RADIOIMMUNOIMAGING OF HUMAN BREAST CANCER XENOGRAFTS IN NUDE MICE BY USING HUMAN ANTI-HUMAN BREAST CANCER MONOCLONAL ANTIBODIES
Chinese Medical Sciences JournalIssue 2, Pages: 80-83(1997)
Updated:2024-04-10
|
Share with wechat friends or circle of friends
Export references
RADIOIMMUNOIMAGING OF HUMAN BREAST CANCER XENOGRAFTS IN NUDE MICE BY USING HUMAN ANTI-HUMAN BREAST CANCER MONOCLONAL ANTIBODIES
Affiliations:
1. Department of Surgery
2. Peking Union Medical College Hospital
3. CAMS & PUMC
4. ,China
5. Department of Microbiology and Immunology
6. Institute of Basic Medical Sciences
Author bio:
Funds:
DOI:
CLC:R737.9
Published:1997
Accepted:
Scan QR Code
[1]孙强,王树蕙,黄汉源,杨子毅,朱预.RADIOIMMUNOIMAGING OF HUMAN BREAST CANCER XENOGRAFTS IN NUDE MICE BY USING HUMAN ANTI-HUMAN BREAST CANCER MONOCLONAL ANTIBODIES[J].Chinese Medical Sciences Journal,1997(02):80-83.
RADIOIMMUNOIMAGING OF HUMAN BREAST CANCER XENOGRAFTS IN NUDE MICE BY USING HUMAN ANTI-HUMAN BREAST CANCER MONOCLONAL ANTIBODIES[J]. Chinese medical sciences journal, 1997, (2): 80-83.
[1]孙强,王树蕙,黄汉源,杨子毅,朱预.RADIOIMMUNOIMAGING OF HUMAN BREAST CANCER XENOGRAFTS IN NUDE MICE BY USING HUMAN ANTI-HUMAN BREAST CANCER MONOCLONAL ANTIBODIES[J].Chinese Medical Sciences Journal,1997(02):80-83.DOI:
RADIOIMMUNOIMAGING OF HUMAN BREAST CANCER XENOGRAFTS IN NUDE MICE BY USING HUMAN ANTI-HUMAN BREAST CANCER MONOCLONAL ANTIBODIES[J]. Chinese medical sciences journal, 1997, (2): 80-83.DOI:
RADIOIMMUNOIMAGING OF HUMAN BREAST CANCER XENOGRAFTS IN NUDE MICE BY USING HUMAN ANTI-HUMAN BREAST CANCER MONOCLONAL ANTIBODIES
摘要
<正> In this study
the human breast cancer-bearing nude mice model has been established and the radioim-munoimaging was carried out by using human anti-human monoclonal antibodies. The results showed that the breast tumor-bearing nude mice received 131I-McAb-CM-l had a clear image of the xenograft during 4 to 6 days after injection and at the same time T/NT all over 1. 0. The highest T/NT reached 7.1. It demonstrates that McAb-CM-1 can specially combine with breast cancer tissues and hopefully it could be used clinically to improve accurate rate of the early breast cancer diagnosis.
Abstract
In this study
the human breast cancer-bearing nude mice model has been established and the radioim-munoimaging was carried out by using human anti-human monoclonal antibodies. The results showed that the breast tumor-bearing nude mice received 131I-McAb-CM-l had a clear image of the xenograft during 4 to 6 days after injection and at the same time T/NT all over 1. 0. The highest T/NT reached 7.1. It demonstrates that McAb-CM-1 can specially combine with breast cancer tissues and hopefully it could be used clinically to improve accurate rate of the early breast cancer diagnosis.