MRI Histogram Texture Feature Analysis of the Optic Nerve in the Patients with Optic Neuritis

Liu Hongjuan; Zhou Huanfen; Zong Linxiong; Liu Mengqi; Wei Shihui; Chen Zhiye

doi:10.24920/003507

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MRI Histogram Texture Feature Analysis of the Optic Nerve in the Patients with Optic Neuritis

Chinese Medical Sciences Journal Vol. 34, Issue 1, Pages: 18-23(2019)

Original Articles | Updated：2024-04-10

- MRI Histogram Texture Feature Analysis of the Optic Nerve in the Patients with Optic Neuritis
- Affiliations：
  
  1. Department of Ophthalmology,Chinese PLA General Hospital, Beijing 100853, China
  2. Department of Radiology, Hainan Hospital of Chinese PLA General Hospital, Sanya, Hainan 572013, China
  3. Department of Radiology, Chinese PLA General Hospital, Beijing 100853, China
- Author bio：
  
  * Tel: 86-898-37330852, E-mail: yyqf@hotmail.com
- Funds：
- DOI：10.24920/003507
  CLC：
- Received：12 September 2018，
  
  Revised：22 February 2019，
  
  Published Online：30 March 2019，
  
  Published：30 March 2019
- Accepted：
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Liu Hongjuan, Zhou Huanfen, Zong Linxiong, et al. MRI Histogram Texture Feature Analysis of the Optic Nerve in the Patients with Optic Neuritis[J]. Chinese medical sciences journal, 2019, 34(1): 18-23.
DOI：

Liu Hongjuan, Zhou Huanfen, Zong Linxiong, et al. MRI Histogram Texture Feature Analysis of the Optic Nerve in the Patients with Optic Neuritis[J]. Chinese medical sciences journal, 2019, 34(1): 18-23. DOI： 10.24920/003507.

摘要

目的

采用磁共振直方图分析对视神经炎患者视神经损伤进行评估。

方法

本研究共纳入60例视神经炎患者及20名正常对照。采用冠状位脂肪抑制T2加权成像及增强T1加权成像评估视神经。提取受累视神经在相应的冠状位T2加权成像病变部位磁共振直方图纹理特征，而对于正常视神经，提取视神经后1/3处的纹理特征。采用Kruskal-Wallis单因素方差分析比较组间纹理差异，采用受试者工作特征曲线（receiver operating characteristic curve，ROC）评估纹理特征参数在强化的受累视神经（the optic nerve with enhancement，ONwEN），不强化的受累视神经（optic nerve without enhancement，ONwoEN），看似正常视神经（normal appearing optic nerve，NAON)）及正常视神经组（normal optic nerve，NON）间视神经损害评估中的诊断价值。

结果

直方图纹理参数能量及熵在ONwEN比ONwoEN（

= 0.000），ONwEN比NON（

= 0.000）及 NAON比NON（

= 0.010）组间的差异具有统计学意义。在ONwEN与ONwoEN组间，直方图显示能量及熵的ROC曲线下面积分别为0.758及0.795；在ONwEN和NON组间，能量及熵的ROC曲线下面积分别为0.758及0.795；在NAON和NON组间能量及熵的ROC曲线下面积分别为0.701及0.707。

结论

磁共振直方图纹理特征参数能量及熵的变化可以用来替代磁共振增强扫描评估视神经炎患者的受累视神经及看似正常视神经损伤。

Abstract

Objective

To evaluate the optic nerve impairment using MRI histogram texture analysis in the patients with optic neuritis.

Methods

The study included 60 patients with optic neuritis and 20 normal controls. The coronal T2 weighted imaging (T2WI) with fat saturation and enhanced T1 weighted imaging (T1WI) were performed to evaluate the optic nerve. MRI histogram texture features of the involved optic nerve were measured on the corresponding coronal T2WI images. The normal optic nerve (NON) was measured in the posterior 1/3 parts of the optic nerve. Kruskal-Wallis one-way

ANOVA

was used to compare the difference of texture features and receiver operating characteristic (ROC) curve were performed to evaluate the diagnostic value of texture features for the optic nerve impairment among the affected optic nerve with enhancement (ONwEN)

affected optic nerve without enhancement (ONwoEN)

contralateral normal appearing optic nerve (NAON) and NON.

Results

The histogram texture Energy and Entropy presented significant differences for ONwEN

. ONwoEN (both

=0.000)

ONwEN

. NON (both

=0.000) and NAON

. NON (both

0.05). ROC analysis demonstrated that the area under the curve (AUC) of histogram texture Energy were 0.758

0.795 and 0.701 for ONwEN

. ONwoEN

ONwEN

. NON and NAON

. NON

AUC of Entropy were 0.758

0.795 and 0.707 for ONwEN

. ONwoEN

ONwEN

. NON and NAON

. NON.

Conclusion

The altered MRI histogram texture Energy and Entropy could be considered as a surrogate for MRI enhancement to evaluate the involved optic nerve and normal-appearing optic nerve in optic neuritis.

关键词

Keywords

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