EFFECT OF THREE-YEAR MULTIDRUG THERAPY IN MULTIBACILLARY LEPROSY PATIENTS

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EFFECT OF THREE-YEAR MULTIDRUG THERAPY IN MULTIBACILLARY LEPROSY PATIENTS

Chinese Medical Sciences Journal Issue 1, Pages: 37-40(1990)

Updated：2024-04-10

- EFFECT OF THREE-YEAR MULTIDRUG THERAPY IN MULTIBACILLARY LEPROSY PATIENTS
- Affiliations：
  
  1. Station for Skin Diseases Control,Dongtai County,Jiangsu Province
  2. ,China
  3. Station for Skin Diseases Control
  4. Dongtai County
- Author bio：
- Funds：
- DOI：
  CLC：
- Published：1990
- Accepted：
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[1]李文忠,叶干运,杨忠民,陶明波,骆钧,王传基,季峰.EFFECT OF THREE-YEAR MULTIDRUG THERAPY IN MULTIBACILLARY LEPROSY PATIENTS[J].Chinese Medical Sciences Journal,1990(01):37-40.

EFFECT OF THREE-YEAR MULTIDRUG THERAPY IN MULTIBACILLARY LEPROSY PATIENTS[J]. Chinese medical sciences journal, 1990, (1): 37-40.
[1]李文忠,叶干运,杨忠民,陶明波,骆钧,王传基,季峰.EFFECT OF THREE-YEAR MULTIDRUG THERAPY IN MULTIBACILLARY LEPROSY PATIENTS[J].Chinese Medical Sciences Journal,1990(01):37-40. DOI：

EFFECT OF THREE-YEAR MULTIDRUG THERAPY IN MULTIBACILLARY LEPROSY PATIENTS[J]. Chinese medical sciences journal, 1990, (1): 37-40. DOI：

摘要

<正> The feasibility and effects of a 3-year treatment using rifampicin（RFP）

clofazimine（B663）and dapsone（DDS）in multibacillary leprosy patients in Yangzhou Prefecture and DongtaiCounty（1983-1986）are reported.Among 591 active multibaeillary leprosy patients in thetwo areas

569 （96.30%）were treated with this regimen.of 303 cases available for analysis

196（64.7%）cases showed negative skin smears and clinical inactivity.The rest showeddifferent degrees of improvement.The average reduction of BI was 0.78.The intensityand frequency of ENL and neuritis decreased markedly with treatment.The main side-effects were pigmentation and ichthyosiform changes of the skin

but these did not influencetreatment.

Abstract

The feasibility and effects of a 3-year treatment using rifampicin（RFP）

clofazimine（B663） and dapsone（DDS）in multibacillary leprosy patients in Yangzhou Prefecture and Dongtai County（1983-1986）are reported.Among 591 active multibaeillary leprosy patients in the two areas

569 （96.30%）were treated with this regimen.of 303 cases available for analysis

196（64.7%）cases showed negative skin smears and clinical inactivity.The rest showed different degrees of improvement.The average reduction of BI was 0.78.The intensity and frequency of ENL and neuritis decreased markedly with treatment.The main side- effects were pigmentation and ichthyosiform changes of the skin

but these did not influence treatment.

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