Objective To explore the feasibility and efficiency of a novel magnetic compression anastomats (MCAs) in intestinal anastomosis.  Methods A total of 36 male mongrel canines underwent intestinal anastomosis using traditional hand-sewn (n=18) or a novel MCAs (n=18). We compared the anastomosis time

postoperative complica-tions

bursting strength of anastomoses

gross appearance

and pathology between two groups at each time- point of follow-up.  Results The mean anastomosis time with MCAs was significantly less than that with hand-sewn (8.50±1.95 vs. 31.1±4.32 minutes

P<0.001). The blood stools and intussusceptions occurred in both groups during follow-up period. Only 1 mongrel canine receiving intestinal anastomosis by MCAs experi-enced anastomotic leakage. The average bursting pressure of anastomoses obtained from mongrel canines undergoing intestinal anastomosis by MCAs was significantly higher than that by traditional hand-sewn at 1 week’s follow-up time (P<0.05). Gross appearance of the anastomoses constructed by MCAs was relatively smoother and flatter. Pathological evalution of anastomoses revealed that general inflammation was greater in hand-sewn anastomoses than magnetic anastomosis.  Conclusion The magnetic compression anastomat is a safe and effective device of sutureless intesti-nal anastomosis in canine models.