ROLE OF  ENDOGENOUS CARBON  MONOXIDE IN ENDOTOXIN  SHOCK

Your Location：

Home >

Browse articles >

ROLE OF ENDOGENOUS CARBON MONOXIDE IN ENDOTOXIN SHOCK

Chinese Medical Sciences Journal Vol. 0, Issue 2, Pages: 98-102(2000)

Updated：2024-04-10

- ROLE OF ENDOGENOUS CARBON MONOXIDE IN ENDOTOXIN SHOCK
- Affiliations：
- Author bio：
- Funds：
- DOI：
  CLC： R364.14
- Published：2000
- Accepted：
Scan QR Code
ROLE OF ENDOGENOUS CARBON MONOXIDE IN ENDOTOXIN SHOCK[J]. Chinese medical sciences journal, 2000, 0(2): 98-102.
DOI：

ROLE OF ENDOGENOUS CARBON MONOXIDE IN ENDOTOXIN SHOCK[J]. Chinese medical sciences journal, 2000, 0(2): 98-102. DOI：

摘要

Abstract

Objective.To study the role of endogenous carbon monoxide （CO） in endotoxin shock. Methods. The changes of CO levels and the effects of zinc protoporphyrin IX （ZnPP）

an inhibitor of hemeoxygenase （HO）

in endotoxin shock and the efficacy of hemin

an inducer of HO were investigated. Results.The plasma CO levels were found to be significantly increased during the course of endotoxin shock. Injection of ZnPP was shown to abrogate the endotoxininduced hypotension and metabolic derangements markedly. Administration of hemin to healthy rabbits revealed the hypotension and metabolic derangements similar to the animals given endotoxin. Conclusion.CO is a newly found endogenously produced mediator which may play an important role in the pathogenesis of endotoxin shock.

关键词

Keywords

references

Views

Downloads

CSCD

Alert me when the article has been cited

Submit

Publicity Resources

EVIDENCE OF INCREASED ENDOGENOUS CARBON MONOXIDE PRODUCTION IN NEWBORN RAT ENDOTOXICOSIS

ENDOGENOUS HEME OXYGENASE/CARBON MONOXIDE SYSTEM MEDIATES LIPOPOLYSACCHARIDE-INDUCED INTUSSUSCEPTION IN RATS

Related Author

No data

Related Institution

No data

⁰