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Volume ， Issue 4 ， 1995
- Abstract：Cardiomyocytes isolated from neonatal rats were treated with phorboll 2-myristatel 3-acetate （PMA ） ranging from 10（-11）to 10-7 mol/L for 20 min, causing cytosol protein kinase A （PKA） activity to decrease while particulate PKA activity increase in a concentration-dependent manner. The change of PKA activity induced by PMA was abolished completely by pretreatment of polymyxin B or depletion of protein kinase C （PKC）. Type II PKA activity in particulate fraction was enhanced remarkably, while that of type I PKA was not altered when the cells were treated with 100 nmol/L PMA. The results suggested that subcellular distribution and activity of PKA in cardiomyocytes may be regulated by PKC.4|17|0Updated：2024-04-10
- Abstract：ＯｖｅｒｅｘｐｒｅｓｓｉｏｎｏｆＧＳＴ－πｉｎｔｈｅＡｄｒｉａｍｙｃｉｎｅ－ｒｅｓｉｓｔａｎｔＨｕｍａｎＬｕｎｇＣａｎｃｅｒＣｅｌｌＬｉｎｅＺｈｏｕＺｈｏｎｇｊｕｎ（周中军），ＬｕｏＸｉａｎｍａｏ（罗贤懋），ＬｉｎＣｈｅｎ（林晨），ＣｈｅｎＦｅｎｇ(...4|8|1Updated：2024-04-10
- Abstract：In an attempt to identify the taxonomic relationship between CAR bacillus and other bacteria, the SSU rRNA gene sequences of two CAR bacillus strains, CBM and CBR isolated from mice and rats respectively were used in the present studies. The SSU rRNA gene sequences, approximately 1. 5 kb in size amplified from genomic DNAs from both strains, were determined and 96. 8% homologies were found to exist between them. Those sequences were aligned to most eubacteria with a computer search showing high homology with those of Flavobacter/Flexibacter species especially closed to Fx. sancti and Fv. ferrugineum.Phylogenetic analysis indicated that CAR bacillus belongs to a species close to Fx. sancti and Fv. ferrugineum subdivision.4|38|0Updated：2024-04-10
- Abstract：ＥｖａｌｕａｔｉｏｎｏｆＰｒｅ－ａｎｄＰｏｓｔ－ＤｅｌｉｖｅｒｙＣｈａｎｇｅｓｏｆＣａｒｄｉａｃＦｕｎｃｔｉｏｎａｎｄＨｅｍｏｄｙｎａｍｉｃｓｂｙＤｏｐｐｌｅｒＥｃｈｏｃａｒｄｉｏｇｒａｐｈｙｉｎＰｒｅｇｎａｎｔＷｏｍｅｎＬｉＣｈｕｎｓｈｅｎｇ(李春...4|9|0Updated：2024-04-10
- Abstract：One hundred and eleven cases of oral squamous cell carcinoma （OSCC） were examined for overexpression of p53 protein by using immunohistochemical technique. Association between p53 protein overexpression and clinical and pathological parameters as well as prognosis of patients were also analyzed. p53 protein overexpression was commonly observed （69. 4%） in OSCC and may be used as a marker of carcinogenesis of OSCC. The level of p53 protein overexpression is correlated with the lower three and five-year survival rate of OSCC. The presence or absence of p53 overexpression was not correlated with sex, age, site of tumor, size of tumor, degree of differentiation,node status,and clinical stage in OSCC. Single factor COX proportional hazards regression model analysis indicated that there was no significant association between p53 overexpression and prognosis of OSCC. Multivariable COX model analysis failed to establish effective life function or risk rate function. These showed that all the parameters analyzed in this study as well as p53 overexpression were not significant and effective risk factors of prognosis for patients with OSCC.4|9|1Updated：2024-04-10
- Abstract：We attempted to classify, according to the International Classification of Epilepsies and Epileptic Syndromes （1989）, 302 patients at a tertiary epilepsy referral center. Proportion in categories as defined by the international League Against Epilepsy （ILAE） were as follows: localization-related epilepsies: 62. 9 %,generalized epilepsies: 22. 2%,epilepsies undetermined whether focal or generalized: 14. 2%, special syndromes: 0. 7%. Only 26. 8 % cases were definitely classified in single diagnostic ILAE categories based on ictal CCTV/EEG recordings. The distribution of epileptic syndromes was different from the previous reports due to various methods of case ascertainment and inclusion criteria. Use of specific criteria for the reliability study of international classification has been proposed.4|8|0Updated：2024-04-10
- Abstract：The effects of CH925, a novel immune modulator, on hepadna virus infection was evaluated. Day-old ducklings were inoculated intravenously with LJ-76 DHBV containing serum. Infected ducklings were then treated with the CH925 and the mixture of IL-2 and IL-6 intravenously and the control ducklings received equivalent normal saline （NS）. Blood and liver samples were taken and assayed for DHBV DNA and /or DHBsAg. At the completion of the experiment there was a inhibition of viremia with the CH925 and IL-2 + IL-6. Serum DHBV DNA was detected in 6 of 10 ducks in 100 000 unit/kg dosage group, 7 of 10 ducks in 50 000 unit/kg dosage group and 6 of 10 ducks in IL-2 + IL-6 dosage group, compared with 9 of 10 NS control, and it showed a similar result in circulating DHBsAg. When samples of liver DNA were processed for hybridization, a little difference in the DHBV DNA replication was noted between ducks receiving CH925, IL-2 + IL-6 or NS placebo. It is suggested that CH925 might be a potential remedy in HBV infection treatment.4|14|0Updated：2024-04-10
- Abstract：Plasma dynorphin A1-13 levels were measured in 33 patients with mitral stenosis before and after percutaneous balloon mitral commissurotomy （PBMC）. The results show that the basal levels of plasma dynorphin in blood from the antecubital vein in the patients were significantly higher than those in 31 healthy control subjects. The increase in circulating dynorphin closely correlated with the functional cardiac status and the presence of atrial fibrillation. Ten to fifteen minutes after PBMC, plasma dynorphin levels in blood from the femoral vein increased significantly. Seventy-two hours after the procedure, the levels of plasma dynorphin in blood from the antecubital vein had decreased significantly , but they did not decrease to the normal range. Plasma dynorphin levels in blood from the femoral vein were positively correlated with the mean left atrial pressure and the mean right atrial pressure before the first balloon inflation. Plasma dynorphin levels in blood from the antecubital vein were positively correlated with the heart rate and the mean transmitral pressure gradient, and negatively with the mitral valve area before and 72 hours after PBMC.4|7|0Updated：2024-04-10
- Abstract：An immunocytochemical study was performed in 6 peripheral nerve specimens from 6 cases of polymyositis. The results revealed that depositions of IgG, IgM, IgA and C3 were found in the epineurium, perineurium and the walls of capillaries. These findings demonstrated that depositions of immunoglobulins and the complement-mediated immunoreaction may play an important role in pathogenesis of polymyositis with peripheral nerve involvements.4|9|0Updated：2024-04-10
- Abstract：In this study, we characterized specifically-stained sera from patients with systemic lupus erythematosus （SLE） which had been shown to display the homogeneous or peripheral region of nuclei by indirect immunofluorescence （IIF）. By western blotting, we demonstrated that in some cases there was a correlation between the peripheral or homogenous. IIF staining of nuclei by sera from patients with SLE and the presence of autoantibodies to lamins. Here we first report the presence of 2. 2% anti-lamin autoantibodies in the sera among the 174 patients with SLE in China.4|7|0Updated：2024-04-10
- Abstract：Six tibias removed from 30-40 years old males, who died in an accident for in less than 12 hours, were osteotomized at one-third supra-medium segment. They were fixed by an unilateral adjustable external fixer （UAEF）, to be used as a model of external fixation of tibial fracture （MEFTF）. The compression. tension, torsion, antero-posterior and lateral bending strength, and the strength for vertically extracting the pins from the tibia were determined in the MEFTF. Within a certain range of load, the correlation of strain to stress was basically a linear relationship. These data provide a theoretical basis of biomechanics for the improvement of UAEF and for early exercises of fracture patients, such as extend-bending of the joint.raising the limb and walking with a walking stick.4|5|2Updated：2024-04-10
- Abstract：One hundred and ten cases of thymic tumors were intervened surgically, including 92 thymoma, 8 thymic carcinoid, and 10 thymic carcinoma. In this series, 50. 9% of the cases were complieated with various syndromes, 44. 5 % with myasthenia gravis （MG）. Resection rate was correlated with the size and invasion of the tumor. There was significant difference in resection rate among thymoma, thymic carcinoid and thymic carcinoma. The degree of invasion undoubtely influenced on resection. The 3 -,5- and 10- year suvival rate of the thymoma were 82. 7 %, 68. 1% and 40. 0 %, respectively. The prognosis depended on the pathological classification and the severity of the neighbouring invasion, but MG had no significant effect on prognosis. Recurrence and metastasis of the tumor were the main cause of late death.4|7|0Updated：2024-04-10
- Abstract：ＰｈｏｓｐｈｏｒｙｌａｔｉｏｎｂｙＰｒｏｔｅｉｎＫｉｎａｓｅＣＭｏｄｕｌａｔｅｓＤＮＡＢｉｎｄｉｎｇＡｃｔｉｖｉｔｙｏｆＮｏｎｈｉｓｔｏｎｅＨｉｇｈＭｏｂｉｌｉｔｙＧｒｏｕｐＩＰｒｏｔｅｉｎＸｉａｏＤｉａｎｍｏ（肖殿模）(ＩｎｓｔｉｔｕｔｅｏｆＢａｓ...4|4|0Updated：2024-04-10
- Abstract：In 19 patients with idiopathic dilated cardiomyopathy and symptoms of congetive heart failure, left ventricular （LV） systolic performance and diastolic velocity profiles were assessed by two- dimensional echocardiography and pulsed wave Doppler at rest and during handgrip exercise before and ninety minutes after administration of captopril （mean dose 25 +12mg; range 12. 5─50mg）. Although heart rate and blood pressure increased similarly during handgrip exercise before and after captopril treatment, both were lower with handgrip exercise during captopril treatment. The results from this study indicated that acute angiotensin converting enzyme inhibition with captopril reduces preload and afterload and ameliorates handgrip exercise-induced LV systolic and diastolic filling dysfunction in patients with congestive heart failure secondary to idiopathic dilated cardiomyopathy.4|7|0Updated：2024-04-10
- Abstract：In order to investigate the mechanisms of acute cerebral ischemia, and to look for effective drugs on cerebral resuscitation, we made a model of acute complete global brain ischemia, reperfusion and resuscitation on rats according to Garavilla’s method.Our results showed that the event of cerebral ischemia and reperfusion injury could resuh in the increase of total brain calcium content, and anisodamine has the same reducing brain calcium contents as diltiazem’s, while improving neurological outcome and alleviating injury to neurons.4|16|1Updated：2024-04-10
- Abstract：Ｂａｎｄ－ＳｔａｂｄｓＤＮＡＣｙｃｌｅＳｅｑｕｅｎｃｉｎｇＭｉａｏＳｈｉｒｏｎｇ；（苗世荣），ＸｕＳｈｕｎｂｉｎ；（许顺滨），ＬｉｕＧｕｏｙａｎｇ；（刘国仰），ＨｕａｎｇＳｈａｎｇｚｈｉ（黄尚志）ａｎｄＷｉｌｓｏｎＨ．Ｙ．Ｌｏ（罗会元）(Ｄｅｐａｒｔ...4|3|0Updated：2024-04-10
- Abstract：ＳｔｕｄｙｏｎＣｅｌｌｕｌａｒＲｅｓｐｏｎｓｅｔｏＩｎｊｅｃｔｉｏｎｏｆＳｃｈｉｓｔｏｓｏｍａｊａｐｏｎｉｃｕｍＥｇｇｓｉｎｔｏｔｈｅＬｉｖｅｒｓａｎｄＳｐｌｅｅｎｓｏｆＣ５７ＢＬ／６ＭｉｃｅＸｕＨｕ（许浒），ＸｕｅＷａｎｆｅｎ（薛婉芬）ａｎｄＸｕＢ...6|4|0Updated：2024-04-10
- Abstract：ＮｉｔｒｉｃＯｘｉｄｅＳｙｎｔｈａｓｅＥｘｐｒｅｓｓｉｏｎａｎｄＤｙｎｏｒｐｈｉｎ－ｉｎｄｕｃｅｄＳｐｉｎａｌＣｏｒｄＩｎｊｕｒｙｉｎＲａｔｓＨｕＷｅｎｈｕｉ（胡文辉），ＷａｎＸｕａｎｃａｉＳ．Ｔ．（万选才），ＬｉＦｕｃｈｕｎ（李富春）ａｎｄＲｅｎＭ...4|5|0Updated：2024-04-10
- Abstract：ＵｌｔｒａｓｏｕｎｄＤｏｐｐｌｅｒＳｐｅｃｔｒａｌＡｎａｌｙｓｉｓｉｎＤｉａｇｎｏｓｉｓｏｆＴａｋａｙａｓｕＡｒｔｅｒｉｔｉｓＷａｎｇＪｉｎｇｙｉ（王静毅），ＬｉｕＭｅｉｚｈｅｎ（刘美贞），ＰａｎＹｏｎｇｍｅｉ（潘永梅）ａｎｄＺｈｏｕＨｕｉｑｉｎｇ(...4|6|0Updated：2024-04-10
- Abstract：ＳｃｌｅｒｏｓｉｎｇＨｅｍａｎｇｉｏｍａｓｏｆｔｈｅＬｕｎｇＧｅＦｅｎｇ（戈烽），Ｇａｏｊｉｅ（高洁），ＬｉａｏＱｕａｎ（廖泉）ＸｉａｏＳｈｕｍｅｉ（尚蜀梅）ａｎｄＺｈａｎｇＺｈｉｙｏｎｇ（张志庸）(Ｄｅｐｔ．ｏｆＴｈｏｒａｃｉｃＳｕｒｇｅｒｙ，ＰＵ...4|8|0Updated：2024-04-10
- Abstract：ＣｌｉｎｉｃａｌＵｓｅｏｆＰｒｏｐｏｆｏｌ（Ｄｉｐｒｉｖａｎ）ｉｎＡｒｔｉｆｉｃｉａｌＡｂｏｒｔｉｏｎＹｅＴｉｅｈｕ；（叶铁虎），ＷａｎｇＬｉｎｇ；（王玲），ＦａｎＧｕａｎｇｓｈｅｎｇ；（范光升），ＲｅｎＨｏｎｇｚｈｉ（任洪智）ａｎｄＬｕｏＡｉｌｕｎ...4|7|1Updated：2024-04-10
- Abstract：ＳｃａｎｎｉｎｇＥｌｅｃｔｒｏｎＭｉｃｒｏｓｃｏｐｙＡｐｐｌｉｃａｔｉｏｎｓｉｎＦｏｒｅｎｓｉｃＭｅｄｉｃｉｎｅＬｉａｏＺｈｉｇａｎｇ（廖志钢），ＬｉｕＭｉｎ（刘敏），ＨｕａｎｇＦｅｉｊｕｎ（黄飞骏）ａｎｄＷｕＪｉａｗｅｎ（吴家文）(Ｆａｃｕｌｔｙｏ...4|14|0Updated：2024-04-10
- Abstract：ＥｆｆｅｃｔｓｏｆＤｏｐａｍｉｎｅｏｎｔｈｅＭａｘｉｍａｌＭｏｕｔｈＲｅｓｐｉｒａｔｏｒｙＰｒｅｓｓｕｒｅ─ＡＲａｎｄｏｍ，Ｄｏｕｂｌｅ－ｂｌｉｎｄ，Ｐｌａｃｅｂｏ－ｃｏｎｔｒｏｌｌｅｄ，ＣｒｏｓｓｏｖｅｒＳｔｕｄｙＺｈａｏＹｉｊｕ（赵一举），Ｃａｉ...4|8|0Updated：2024-04-10
- Abstract：ＳＵＢＪＥＣＴＩＮＤＥＸＣＨＩＮＥＳＥＭＥＤＩＣＡＬＳＣＩＥＮＣＥＳＪＯＵＲＮＡＬＶｏｌｕｍｅ１０，１９９５SUBJECT INDEX CHINESE MEDICAL SCIENCES JOURNAL...4|6|0Updated：2024-04-10
- Abstract：ＴｈｅＥｓｔａｂｌｉｓｈｍｅｎｔａｎｄＣｈａｒａｃｔｅｒｉｚａｔｉｏｎｏｆＴｗｏＣｅｌｌＳｔｒａｉｎｓＳｅｃｒｅｔｉｎｇＡｎｔｉｅａｒｌｙＰｒｅｇｎａｎｃｙＦａｃｔｏｒＭｏｎｏｃｌｏｎａｌＡｎｔｉｂｏｄｙＳｕＢａｏｔｉａｎ；（苏宝田），ＣｈｅｎＦｅｉ...4|6|0Updated：2024-04-10
- Abstract：ＭａｌｉｇｎａｎｔＰｅｒｉｔｏｎｅａｌＭｅｓｏｔｈｅｌｉｏｍａ──Ｒｅｐｏｒｔｏｆ４ＣａｓｅｓＺｈｏｕＺｅｎｇｆｅｎ（周曾芬）ａｎｄＺｈｏｕＣｈｏｎｇｂｉｎ（周崇斌）(ＤｉｇｅｓｔｉｖｅＭｅｄｉｃｉｎｅＤｅｐａｒｔｍｅｎｔｏｆｔｈｅＦｉｒｓｔＡｆｆｉ...4|5|0Updated：2024-04-10
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