Objective In cerebral aneurysm clipping and embolization

blood pressure control and temporary parent artery blocking are common methods to prevent aneurysm rupture. Their influence on the prognosis is uncertain. In this study

we try to find out the association between methods above and prognostic indicators.Methods We held a retrospective analysis on patients’ medical records of cerebral aneurysms surgical clipping and endovascular coiling

and recorded gender

age

diagnosis

Hunt-Hess grade

Glasgow coma scale score

treatment methods

a history of hypertension

preoperative systolic blood pressure

with or without controlled hypotension

systolic blood pressure difference before and after controlled hypotension

with or without temporary artery blocking

with or without hypertension after treated aneurysm

prognostic indicators including mortality after 1 month

intensive care unit (ICU) stay time of survivors

discharged Glasgow outcome scale (GOS) score. Prognostic indicators were regarded as dependent variable

all the factors were regarded as independent variable

and the strength analysis of influence factors on prognostic indicators was made by binary logistic regression.Results Total cases were 165

including 68 males and 97 females

with an average age of 56 (12-85) years. The mortality after 1 month was 10.9% (18 cases). The ICU stay time of survivors was 7.35 (0-67) days. GOS score at discharge was 1-3 in 40 (24.2%) patients and 4-5 in 125 (75.8%) patients. Systolic blood pressure difference before and after controlled hypotension was an independent factor influencing mortality (=2.273

0.024)

and the greater the difference was

the higher the mortality would be. Timely hypertension after aneurysm treated was an independent factor affecting ICU stay time of survivors and patients with hypertension had shorter ICU stay time (=10.017

0.001). Blood pressure control (=0.088

0.767) and temporary blocking (=1.307

0.253) did not show significant influence on GOS score at discharge.Conclusions Timely controlled hypertension after aneurysm clipping and embolization can significantly shorten the stay time in ICU. The degree of controlled hypotension associates with postoperative mortality

the greater systolic blood pressure difference before and after antihypertensive treatment is

the higher the mortality will be.