MUTATION OF p53 GENE IN TRANSFORMED RAT TRACHEAL EPITHELIAL CELLS INDUCED BY RADIATION

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MUTATION OF p53 GENE IN TRANSFORMED RAT TRACHEAL EPITHELIAL CELLS INDUCED BY RADIATION

Chinese Medical Sciences Journal Vol. 0, Issue 3, Pages: 158-160(1998)

Updated：2024-04-10

- MUTATION OF p53 GENE IN TRANSFORMED RAT TRACHEAL EPITHELIAL CELLS INDUCED BY RADIATION
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  CLC： R394
- Published：1998
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MUTATION OF p53 GENE IN TRANSFORMED RAT TRACHEAL EPITHELIAL CELLS INDUCED BY RADIATION[J]. Chinese medical sciences journal, 1998, 0(3): 158-160.
DOI：

MUTATION OF p53 GENE IN TRANSFORMED RAT TRACHEAL EPITHELIAL CELLS INDUCED BY RADIATION[J]. Chinese medical sciences journal, 1998, 0(3): 158-160. DOI：

摘要

Abstract

The highly conserved domain （exon 5-8） of p

gene in transformed rat tracheal epithelial （RTE） cells was analyzed by means of polymerase chain reaction and single strand con formation polymorphism （PCR-SSCP）. The result showed that single strand of exon 8 gene had mobility shift in polyacrylamide nondenaturing gel. DNA sequencing proved the mutation was G→C transversion at condon 265.

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