-07，
  
  Published Online：10 April 2024，
  
  Published：30 June 2024
- Accepted：
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闫夏晓,张越伦,张钰佩等.无创肠鸣音分析诊断肠易激综合征的准确性：系统综述和荟萃分析[J].中国医学科学杂志（英文）,2024,39(02):122-130.

Yan Xia-Xiao,Zhang Yue-Lun,Zhang Yu-Pei,et al.Diagnostic Accuracy of Computerized Bowel Sound Analysis with Non-Invasive Devices for Irritable Bowel Syndrome: A Systematic Review and Meta-Analysis[J].Chinese Medical Sciences Journal,2024,39(02):122-130.
闫夏晓,张越伦,张钰佩等.无创肠鸣音分析诊断肠易激综合征的准确性：系统综述和荟萃分析[J].中国医学科学杂志（英文）,2024,39(02):122-130. DOI： 10.24920/004307.

Yan Xia-Xiao,Zhang Yue-Lun,Zhang Yu-Pei,et al.Diagnostic Accuracy of Computerized Bowel Sound Analysis with Non-Invasive Devices for Irritable Bowel Syndrome: A Systematic Review and Meta-Analysis[J].Chinese Medical Sciences Journal,2024,39(02):122-130. DOI： 10.24920/004307.

摘要

目的

采用系统回顾和荟萃分析评估肠鸣音分析对肠易激综合征（irritable bowel syndrome，IBS）的诊断准确性。

方法

检索MEDLINE，EMBASE，Cochrane Library，Web of Science和IEEE Xplore数据库中有关肠鸣音分析对IBS诊断准确性的横断面和病例对照研究。检索截止时间为2023年9月。计算灵敏度、特异度、阳性似然比、阴性似然比和诊断比值比及95%置信区间（confidence interval，

），并绘制受试者工作特征曲线，计算曲线下面积。

结果

共纳入4项研究。肠鸣音分析诊断IBS的灵敏度、特异度、阳性似然比、阴性似然比和诊断比值比分别为0.94（95%

，0.87～0.97），0.89（95%

，0.81～0.94），8.43（95%

，4.81～14.78），0.07（95%

，0.03～0.15）和118.86（95%

，44.18～319.75），曲线下面积为 0.97（95%

，0.95～0.98）。

结论

肠鸣音分析是一种诊断IBS的有效工具。然而，由于高质量研究数据有限，结果的真实性和适用性存疑，需要开展更多临床诊断试验，并优化可穿戴设备进行肠鸣音监测和分析。

Abstract

Objective

To assess the diagnostic accuracy of bowel sound analysis for irritable bowel syndrome (IBS) with a systematic review and meta-analysis.

Methods

We searched MEDLINE

Embase

the Cochrane Library

Web of Science

and IEEE Xplore databases until September 2023. Cross-sectional and case-control studies on diagnostic accuracy of bowel sound analysis for IBS were identified. We estimated the pooled sensitivity

specificity

positive likelihood ratio

negative likelihood ratio

and diagnostic odds ratio with a 95% confidence interval (

)

and plotted a summary receiver operating characteristic curve and evaluated the area under the curve.

Results

Four studies were included. The pooled diagnostic sensitivity

specificity

positive likelihood ratio

negative likelihood ratio

and diagnostic odds ratio were 0.94 (95%

0.87‒0.97)

0.89 (95%

0.81‒0.94)

8.43 (95%

4.81‒1

4.78)

0.07 (95%

0.03‒0.15)

and 118.86 (95%

44.18‒319.75)

respectively

with an area under the curve of 0.97 (95%

0.95‒0.98).

Conclusions

Computerized bowel sound analysis is a promising tool for IBS. However

limited high-quality data make the results' validity and applicability questionable. There is a need for more diagnostic test accuracy studies and better wearable devices for monitoring and analysis of IBS.

关键词

Keywords

references

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