EXPRESSION OF HLA-CLASS Ⅱ GENES OF IDDM PATIENTS ON THE SURFACE OF THE LTK￣- CELLS

Wang Heng and Sun Qi

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EXPRESSION OF HLA-CLASS Ⅱ GENES OF IDDM PATIENTS ON THE SURFACE OF THE LTK￣- CELLS

Chinese Medical Sciences Journal Issue 2, (1994)

Updated：2024-04-10

- EXPRESSION OF HLA-CLASS Ⅱ GENES OF IDDM PATIENTS ON THE SURFACE OF THE LTK￣- CELLS
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  CLC： R363
- Published：1994
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[1]王姮,孙琦.EXPRESSION　OF　HLA－CLASS　Ⅱ　GENES　OF　IDDM　PATIENTS　ON　THE　SURFACE　OF　THE　LTK~－　CELLS[J].Chinese Medical Sciences Journal,1994(02):108-109.

Wang Heng and Sun Qi. EXPRESSION OF HLA-CLASS Ⅱ GENES OF IDDM PATIENTS ON THE SURFACE OF THE LTK￣- CELLS[J]. Chinese medical sciences journal, 1994, (2).
[1]王姮,孙琦.EXPRESSION　OF　HLA－CLASS　Ⅱ　GENES　OF　IDDM　PATIENTS　ON　THE　SURFACE　OF　THE　LTK~－　CELLS[J].Chinese Medical Sciences Journal,1994(02):108-109. DOI：

Wang Heng and Sun Qi. EXPRESSION OF HLA-CLASS Ⅱ GENES OF IDDM PATIENTS ON THE SURFACE OF THE LTK￣- CELLS[J]. Chinese medical sciences journal, 1994, (2). DOI：

摘要

ＥＸＰＲＥＳＳＩＯＮＯＦＨＬＡ－ＣＬＡＳＳⅡＧＥＮＥＳＯＦＩＤＤＭＰＡＴＩＥＮＴＳＯＮＴＨＥＳＵＲＦＡＣＥＯＦＴＨＥＬＴＫ

－

ＣＥＬＬＳ￥ＷａｎｇＨｅｎｇ（王姮）ａｎｄＳｕｎＱｉ（孙琦）(ＰＵＭＣＨｏｓｐｉｔａｌ，ＣＡＭＳ＆ＰＵＭＣ，Ｂｅｉｊｉｎｇ１?..

Abstract

To investigate the function of HLA-class Ⅱ genes in the autoimmune response of insulin dependent diabetes mellitus（IDDM）

the HLA-class Ⅱ gene of IDDM patients was introduced into Ltk-cells with pSV2-neo plasmid

using the calcium phosphate precipitation technique. We obtained a stable cell line expressing the HLA-class Ⅱ gene from lymphocytes of IDDM patients. Expression was identified by direct ox erythocyte-CrCl3-HLA DR monoclonal antibody rosetting.

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