AN ASSOCIATION STUDY BETWEEN ESSENTIAL HYPERTENSION AND HLA-DRB1 ALLELES

Tao Zhenyin; Zhao Yan; Zhu Xilin; Zhu Ke; Yu Guoping; Wu Weipin; Dong yi; Liu Lisheng and Qiu Cahngchun

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AN ASSOCIATION STUDY BETWEEN ESSENTIAL HYPERTENSION AND HLA-DRB1 ALLELES

Chinese Medical Sciences Journal Issue 2, (1995)

Updated：2024-04-10

- AN ASSOCIATION STUDY BETWEEN ESSENTIAL HYPERTENSION AND HLA-DRB1 ALLELES
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  CLC： R363
- Published：1995
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[1]陶贞寅,赵岩,朱席林,朱克,余国平,吴卫平,董怡,刘力生,邱长春.AN ASSOCIATION STUDY BETWEEN ESSENTIAL HYPERTENSION AND HLA-DRB1 ALLELES[J].Chinese Medical Sciences Journal,1995(02):70-72.

Tao Zhenyin, Zhao Yan, Zhu Xilin, et al. AN ASSOCIATION STUDY BETWEEN ESSENTIAL HYPERTENSION AND HLA-DRB1 ALLELES[J]. Chinese medical sciences journal, 1995, (2).
[1]陶贞寅,赵岩,朱席林,朱克,余国平,吴卫平,董怡,刘力生,邱长春.AN ASSOCIATION STUDY BETWEEN ESSENTIAL HYPERTENSION AND HLA-DRB1 ALLELES[J].Chinese Medical Sciences Journal,1995(02):70-72. DOI：

Tao Zhenyin, Zhao Yan, Zhu Xilin, et al. AN ASSOCIATION STUDY BETWEEN ESSENTIAL HYPERTENSION AND HLA-DRB1 ALLELES[J]. Chinese medical sciences journal, 1995, (2). DOI：

摘要

ＡＮＡＳＳＯＣＩＡＴＩＯＮＳＴＵＤＹＢＥＴＷＥＥＮＥＳＳＥＮＴＩＡＬＨＹＰＥＲＴＥＮＳＩＯＮＡＮＤＨＬＡ－ＤＲＢ１ＡＬＬＥＬＥＳＴａｏＺｈｅｎｙｉｎ（陶贞寅）；ＺｈａｏＹａｎ（赵岩）；ＺｈｕＸｉｌｉｎ（朱席林）；ＺｈｕＫｅ（朱克）；ＹｕＧｕｏｐｉｎｇ...

Abstract

It is well established that genetic and environmental factors are involved in the etiology of essential hypertension（EH）. Previous studies have suggested that at least one of the HLA genes is responsible for the genetic susceptibility to EH. Our aim in the present study was to investigate this issue in China by the PCR-SSP HLA-DRB1 typing method. The results showed an increased frequency of HLA-DR2 and a decreased frequency of HLA-DR7 with EH patients compared with controls. We consider that HLA-DR2 may represent a marker for susceptibility to FH in the North Chinese population.

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