SEROPREVALENCE OF HUMAN HERPESVIRUS-6 IN HEALTHY POPULATION IN TWO PROVINCES OF NORTH CHINA

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SEROPREVALENCE OF HUMAN HERPESVIRUS-6 IN HEALTHY POPULATION IN TWO PROVINCES OF NORTH CHINA

Chinese Medical Sciences Journal Issue 2, Pages: 111-114(1997)

Updated：2024-04-10

- SEROPREVALENCE OF HUMAN HERPESVIRUS-6 IN HEALTHY POPULATION IN TWO PROVINCES OF NORTH CHINA
- Affiliations：
  
  1. Institute of Basic Medical Sciences
  2. CAMS & PUMC
  3. ,China
- Author bio：
- Funds：
- DOI：
  CLC： R181.3
- Published：1997
- Accepted：
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[1]乌正赉,沐桂藩,王璐.SEROPREVALENCE OF HUMAN HERPESVIRUS-6 IN HEALTHY POPULATION IN TWO PROVINCES OF NORTH CHINA[J].Chinese Medical Sciences Journal,1997(02):111-114.

SEROPREVALENCE OF HUMAN HERPESVIRUS-6 IN HEALTHY POPULATION IN TWO PROVINCES OF NORTH CHINA[J]. Chinese medical sciences journal, 1997, (2): 111-114.
[1]乌正赉,沐桂藩,王璐.SEROPREVALENCE OF HUMAN HERPESVIRUS-6 IN HEALTHY POPULATION IN TWO PROVINCES OF NORTH CHINA[J].Chinese Medical Sciences Journal,1997(02):111-114. DOI：

SEROPREVALENCE OF HUMAN HERPESVIRUS-6 IN HEALTHY POPULATION IN TWO PROVINCES OF NORTH CHINA[J]. Chinese medical sciences journal, 1997, (2): 111-114. DOI：

摘要

<正> Background. Human herpesvirus-6 （HHV-6） infection is ubiquitous in selected population with sero-prevalence of 60-80%. Little is known for that in China

except few sporadic studies. To understand prevalence of HHV-6 antibody in Chinese population

this seroepidemiological study was conducted.Methods. Sera were collected from 430 healthy persons and donors living in North China

and tested for HHV-6 antibodies using IFA with HHV-6 GS strain passaged on HSB-2 cells as antigen

and titer e-qual or higher than 1:10 was regarded as seropositive.Results. Of the 430 serum samples tested

297 （69.1%） were positive for HHV-6 IgG. Both seropositive rate and GMT in females were significantly higher than those in males

with X2 = 7. 05

P<0. 01 and F = 7.23

P<0. 01

respectively. Statistically significant difference in prevalence of HHV-6 antibody among various age groups was observed in both sexes

with X2=20. 08 and 20. 28

P = 0. 04

respectively

and young children had a higher titer than adults. But

no significant dif

Abstract

Background. Human herpesvirus-6 （HHV-6） infection is ubiquitous in selected population with sero-prevalence of 60-80%. Little is known for that in China

except few sporadic studies. To understand prevalence of HHV-6 antibody in Chinese population

this seroepidemiological study was conducted.Methods. Sera were collected from 430 healthy persons and donors living in North China

and tested for HHV-6 antibodies using IFA with HHV-6 GS strain passaged on HSB-2 cells as antigen

and titer e-qual or higher than 1:10 was regarded as seropositive.Results. Of the 430 serum samples tested

297 （69.1%） were positive for HHV-6 IgG. Both seropositive rate and GMT in females were significantly higher than those in males

with X2 = 7. 05

P<0. 01 and F = 7.23

P<0. 01

respectively. Statistically significant difference in prevalence of HHV-6 antibody among various age groups was observed in both sexes

with X2=20. 08 and 20. 28

P = 0. 04

respectively

and young children had a higher titer than adults. But

no significant difference in prevalence was observed in blood donors between various age groups or both sexes.Conclusions. This study suggests that HHV-6 infection with seropositive IgG is ubiquitous in North China

and its importance should be further studied.

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