EFFECTS OF β-ENDORPHIN ON PHYTOHEMAGGLUTININ-INDUCED LYMPHOCYTE PROLIFERATION AND MOUSE PLAQUE-FORMING CELL RESPONSE VIA AN OPIOID RECEPTOR MECHANISM

Lin Jiayou; Lu Gang and Weng Jiayu

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EFFECTS OF β-ENDORPHIN ON PHYTOHEMAGGLUTININ-INDUCED LYMPHOCYTE PROLIFERATION AND MOUSE PLAQUE-FORMING CELL RESPONSE VIA AN OPIOID RECEPTOR MECHANISM

Chinese Medical Sciences Journal Issue 4, (1994)

Updated：2024-04-10

- EFFECTS OF β-ENDORPHIN ON PHYTOHEMAGGLUTININ-INDUCED LYMPHOCYTE PROLIFERATION AND MOUSE PLAQUE-FORMING CELL RESPONSE VIA AN OPIOID RECEPTOR MECHANISM
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  CLC： R363
- Published：1994
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[1]林嘉友,鲁刚,翁佳玉.EFFECTS　OF　β－ENDORPHIN　ON　PHYTOHEMAGGLUTININ－INDUCED　LYMPHOCYTE　PROLIFERATION　AND　MOUSE　PLAQUE－FORMING　CELL　RESPONSE　VIA　AN　O[J].Chinese Medical Sciences Journal,1994(04):245-247.

Lin Jiayou, Lu Gang and Weng Jiayu. EFFECTS OF β-ENDORPHIN ON PHYTOHEMAGGLUTININ-INDUCED LYMPHOCYTE PROLIFERATION AND MOUSE PLAQUE-FORMING CELL RESPONSE VIA AN OPIOID RECEPTOR MECHANISM[J]. Chinese medical sciences journal, 1994, (4).
[1]林嘉友,鲁刚,翁佳玉.EFFECTS　OF　β－ENDORPHIN　ON　PHYTOHEMAGGLUTININ－INDUCED　LYMPHOCYTE　PROLIFERATION　AND　MOUSE　PLAQUE－FORMING　CELL　RESPONSE　VIA　AN　O[J].Chinese Medical Sciences Journal,1994(04):245-247. DOI：

Lin Jiayou, Lu Gang and Weng Jiayu. EFFECTS OF β-ENDORPHIN ON PHYTOHEMAGGLUTININ-INDUCED LYMPHOCYTE PROLIFERATION AND MOUSE PLAQUE-FORMING CELL RESPONSE VIA AN OPIOID RECEPTOR MECHANISM[J]. Chinese medical sciences journal, 1994, (4). DOI：

摘要

ＥＦＦＥＣＴＳＯＦβ－ＥＮＤＯＲＰＨＩＮＯＮＰＨＹＴＯＨＥＭＡＧＧＬＵＴＩＮＩＮ－ＩＮＤＵＣＥＤＬＹＭＰＨＯＣＹＴＥＰＲＯＬＩＦＥＲＡＴＩＯＮＡＮＤＭＯＵＳＥＰＬＡＱＵＥ－ＦＯＲＭＩＮＧＣＥＬＬＲＥＳＰＯＮＳＥＶＩＡＡＮＯＰＩＯＩＤＲＥＣＥＰＴＯＲＭ...

Abstract

The effects of opioid peptides on iminune responses were investigated. It was found that β-endorphin （β-END） can depress proliferative responses to PHA in rat splenocytes but enhance those in mice

and it could also inhibit the plaque-forming cell （PFC） response to sheep red blood cells when mouse splenocytes immunized in vivo were cultured in vitro with the peptide. The peptide antagonist naloxone was able to reverse β-END suppression of the PFC response. The data indicate that β-END suppresses antibody production or secretion via a specific opioidreceptor-mediated mechanism.

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