FOLLOWUS
1. 1Department of Anesthesiology, Beijing 100730, China
2. 2Medical Research Center;Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China
* 86-10-69152026, E-mail: pumchshenle@163.com
Received:23 June 2022,
Accepted:2022-9-30,
Published Online:10 October 2022,
Published:31 December 2022
Scan QR Code
Xue Zhang, Lingeer Wu, Huizhen Huang, et al. Risk Factors for Anesthesia-Related Airway Patient Safety Incidents: A Single-Center Retrospective Case-Control Analysis from 2009 to 2022[J]. Chinese medical sciences journal, 2022, 37(4): 287-292.
Xue Zhang, Lingeer Wu, Huizhen Huang, et al. Risk Factors for Anesthesia-Related Airway Patient Safety Incidents: A Single-Center Retrospective Case-Control Analysis from 2009 to 2022[J]. Chinese medical sciences journal, 2022, 37(4): 287-292. DOI: 10.24920/004130.
目的
麻醉相关气道不良事件是麻醉医师最关注的不良事件类型,此类不良事件若处理不及时或不恰当,可能严重威胁患者生命安全。本研究旨在分析麻醉医师上报气道不良事件的组成及患者预后,并寻找可能的相关危险因素。
方法
我们采集了所有北京协和医院2009年9月至2022年5月由麻醉医师在系统中上报的气道相关不良事件数据。发生气道不良事件的病例按照相同性别及相同手术类型与未发生不良事件病例进行1:1匹配。我们通过单因素及多因素分析方法,寻找与气道不良事件发生相关的危险因素,并分析气道不良事件对患者预后的影响。
结果
在研究期间,麻醉医师共在系统中上报不良事件1
038例,其中281例(27.1%)为气道相关不良事件,整体上报率为4.74/10
000。仅ASA分级是发生此类不良事件的独立相关因素(
P
= 0.002)。发生气道相关不良事件的患者拔管时间(0.72 ± 1.56 d比0.16 ± 0.77 d,95%
CI
:0.29~0.82,
P
<
0.001)、ICU住院日(1.63 ± 5.71 d比0.19 ± 0.84 d,95%
CI
:0.57~2.32,
P
= 0.001)及总住院日(14.99 ± 15.18 d比11.62 ± 11.88 d,95%
CI
:0.46~6.27,
P
= 0.024)均显著延长。
结论
本单中心回顾性病例对照研究描述了13年间麻醉医师上报气道相关不良事件的组成。气道不良事件可能通过延长拔管时间及住院日影响患者预后。气道相关不良事件值得更多关注,以保障患者安全。
Objective
Airway-related patient safety incident (PSI) has always been the top concern of anesthesiologists because this type of incidents could severely threaten patient safety if not treated immediately and properly. This study intends to reveal the composition
prognosis
and to identify risk factors for airway related incidents reported by anesthesiologists.
Methods
All airway related PSIs reported by anesthesiologists in a Chinese academic hospital between September 2009 and May 2022 were collected from the PSI reporting system. Patients with airway incidents reported were matched 1:1 with controls based on sex and type of surgery. Univariable and multivariable analysis were performed to find risk factors associated with airway incident occurrence
and to evaluate influence of airway PSIs on patient prognosis.
Results
Among 1
038 PSIs voluntarily reported by anesthesiologists during the study period
281 cases (27.1%) were airway-related incidents
with an overall reporting incidence of 4.74 per 10
000 among 592
884 anesthesia care episodes. Only ASA physical status was found to be significant independent predictor of these airway PSIs (
P
= 0.020). Patients with airway PSIs reported had longer extubation time (0.72 ± 1.56 d
vs
. 0.16 ± 0.77 d
95%
CI
: 0.29 to 0.82
P
<
0.001)
longer ICU length of stay (LOS) (1.63 ± 5.71 d
vs
. 0.19 ± 0.84 d
95%
CI
: 0.57 to 2.32
P
= 0.001)
longer post operative LOS (10.56 ± 13.09 d
vs
. 7.59 ± 10.76 d
95%
CI
: 0.41 to 5.53
P
= 0.023)
and longer total in-hospital LOS (14.99 ± 15.18 d
vs
. 11.62 ± 11.88 d
95%
CI
: 0.46 to 6.27
P
= 0.024).
Conclusions
This single-center retrospective case-control study describes the composition of airway-related PSIs reported by anesthesiologists within thirteen years. Airway incidents might influence patient prognosis by elongating extubation time and LOS. Airway PSI data were worth analyzing to improve patient safety.
World Health Organization . ‘More than words’—conceptual framework for the international classification for patient safety . Geneva : World Health Organization; 2009 .
Zhang X , Ma S , Sun X , et al . Composition and risk assessment of perioperative patient safety incidents reported by anesthesiologists from 2009 to 2019: a single-center retrospective cohort study . BMC Anesth 2021 ; 21 ( 1 ): 8 . doi: 10.1186/s12871-020-01226-0 https://dx.doi.org/10.1186/s12871-020-01226-0 . DOI: 10.1186/s12871-020-01226-0 http://doi.org/10.1186/s12871-020-01226-0
Saito T , Wong ZW , Thinn KK , et al . Review of critical incidents in a university department of anaesthesia . Anesth Intensive Care 2015 ; 43 ( 2 ): 238 - 43 . doi: 10.1177/0310057X1504300215 https://dx.doi.org/10.1177/0310057X1504300215 . DOI: 10.1177/0310057X1504300215 http://doi.org/10.1177/0310057X1504300215
Thomas AN , Taylor RJ . Review of patient safety incidents reported from 541 critical care units in North-West England in 2009 and 2010 . Anaesthesia 2012 ; 67 ( 7 ): 706 - 13 . doi: 10.1111/j.1365-2044.2012.07141.x https://dx.doi.org/10.1111/j.1365-2044.2012.07141.x . DOI: 10.1111/j.1365-2044.2012.07141.x http://doi.org/10.1111/j.1365-2044.2012.07141.x
Thomas AN , McGrath BA . Patient safety incidents associated with airway devices in critical care: a review of reports to the UK National Patient Safety Agency . Anesthesia 2009 ; 64 ( 4 ): 358 - 65 . doi: 10.1111/j.1365-2044.2008.05784.x https://dx.doi.org/10.1111/j.1365-2044.2008.05784.x . DOI: 10.1111/j.1365-2044.2008.05784.x http://doi.org/10.1111/j.1365-2044.2008.05784.x http://blackwell-synergy.com/doi/abs/10.1111/ana.2009.64.issue-4 http://blackwell-synergy.com/doi/abs/10.1111/ana.2009.64.issue-4
Cook TM , Woodall N , Harper J , et al . Fourth National Audit Project. Major complications of airway management in the UK: results of the Fourth National Audit Project of the Royal College of Anaesthetists and the Difficult Airway Society. Part 2: intensive care and emergency departments . Br J Anesth 2011 ; 106 ( 5 ): 632 - 42 . doi: 10.1093/bja/aer059 https://dx.doi.org/10.1093/bja/aer059 . DOI: 10.1093/bja/aer059 http://doi.org/10.1093/bja/aer059 https://linkinghub.elsevier.com/retrieve/pii/S0007091217332105 https://linkinghub.elsevier.com/retrieve/pii/S0007091217332105
Alonso-Ovies Á , Nin N , Martín MC , et al . Safety incidents in airway and mechanical ventilation in Spanish ICUs: the IVeMVA study . J Crit Care 2018 ; 47 : 238 - 44 . doi: 10.1016/j.jcrc.2018.07.012 https://dx.doi.org/10.1016/j.jcrc.2018.07.012 . DOI: S0883-9441(18)30321-6 http://doi.org/S0883-9441(18)30321-6
Mitchell I , Schuster A , Smith K , et al . Patient safety incident reporting: a qualitative study of thoughts and perceptions of experts 15 years after ‘To Err is Human’ . BMJ Qual Saf 2016 ; 25 ( 2 ): 92 - 9 . doi: 10.1136/bmjqs-2015-004405 https://dx.doi.org/10.1136/bmjqs-2015-004405 . DOI: 10.1136/bmjqs-2015-004405 http://doi.org/10.1136/bmjqs-2015-004405
Mahajan RP . Critical incident reporting and learning . Br J Anesth 2010 ; 105 ( 1 ): 69 - 75 . doi: 10.1093/bja/aeq133 https://dx.doi.org/10.1093/bja/aeq133 . DOI: 10.1093/bja/aeq133 http://doi.org/10.1093/bja/aeq133 https://linkinghub.elsevier.com/retrieve/pii/S0007091217335687 https://linkinghub.elsevier.com/retrieve/pii/S0007091217335687
Wallace LM , Spurgeon P , Benn J , et al . Improving patient safety incident reporting systems by focusing upon feedback-lessons from English and Welsh trusts . Health Serv Manage Res 2009 ; 22 ( 3 ): 129 - 35 . doi: 10.1258/hsmr.2008.008019 https://dx.doi.org/10.1258/hsmr.2008.008019 . DOI: 10.1258/hsmr.2008.008019 http://doi.org/10.1258/hsmr.2008.008019 http://journals.sagepub.com/doi/10.1258/hsmr.2008.008019 http://journals.sagepub.com/doi/10.1258/hsmr.2008.008019
Frerk C , Mitchell VS , McNarry AF , et al . Difficult Airway Society 2015 guidelines for management of unanticipated difficult intubation in adults . Br J Anesth 2015 ; 115 ( 6 ): 827 - 48 . doi: 10.1093/bja/aev371 https://dx.doi.org/10.1093/bja/aev371 . DOI: 10.1093/bja/aev371 http://doi.org/10.1093/bja/aev371 https://linkinghub.elsevier.com/retrieve/pii/S0007091217314319 https://linkinghub.elsevier.com/retrieve/pii/S0007091217314319
Kornas RL , Owyang CG , Sakles JC , et al . Evaluation and management of the physiologically difficult airway: consensus recommendations from Society for Airway Management . Anesth Analg 2021 ; 132 ( 2 ): 395 - 405 . doi: 10.1213/ANE.0000000000005233 https://dx.doi.org/10.1213/ANE.0000000000005233 . DOI: 10.1213/ANE.0000000000005233 http://doi.org/10.1213/ANE.0000000000005233
Apfelbaum JL , Hagberg CA , Connis RT , et al . 2022 American Society of Anesthesiologists Practice Guidelines for Management of the Difficult Airway . Anesthesiology 2022 ; 136 ( 1 ): 31 - 81 . doi: 10.1097/ALN.0000000000004002 https://dx.doi.org/10.1097/ALN.0000000000004002 . DOI: 10.1097/ALN.0000000000004002 http://doi.org/10.1097/ALN.0000000000004002
Kaiser HA , Saied NN , Kokoefer AS , et al . Incidence and prediction of intraoperative and postoperative cardiac arrest requiring cardiopulmonary resuscitation and 30-day mortality in non-cardiac surgical patients . PLoS One 2020 ; 15 ( 1 ): e0225939 . doi: 10.1371/journal.pone.0225939 https://dx.doi.org/10.1371/journal.pone.0225939 . DOI: 10.1371/journal.pone.0225939 http://doi.org/10.1371/journal.pone.0225939
Sobreira-Fernandes D , Teixeira L , Lemos TS , et al . Perioperative cardiac arrests—a subanalysis of the anesthesia-related cardiac arrests and associated mortality . J Clin Anesth 2018 ; 50 : 78 - 90 . doi: 10.1016/j.jclinane.2018.06.005 https://dx.doi.org/10.1016/j.jclinane.2018.06.005 . DOI: S0952-8180(18)30260-5 http://doi.org/S0952-8180(18)30260-5
Banik RK , Honeyfield K , Qureshi S , et al . Incidence and mortality rate of perioperative reintubation: case series of 196 patients . AANA J 2021 ; 89 ( 6 ): 476 - 9 .
Endlich Y , Beckmann LA , Choi SW , et al . A prospective six-month audit of airway incidents during anesthesia in twelve tertiary level hospitals across Australia and New Zealand . Anesth Intensive Care 2020 ; 48 ( 5 ): 389 - 98 . doi: 10.1177/0310057X20945325 https://dx.doi.org/10.1177/0310057X20945325 . DOI: 10.1177/0310057X20945325 http://doi.org/10.1177/0310057X20945325
Publicity Resources
Related Articles
Related Author
Related Institution