

FOLLOWUS
Department of Cardiology, the First Medical Center, Chinese PLA General Hospital, Beijing 100853, China
# These authors contributed equally to this work.
*, E-mail: cyundai@vip.163.com
Received:21 September 2018,
Accepted:2018-12-28,
Published Online:11 November 2019,
Published:11 November 2019
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Liu Chunwei, Li Zongbin, Guo Jun, et al. Physiological Variables Associated with the Development of Acute Mountain Sickness[J]. Chinese medical sciences journal, 2019, 34(4): 263-269.
Liu Chunwei, Li Zongbin, Guo Jun, et al. Physiological Variables Associated with the Development of Acute Mountain Sickness[J]. Chinese medical sciences journal, 2019, 34(4): 263-269. DOI: 10.24920/003518.
Bartsch P , Swenson ER . Clinical practice: acute high-altitude illnesses . N Engl J Med 2013 ; 368 ( 24 ): 2294 - 302 . doi: 10.1056/NEJMcp1214870 1001-9294-34-4-263/NEJMcp1214870 .
Roach RC , Hackett PH , Oelz O , et al . The 2018 Lake Louise Acute Mountain Sickness Score . High Alt Med Biol 2018 ; 19 ( 1 ): 4 - 6 . doi: 10.1089/ham.2017.0164 1001-9294-34-4-263/ham.2017.0164 .
Lu H , Wang R , Xiong J , et al . In search for better pharmacological prophylaxis for acute mountain sickness: looking in other directions . Acta Physiol (Oxf) 2015 ; 214 ( 1 ): 51 - 62 . doi: 10.1111/apha.12490 1001-9294-34-4-263/apha.12490 .
Kayser B , Verges S . Hypoxia, energy balance and obesity: from pathophysiological mechanisms to new treatment strategies . Obes Rev 2013 ; 14 ( 7 ): 579 - 92 . doi: 10.1111/obr.12034 1001-9294-34-4-263/obr.12034 .
Jin J . Acute mountain sickness . JAMA 2017 ; 318 ( 18 ): 1840 . doi: 10.1001/jama.2017.16077 1001-9294-34-4-263/jama.2017.16077 .
Luks AM , Swenson ER , Bartsch P . Acute high-altitude sickness . Eur Respir Rev 2017 ; 26 : 160096 . doi: 10.1183/16000617.0096-2016 1001-9294-34-4-263/16000617.0096-2016 .
Basnyat B , Murdoch DR . High-altitude illness . Lancet 2003 ; 361 ( 9373 ): 1967 - 74 . doi: 10.1016/S0140-6736(03)13591-X 1001-9294-34-4-263/S0140-6736(03)13591-X .
de Oliveira S , Rosowski EE , Huttenlocher A . Neutrophil migration in infection and wound repair: going forward in reverse . Nat Rev Immunol 2016 ; 16 ( 6 ): 378 - 91 . doi: 10.1038/nri.2016.49 1001-9294-34-4-263/nri.2016.49 .
Liu B , Chen J , Zhang L , et al . IL-10 dysregulation in acute mountain sickness revealed by transcriptome analysis . Front Immunol 2017 ; 8 : 628 . doi: 10.3389/fimmu.2017.00628 1001-9294-34-4-263/fimmu.2017.00628 .
Eltzschig HK , Carmeliet P . Hypoxia and inflammation . N Engl J Med 2011 ; 364 ( 7 ): 656 - 65 . doi: 10.1056/NEJMra0910283 1001-9294-34-4-263/NEJMra0910283 .
Hartmann G , Tschop M , Fischer R , et al . High altitude increases circulating interleukin-6, interleukin-1 receptor antagonist and C-reactive protein . Cytokine 2000 ; 12 ( 3 ): 246 - 52 . doi: 10.1006/cyto.1999.0533 1001-9294-34-4-263/cyto.1999.0533 .
Boos CJ , Woods DR , Varias A , et al . High altitude and acute mountain sickness and changes in circulating Endothelin-1, Interleukin-6, and Interleukin-17a . High Alt Med Biol 2016 ; 17 ( 1 ): 25 - 31 . doi: 10.1089/ham.2015.0098 1001-9294-34-4-263/ham.2015.0098 .
Hackett PH , Roach RC . High-altitude illness . N Engl J Med 2001 ; 345 ( 2 ): 107 - 14 . doi: 10.1056/NEJM200107123450206 1001-9294-34-4-263/NEJM200107123450206 .
Julian CG , Subudhi AW , Wilson MJ , et al . Acute mountain sickness, inflammation, and permeability: new insights from a blood biomarker study . J Appl Physiol 2011 ; 111 ( 2 ): 392 - 9 . doi: 10.1152/japplphysiol.00391.2011 1001-9294-34-4-263/japplphysiol.00391.2011 .
Bailey DM , Rimoldi SF , Rexhaj E , et al . Oxidative-nitrosative stress and systemic vascular function in highlanders with and without exaggerated hypoxemia . Chest 2013 ; 143 ( 2 ): 444 - 51 . doi: 10.1378/chest.12-0728 1001-9294-34-4-263/chest.12-0728 .
Irarrazaval S , Allard C , Campodonico J , et al . Oxidative stress in acute hypobaric hypoxia . High Alt Med Biol 2017 ; 18 ( 2 ): 128 - 34 . doi: 10.1089/ham.2016.0119 1001-9294-34-4-263/ham.2016.0119 .
Bailey DM , Taudorf S , Berg RM , et al . Increased cerebral output of free radicals during hypoxia: implications for acute mountain sickness? Am J Physiol Regul Integr Comp Physiol 2009 ; 297 ( 5 ): R1283 - 92 . doi: 10.1152/ajpregu.00366.2009 1001-9294-34-4-263/ajpregu.00366.2009 .
Diebel LN , Liberati DM , Taub JS , et al . Intestinal epithelial cells modulate PMN activation and apoptosis following bacterial and hypoxic challenges . J Trauma 2005 ; 58 ( 6 ): 1126 - 33 . doi: 10.1097/01.ta.0000169952.50045.f4 1001-9294-34-4-263/01.ta.0000169952.50045.f4 .
Kannan KB , Colorado I , Reino D , et al . Hypoxia-inducible factor plays a gut-injurious role in intestinal ischemia reperfusion injury . Am J Physiol Gastrointest Liver Physiol 2011 ; 300 ( 5 ): G853 - 61 . doi: 10.1152/ajpgi.00459.2010 1001-9294-34-4-263/ajpgi.00459.2010 .
Kleessen B , Schroedl W , Stueck M , et al . Microbial and immunological responses relative to high-altitude exposure in mountaineers . Med Sci Sports Exerc 2005 ; 37 ( 8 ): 1313 - 8 . doi: 10.1249/01.mss.0000174888.22930.e0 1001-9294-34-4-263/01.mss.0000174888.22930.e0 .
Karl JP , Hatch AM , Arcidiacono SM , et al . Effects of psychological, environmental and physical stressors on the gut microbiota . Front Microbiol 2018 ; 9 : 2013 . doi: 10.3389/fmicb.2018.02013 1001-9294-34-4-263/fmicb.2018.02013 .
Recavarren-Arce S , Ramirez-Ramos A , Gilman RH , et al . Severe gastritis in the Peruvian Andes . Histopathology 2005 ; 46 ( 4 ): 374 - 9 . doi: 10.1111/j.1365-2559.2005.02102.x 1001-9294-34-4-263/j.1365-2559.2005.02102.x .
Wu TY , Ding SQ , Liu JL , et al . Who should not go high: chronic disease and work at altitude during construction of the Qinghai-Tibet railroad . High Alt Med Biol 2007 ; 8 ( 2 ): 88 - 107 . doi: 10.1089/ham.2007.1015 1001-9294-34-4-263/ham.2007.1015 .
Zhang S , Wu T . Study on the relationship between systemic inflammatory response syndrome and acute mountain sickness syndrome . Med J NDFNC 2007 ; 28 ( 2 ): 81 - 3 . Chinese. doi: 10.16021/j.cnki.1007-8622.2007.02.001 1001-9294-34-4-263/j.cnki.1007-8622.2007.02.001 .
Roach RC , Greene ER , Schoene RB , et al . Arterial oxygen saturation for prediction of acute mountain sickness . Aviat Space Environ Med 1998 ; 69 ( 12 ): 1182 - 1185 .
Anholm JD . The VIIIth World Congress of high altitude medicine and physiology, Arequipa, Peru, August 8-12, 2010 . High Alt Med Biol 2010 ; 11 ( 4 ): 381 - 4 . doi: 10.1089/ham.2010.1061 1001-9294-34-4-263/ham.2010.1061 .
Lipman GS , Kanaan NC , Holck PS , et al . Ibuprofen prevents altitude illness: a randomized controlled trial for prevention of altitude illness with nonsteroidal anti-inflammatories . Ann Emerg Med 2012 ; 59 ( 6 ): 484 - 90 . doi: 10.1016/j.annemergmed.2012.01.019 1001-9294-34-4-263/j.annemergmed.2012.01.019 .
Gertsch JH , Corbett B , Holck PS , et al . Altitude sickness in climbers and efficacy of NSAIDs trial (ASCENT): randomized, controlled trial of ibuprofen versus placebo for prevention of altitude illness . Wilderness Environ Med 2012 ; 23 ( 4 ): 307 - 15 . doi: 10.1016/j.wem.2012.08.001 1001-9294-34-4-263/j.wem.2012.08.001 .
Basnyat B , Gertsch JH , Johnson EW , et al . Efficacy of low-dose acetazolamide (125 mg BID) for the prophylaxis of acute mountain sickness: a prospective, double-blind, randomized, placebo-controlled trial . High Alt Med Biol 2003 ; 4 ( 1 ): 45 - 52 . doi: 10.1089/152702903321488979 1001-9294-34-4-263/152702903321488979 .
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