Research Advances in the Role of Keratins in Gastrointestinal Cancer

Ouyang Siwen; Kang Weiming

doi:10.24920/003990

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Research Advances in the Role of Keratins in Gastrointestinal Cancer

Chinese Medical Sciences Journal Vol. 37, Issue 1, Pages: 73-78(2022)

Review | Updated：2024-04-10

- Research Advances in the Role of Keratins in Gastrointestinal Cancer
- Affiliations：
  
  1. 1Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China
  2. 2Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100010, China
- Author bio：
  
  *E-mail: pumchkangweiming@126.com.
- Funds：
- DOI：10.24920/003990
  CLC：
- Received：30 August 2021，
  
  Accepted：2021-12-23，
  
  Published Online：09 March 2022，
  
  Published：31 March 2022
- Accepted：
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Ouyang Siwen, Kang Weiming. Research Advances in the Role of Keratins in Gastrointestinal Cancer[J]. Chinese medical sciences journal, 2022, 37(1): 73-78.
DOI：

Ouyang Siwen, Kang Weiming. Research Advances in the Role of Keratins in Gastrointestinal Cancer[J]. Chinese medical sciences journal, 2022, 37(1): 73-78. DOI： 10.24920/003990.

摘要

胃肠道肿瘤的发病率和死亡率居高不下。尽管诊断和治疗技术在不断改进

胃肠道肿瘤的早期诊断、中期和晚期治疗、药物耐受性以及癌症复发和转移等问题仍构成巨大挑战。在本篇综述中

我们总结了角蛋白在胃肠道肿瘤中的作用和研究进展

希望它们能成为预测、诊断或治疗胃肠道肿瘤的有效生物标志物。

Abstract

The incidence and mortality rates of gastrointestinal (GI) cancer remain high. Despite constant improvements in diagnostic and therapeutic techniques

the early diagnosis

mid- and late-stage treatment

drug tolerance

and cancer recurrence and metastasis in GI cancer remain challenging. In this review article we summarize the recent research advance in the roles of keratins in GI cancer

with the hope that they will become efficient biomarkers for the prediction

diagnosis

or treatment of these malignancies.

关键词

Keywords

references

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