

FOLLOWUS
Department of Neurosurgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100730 China
Published Online:20 June 2016,
Published:2016-06
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Wang Yu, Liu Zi-yuan, Dou Wan-chen, et al. Application of Preoperative CT/MRI Image Fusion in Target Positioning for Deep Brain Stimulation[J]. Chinese medical sciences journal, 2016, 31(3): 161-167.
Objective
To explore the efficacy of target positioning by preoperative CT/MRI image fusion technique in deep brain stimulation.
Methods
We retrospectively analyzed the clinical data and images of 79 cases (68 with Parkinson’s disease
11 with dystonia) who received preoperative CT/MRI image fusion in target positioning of subthalamic nucleus in deep brain stimulation. Deviation of implanted electrodes from the target nucleus of each patient were measured. Neurological evaluations of each patient before and after the treatment were performed and compared. Complications of the positioning and treatment were recorded.
Results
The mean deviations of the electrodes implanted on X
Y
and Z axis were 0.5 mm
0.6 mm
and 0.6 mm
respectively. Postoperative neurologic evaluations scores of unified Parkinson’s disease rating scale (UPDRS) for Parkinson’s disease and Burke-Fahn-Marsden Dystonia Rating Scale (BFMDRS) for dystonia patients improved significantly compared to the preoperative scores (
P
<
0.001); Complications occurred in 10.1% (8/79) patients
and main side effects were dysarthria and diplopia.
Conclusion
Target positioning by preoperative CT/MRI image fusion technique in deep brain stimulation has high accuracy and good clinical outcomes.
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