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Causal Relationships Between Mineralocorticoid Receptor Activation and Tubulointerstitial Nephritis and Lipid Metabolism Dysregulation: A Mendelian Randomization Study
Chinese Medical Sciences Journal   Vol. 40, Issue 2, Pages: 132-143(2025)
Research Article | Updated：2025-07-21

    • Causal Relationships Between Mineralocorticoid Receptor Activation and Tubulointerstitial Nephritis and Lipid Metabolism Dysregulation: A Mendelian Randomization Study

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    • “In a groundbreaking study, researchers have uncovered the causal link between cytoplasmic unactivated mineralocorticoid receptor levels and the risk of tubulointerstitial nephritis, as well as its impact on lipid metabolism in diabetic kidney disease patients. This discovery could pave the way for the development of MR-antagonists to mitigate renal damage and lipid metabolism-related complications.”

    • DOI：10.24920/004447    

      CLC：

    • Received：11 November 2024，

      Accepted：09 April 2025，

      Published Online：24 June 2025，

      Published：30 June 2025

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  • He Min,Yang Xiao-Ping.Causal Relationships Between Mineralocorticoid Receptor Activation and Tubulointerstitial Nephritis and Lipid Metabolism Dysregulation: A Mendelian Randomization Study[J].Chinese Medical Sciences Journal,2025,40(02):132-143.doi: 10.24920/004447 DOI：

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