

FOLLOWUS
1. Department of Radiology
2. PLA General Hospital
3. Department of Neurology
4. PLA General Hospital Beijing,100853
Published:2003
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[1]马林,蔡幼铨,梁丽,郭行高,于生元.MR IMAGING OF MENINGEAL CARCINOMATOSIS BY SYSTEMIC MALIGNANCY[J].Chinese Medical Sciences Journal,2003(01):36-40.
MR IMAGING OF MENINGEAL CARCINOMATOSIS BY SYSTEMIC MALIGNANCY[J]. Chinese medical sciences journal, 2003, (1): 36-40.
<正> Objective. To investigate the magnetic resonance (MR) features of meningeal carcinomatosis
and to improve the ability in understanding and diagnosing meningeal carcinomatosis by MR findings.Methods. Eleven cases with proven meningeal carcinomatosis were studied by conventional and Gd - DTPA enhanced MR imaging. The enhancement patterns and features
as well as the types of meningeal involvement
were retrospectively analyzed.Results. Conventional MR imaging showed no evident meningeal abnormalities. After the administration of Gd - DTPA
abnormal pia mater enhancement was detected in 9 cases
demonstrating as the continuous
thin
and lineal high signal intensity on the brain surface that could descend into the sulci. The abnormal pial enhancement occurred on the cortical surfaces of cerebellum
brainstem
and cerebrum. No abnormal enhancement in the subarach-noid space was found. Abnormal dura - arachnoid enhancement was seen in 3 cases
showing as the continuous
thick
and curvilineal high signal in
Objective. To investigate the magnetic resonance (MR) features of meningeal carcinomatosis
and to improve the ability in understanding and diagnosing meningeal carcinomatosis by MR findings.Methods. Eleven cases with proven meningeal carcinomatosis were studied by conventional and Gd - DTPA enhanced MR imaging. The enhancement patterns and features
as well as the types of meningeal involvement
were retrospectively analyzed.Results. Conventional MR imaging showed no evident meningeal abnormalities. After the administration of Gd - DTPA
abnormal pia mater enhancement was detected in 9 cases
demonstrating as the continuous
thin
and lineal high signal intensity on the brain surface that could descend into the sulci. The abnormal pial enhancement occurred on the cortical surfaces of cerebellum
brainstem
and cerebrum. No abnormal enhancement in the subarach-noid space was found. Abnormal dura - arachnoid enhancement was seen in 3 cases
showing as the continuous
thick
and curvilineal high signal intensity over the convexities or in the tentorium without extension into the cortical sulci. Cerebral dura - arachnoid involvement was found in all 3 cases and one of them also showed abnormal enhancement in cerebellar dura - arachnoid and tentorium. Of the 11 cases
9 with pial involvement had abnormal cerebrospinal fluid (CSF) results
2 involving only the dura - arachnoid had normal CSF results.Conclusion. Meningeal carcinomatosis could be well demonstrated by Gd - DTPA enhanced MR imaging
and its type could be differentiated by the enhancement features. Combined with the clinical information
Gd - enhanced MR imaging may lead to the diagnosis and guide the therapy of meningeal carcinomatosis.
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