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Medication Rules of Hub Herb Pairs for Insomnia and Mechanism of Action: Results of Data Mining, Network Pharmacology, and Molecular Docking
Chinese Medical Sciences Journal   Vol. 39, Issue 4, Pages: 249-260(2024)
Research Articles | Updated：2025-04-16

    • Medication Rules of Hub Herb Pairs for Insomnia and Mechanism of Action: Results of Data Mining, Network Pharmacology, and Molecular Docking

    • “In the field of traditional Chinese medicine for insomnia treatment, this study statistically analyzed 104 prescriptions and identified six hub herb pairs. Network pharmacology revealed that the cAMP signaling pathway might play a key role in treating insomnia synergistically with HIF-1 signaling pathway, prolactin signaling pathway, chemical carcinogenesis receptor activation, and PI3K-Akt signaling pathway.”

    • DOI：10.24920/004384    

      CLC：

    • Received：05 June 2024，

      Accepted：2024-10-24，

      Published Online：26 November 2024，

      Published：31 December 2024

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  • Guo Wen-Long,Jiang Hui-Juan,Li Yan-Rong,et al.Medication Rules of Hub Herb Pairs for Insomnia and Mechanism of Action: Results of Data Mining, Network Pharmacology, and Molecular Docking[J].Chinese Medical Sciences Journal,2024,39(04):249-260. DOI： 10.24920/004384.

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