Cellular senescence refers to a process that cellular proliferation and differentiation modulated by the multiple stimulating factors gradually decline. Aging cells present the irreversible stop of proliferation and differentiation and change in secretory function because the cell cycle of aging cells is steadily blocked at some point. It has have been shown that cellular senescence plays an important role in the occurrence and development of liver diseases. In this paper
we review the advances in relations between cellular senescence and liver diseases.
Progress of Targeting Transforming Growth Factor-β1 Small Interfering RNA in Liver Fibrosis
Related Author
Xuan Zhou
Xue-feng Yang
Yuan-Yuan Wang
Hai-Lian Lin
Ke-Lang Wang
Gen-Xiang Que
Ting Cao
La-Mei Zhu
Related Institution
Department of Gastroenterology, Affiliated Nanhua Hospital, University of South China
Hunan Provincial Clinical Research Center for Metabolic Associated Fatty Liver Disease, Affiliated Nanhua Hospital, Hengyang Medical School & University of South China
Department of Gastroenterology, Affiliated Nanhua Hospital, Hengyang Medical School & University of South China
Department of Hepatobiliary Surgery, Affiliated Nanhua Hospital, Hengyang Medical School & University of South China
Department of General Practice, Affiliated Nanhua Hospital, Hengyang Medical School & University of South China