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Causal Relationships Between Mineralocorticoid Receptor Activation and Tubulointerstitial Nephritis and Lipid Metabolism Dysregulation: A Mendelian Randomization Study
Chinese Medical Sciences Journal   Pages: 1-13(2025)
Updated：2025-06-24

    • Causal Relationships Between Mineralocorticoid Receptor Activation and Tubulointerstitial Nephritis and Lipid Metabolism Dysregulation: A Mendelian Randomization Study

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    • “In a groundbreaking study, researchers have uncovered the causal link between cytoplasmic unactivated mineralocorticoid receptor levels and the risk of tubulointerstitial nephritis, as well as its impact on lipid metabolism in diabetic kidney disease patients. This discovery could pave the way for the use of MR-antagonists like finerenone in mitigating renal damage and lipid-related complications.”

    • DOI：10.24920/004447    

      CLC：

    • Received：11 November 2024，

      Accepted：09 April 2025，

      Published Online：24 June 2025，

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  • He Min,Yang Xiao-Ping.Causal Relationships Between Mineralocorticoid Receptor Activation and Tubulointerstitial Nephritis and Lipid Metabolism Dysregulation: A Mendelian Randomization Study[J].Chinese Medical Sciences Journal, DOI：.org/10.24920/004447.

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